1)hTNFα人肿瘤坏死因子
1.Human tumor necrosis factor alpha(hTNFα),as a pleiotropic cytokine capable of killing tumor cell in vitro and in vivo, has been thought a potential anti-tumor agent, but its side effects limiting its using in clinic.人肿瘤坏死因子(hTNFα)因其能在体内、外能特异杀伤肿瘤组织细胞而被认为是一种很有潜力的抗癌药物，然而它的毒副作用大大地限制了它在临床中的应用。
英文短句/例句
1.Studies on Tumor Targeting of Stealth Nanoparticles Loading Recombinant Human Tumor Necrosis Factor-alpha;重组人肿瘤坏死因子隐形纳米粒肿瘤靶向研究
2.Construction of a Novel Human TNF α Mutant基因重组人肿瘤坏死因子-α突变体的构建
3.Genetic Polymorphism of TNFα-238G/A in the Han of Guangdong广东汉族人肿瘤坏死因子α-238G/A基因多态性
4.Cloning, Expression, and Characterization of Human Tumor Necrosis Factor-like Weak Inducer of Apoptosis;人肿瘤坏死因子样弱凋亡因子的克隆、表达及功能研究
5.Effect of ~(131)I-labeled Recombinant Human Tumor Necrosis Factor-α on the Nude Mice Bearing Human Hepatoma碘-131标记重组人肿瘤坏死因子-α治疗荷人肝癌裸鼠的实验研究
6.Expression of Human Tumor Necrosis Factor Alpha in Anabaena sp. PCC7120 and Its Preliminary Purificationα型人肿瘤坏死因子在鱼腥藻7120中的表达及其初步纯化
7.Structure and Bioactivities Analysis of Human Tumor Necrosis Factor Alpha Mutated in Position 30 and 42 Amino Acid人肿瘤坏死因子α30和42位氨基酸突变体结构与生物活性分析
8.The Development of Neovasculature Endothelial Cells Targeted Recombinant Mutant Human Tumor Necrosis Factor Alpha;新生血管内皮细胞靶向性重组改构人肿瘤坏死因子的研制
9.Characterization, Expression and Extraction of Recombinant Humor Tumor Necrosis Factor α(rhTNFα) on Large Scale;重组人肿瘤坏死因子α（rhTNFα）的鉴定、表达及大规模提取的研究
10.Research Progress of Tumor Necrosis Factor and Its Genetic Engineering;肿瘤坏死因子及其基因工程研究进展
11.Correlation Study of the TNF-α and Psoriasis;肿瘤坏死因子—α与银屑病相关性研究
12.Function of Tumor Related Apoptosis Inducing-ligand to Human Osteosarcoma Cells肿瘤坏死因子相关凋亡诱导配体对人骨肉瘤的作用
13.The Antitumor Activity of Human Glioma Infiltrating Lymphocytes Transduced by TNF α Gene肿瘤坏死因子α基因转导人脑胶质瘤浸润淋巴细胞的抗肿瘤活性研究
14.The Mechanism of Brain Edema Induced by Tumor Necrosis Factor-Alpha;肿瘤坏死因子-α诱发脑水肿机制的实验研究
15.Research progress of tumor necrosis factor-α and its receptor in bone resorption of inflammatory diseases肿瘤坏死因子-α及其受体与炎症性骨破坏
16.TNF-a Gene Polymorphisms in Myasthenia Gravis;肿瘤坏死因子-a-308基因多态性在重症肌无力病人中的表达
17.The Experiment of Metal Ion Stimulate Human Mononuclear Cell Apoptosis and Produce TNF-α;金属离子诱导人单核细胞凋亡并释放肿瘤坏死因子的实验研究
18.The Study of Expression of TNF-α mRNA and TNF-R_2 in Human Spermatozoa;肿瘤坏死因子-αmRNA及其受体Ⅱ在人精子表达的研究
相关短句/例句
hTNF-α gene人肿瘤坏死因子α基因
3)rhTNF-α重组人肿瘤坏死因子
1.To study the effects of recombinant human tumor necrosis factor-alpha ( rhTNF-α) on HL-60 cells in vitro and in vivo, MTT and colony forming assay were used to examine the effects of rhTNF-α on proliferation of HL-60 cells; AO/EB (acridine orange - ethidium bromide) staining, Annexin -V flow cytometry analysis and TUNEL assay were used to detect apoptotic cells .为了研究重组人肿瘤坏死因子-α(recombinanthumantumornecrosisfactor-alpha,rhTNF-α)在体外及体内对人髓系白血病细胞株HL-60细胞的作用,应用MTT法和集落形成试验测定HL-60细胞的增殖抑制,采用AO/EB荧光染色法、流式细胞术和TdT酶介导的缺口末端标记(TUNEL)法检测凋亡细胞;利用HL-60细胞裸鼠异种移植瘤模型观察给药后瘤体重量、组织病理的改变,并采用透射电镜以及TUNEL法检测瘤组织细胞的凋亡。
2.Purpose:It was investigated that the biological activi t ies of rhG-CSF,rhGM-CSF and rhTNF-α were determined by MTT method.目的 :对MTT法测定重组人粒细胞集落刺激因子 (rhG CSF)、重组人粒细胞 /巨噬细胞集落刺激因子 (rhGM CSF)、重组人肿瘤坏死因子 (rhTNF α)等基因工程细胞生长因子生物学活性进行方法学研究。
4)Recombinant human tumor necrosis factor-α重组人肿瘤坏死因子-α
1.Recombinant human tumor necrosis factor-αinhibits implanted gastric cancer of node mice via enhancing expression of death associated protein 3;死亡相关蛋白3参与重组人肿瘤坏死因子-α抑制裸鼠胃癌移植瘤的生长
5)human tumor necrosis factor-α人肿瘤坏死因子-α
6)hTNFβ人肿瘤坏死因子β(hTNFβ)
延伸阅读
肿瘤坏死因子分子式：CAS号：性质：又称恶液质素(cachectin)，淋巴毒素(lymphotoxin；LT)。注射卡介苗短小棒状杆菌和酵母多糖等制剂，再以内毒素攻击在小鼠、大鼠和兔等多种动物的血清中出现的一种能引起肿瘤出血性坏死的活性成分。含有唾液酸和半乳糖胺的一种糖蛋白，分子量约150 000。根据其产生来源和结构不同，可分为TNF-α和TNF-β两类，前者有单核-巨噬细胞产生，后者有活化T细胞产生，现已有基因重组技术制备。两类TNF的基本生物活性相似，除具有杀伤肿瘤细胞外，还有免疫调节，参与发热和炎症的发生。大剂量TNF-α可引起恶液质，医疗上可单独或白细胞介素2联合用于治疗肿瘤。
