PC-1基因,PC-1 gene
1)PC-1 genePC-1基因
1.To investigate the potential role of PC-1 gene over-expression on prostate cancer progression, a metastasis and androgen independent prostate cancer cell line C4-2B was used, cell clones constitutively expressing PC-1, and their mock-transfected counterparts were constructed.建立稳定表达外源PC-1基因的人前列腺癌骨转移C4-2B细胞模型,初步探讨PC-1基因表达对前列腺癌发展的影响。
2.BACKGROUND & OBJECTIVE: PC-1 gene is highly expressed in C4-2 cell line, an androgen-independent and aggressive prostate cancer cell line, but lowly expressed in LNCaP cell line, an androgen-dependent prostate cancer cell line.背景与目的:PC-1基因在雄激素非依赖和高转移能力的前列腺癌C4-2细胞中高表达,在雄激素依赖及不转移的前列腺癌LNCaP细胞中低表达。
3.Objective: To study the effect of PC-1 gene knockdown on the biological action of prostate cancer cell line C4-2.目的:研究用RNA干涉技术(RNAi)稳定抑制PC-1基因表达对前列腺癌细胞C4-2生物学行为的影响。
英文短句/例句

1.A Study of the Correlation between Gene Polymorphism of PC-1 and MTHFR Gene and Neural Tube Defects;PC-1基因、MTHFR基因多态性与神经管畸形关系的研究
2.RNAi Suppresses PC-1 Gene Expression in NIH3T3 and C4-2 Cells;RNA干涉抑制NIH3T3和C4-2细胞中PC-1基因表达的实验研究
3.Relationships between the K121Q Polymorphism of the PC-1 Gene and Obesity and Type 2 Diabetes;PC-1基因K121Q多态性与2型糖尿病及肥胖相关性的研究
4.Construction of PC-1 Transgenic Mouse Model and Researches on Function of PC-1 Related Gene FilaminA;PC-1转基因鼠模型构建及相关基因FilaminA功能研究
5.Researches on Function and Regulation Pathway of Prostate Cancer Related Gene PC-1;前列腺癌相关基因PC-1功能研究及其调控通路初探
6.Study on Association between Gestational Diabetes Mellitus and PC-1, PPARγ_2 Gene Polymorphisms;妊娠期糖尿病与PC-1,PPARγ_2基因多态性的相关性研究
7.The Inhibitory Effects of SiRNA Expression Vector on the Expression of Survivin Gene of Prostate Cancer PC-3 Cell;RNAi对前列腺癌PC-3细胞survivin基因表达的抑制作用
8.Silencering A20 Gene Expression in Prostate Cancer Cells PC-3 by Vector-Based RNAi;siRNA沉默前列腺癌细胞PC-3中A20基因的实验研究
9.gene transplantationph.1. 基因移植
10.Serum PC Ⅰ, PC Ⅲ, TIMP-1 and Target Organs Damage in Essential Hypertension;血清PC Ⅰ、PC Ⅲ、TIMP-1和原发性高血压靶器官损害
11.The Effect of the Lentivirus-mediated RNA Interference Targeting Survivin Gene on the Growth of PC-3 Cells in Vitro and Vivo;慢病毒介导的survivin基因稳定干扰对PC-3细胞株体内外生长的影响
12.Study on siRNA Interference HER-2/neu's Expression of Prostate Cancer Cells Line PC-3M;siRNA干扰前列腺癌PC-3M细胞HER-2/neu基因表达的研究
13.The Effect of KLF6 Gene Recombinant Plasmid on Prostate Cancer Cell Line PC-3;转染抑癌基因KLF6对前列腺癌PC-3细胞作用的实验研究
14.Inhibition of Survivin Gene Expression in Prostate Cancer Cell Line PC-3 by Vector-based RNAi;RNAi抑制前列腺癌细胞PC-3中survivin基因表达的实验研究
15.Gene Expression Profile of Prostate Cancer PC-3 Cell Induced by NKX3.1NKX3.1诱导前列腺癌PC-3细胞基因表达谱的改变分析
16.Study on gene vaccine pcDNA3-gtfB by intranasal immunization in rabbits变形链球菌基因疫苗pc DNA3-gtfB鼻黏膜免疫家兔的实验研究
17.The Inhibitory Effects of Apple Juice on Growth of Human Prostate Carcinoma PC-3 Cells苹果汁对PC-3细胞生长及其相关基因表达的影响
18.Study of Neuregulin 1 Gene ExpressionNeuregulin 1基因表达研究
相关短句/例句

PC-1genePC-1基因
1.Expression and purification of murine PC-1gene in E.coli;小鼠PC-1基因在大肠杆菌中的表达和纯化
2.To study the effect of exogenous excessive expression of PC-1gene N terminus43amino acids to the growth of human prostate cancer cell line C4-2.结果获得了稳定转染PC-1基因N端43个氨基酸的前列腺癌细胞株,在该细胞株中外源PC-1蛋白N端43个氨基酸得到高表达,细胞生长速度较对照细胞加快了38%。
3.The eukaryotic expression vector pIRES2-PC-1-46was construc te d by inserting a599bp DNA fragment ,which consisted of the N-terminus46am ino acids sequence and its upstream untranslation region of human PC-1gene,in to the vector pIRES2.以人前列腺癌C4-2细胞基因组DNA为模板,扩增出PC-1基因N端编码46个氨基酸残基及其上游非编码区共599bp的DNA序列,将其正向克隆到真核表达载体pIRES2中,并在脂质体介导下,转染人乳腺癌细胞MCF-7,经G418筛选获得阳性单克隆,细胞扩大培养后,进行PCR和RT-PCR分析,检测外源PC-1基因在靶细胞中的整合与转录。
3)prostate and colon gene 1(PC-1)前列腺癌相关基因(PC-1)
4)PC genePC基因
5)PC BCK1 genePC BCK1基因
6)DLC-1 geneDLC-1基因
1.Inhibition of DLC-1 gene expression by RNA interference (RNAi) in colon cancer LoVo cell line;反义DLC-1基因对结直肠癌LoVo细胞增殖和细胞周期的影响
2.Promoter methylation and expression of DLC-1 gene in human colon cell lines;3种结肠癌细胞株中DLC-1基因的表达及其启动子区的甲基化状态研究
延伸阅读

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