1)Human Telomerase RNA人端粒酶RNA
1.Construction of a Highly Expressed New Type Retrovirus Expressing Human Telomerase RNA and its Impact on Hepatocyte Proliferation;高效表达人端粒酶RNA逆转录病毒的构建及其对肝细胞增殖的影响
2.Construction of a bait plasmid containing human telomerase RNA mutant in yeast three-hybrid system人端粒酶RNA突变体酵母三杂交诱饵质粒的构建
英文短句/例句
1.Construction of a bait plasmid containing human telomerase RNA mutant in yeast three-hybrid system人端粒酶RNA突变体酵母三杂交诱饵质粒的构建
2.Construction of Screening Model for Telomerase Inhibitors Contained Human Telomerase RNA Mutant含人端粒酶RNA突变体的端粒酶抑制剂筛选模型的构建
3.Advance of correlation between human telomerase RNA gene and tumor人端粒酶RNA基因与肿瘤的相关研究进展
4.Effects of the Retrovirus Vector Containing Retro-hTR Gene on Growth of SGC7901 Cell Line;逆转录病毒介导的反义人端粒酶RNA基因对胃癌细胞生长的影响
5.Detection of Genomic Amplification of Human Telomerase Gene (hTERC) in Cytologic Specimens in the Screening of Cervical Lesions人端粒酶RNA基因(hTERC)检测在子宫颈病变筛查中的应用
6.Construction of recombinant retroviral vector encoding antisense human telomerase RNA component编码反义人端粒酶RNA组分重组逆转录病毒载体的构建
7.Establishment of RNA Interference Targeting Against Human Telomerase Reverse Transcritase (hTERT) and Research for It's Biological Effects;靶向人端粒酶逆转录酶(hTERT)RNA干扰的建立及其生物学效应的研究
8.Inhibitory Effects of Oncolytic Adenovirus with hTERT Small Interference RNA on Proliferation of Human Cervical Cancer HeLa Cells溶瘤腺病毒介导RNA干扰人端粒酶逆转录酶抑制HeLa细胞生长
9.Effect of hTERT RNA interference on biological characteristics of colon carcinoma人端粒酶逆转录酶RNA干扰对结肠癌细胞生物学行为的影响
10.Telomerase Activity in Gastric Cancer and Effect of Telomerase Antisense RNA on the Malignant Phenotype of Gastric Cancer Cell Line SGC7901;端粒酶在人胃癌中的表达及端粒酶反义RNA对SGC7901胃癌细胞恶性表型的影响
11.Effect of siRNA by targeting the human hTERT gene on morphology in Hep-2 cells靶向人端粒酶小干扰RNA对人喉癌Hep-2细胞系形态学影响
12.Telomerase RNA Gene (TERC) and Recent Studies on Cervical Cancer端粒酶RNA基因(TERC)与宫颈癌研究进展
13.The effect of liposome-mediated telomerase antisense RNA on telomerase activity and cell proliferation of MCF-7 cells脂质体介导端粒酶反义RNA对人乳腺癌细胞MCF-7活性及增殖的影响
14.Study on the Effect of shRNA of chTR on Telomerase Activity of Cell端粒酶RNA亚基的shRNA对细胞端粒酶活性影响的研究
15.Effective Inhibition of Telomerase Activity in Breast Cancer Cell T47D by siRNA;小干扰RNA抑制乳腺癌T47D细胞端粒酶活性的研究
16.Inhibition of Mutant Template Human Telomerase RNA on HeLa Cell Growth端粒酶RNA亚基模板突变抑制HeLa肿瘤细胞的生长
17.Telomere and Telomerase--A New Juncture for People to Surmount Cancer;端粒与端粒酶——人类攻克癌症的新契机
18.Inhibitions of Telomerase Activity on K562 Cell Line by Plasmid-vector Directing RNAi Against hTERT;质粒介导RNA干扰靶向hTERT抑制K562细胞端粒酶活性的研究
相关短句/例句
Human telomeric RNA人类端粒酶RNA
3)human telomerase RNA(hTR)人端粒酶RNA(hTR)
4)antisense hTR (human telomerase RNA components) gene反义人端粒酶RNA
5)human telomerase RNA gene人端粒酶RNA基因
1.Advance of correlation between human telomerase RNA gene and tumor人端粒酶RNA基因与肿瘤的相关研究进展
6)telomerase RNA端粒酶RNA
1.Expression of human telomerase RNA in ameloblastoma;人端粒酶RNA在成釉细胞瘤中的表达
2.Aim:To explore the effects of human telomerase RNA(hTR) antisense oligodeoxynucleotide (ASODN) on the telomerase activity, cell apoptosis,and the expression of apoptosis inducing factor (AIF) of EC9706 cells.目的:探讨封闭端粒酶RNA功能区的反义寡核苷酸(hTR ASODN)对食管癌EC9706细胞端粒酶活性、细胞凋亡及凋亡诱导因子(AIF)表达的影响。
3.Objective To explore the expression of human telomerase RNA (hTR) component and telomerase reverse transcriptase (hTERT) mRNA in lesions of psoriasis vulgaris and their relationships with keratinocytes proliferation.目的探讨端粒酶RNA(hTR)和反转录酶(hTERT)在银屑病皮损中的表达情况以及它们与角质形成细胞增殖关系。
延伸阅读
端粒酶分子式:CAS号:性质:一种以逆转录的方式合成真核细胞中线性染色体端粒DNA的特殊酶。该酶的辅基为一特定的RNA,端粒DNA的合成必须依赖酶分子中的辅基RNA为模板,通过逆转录而完成,其自身携带RNA作为产物的模板是区别于一般由纯蛋白组成的逆转录DNA聚合酶的主要特征。在逆转录时需要一个DNA引物,以便从5′→3′方向添加端粒的重复序列。底物是脱氧核苷三磷酸(dNTPs)。如在四膜虫(tetraphymena)中,四膜虫端粒酶催化反应式如下:染色体-GGGGTTGGGGTT(DNA引物)+4ndGTP(dNTPs)+2nTTP(dNTPs)→染色体-GGGGTTGGGGTT(GGGGTT)n(四膜虫端粒DNA)+6n焦磷酸端粒酶的活性在胚系细胞、癌化细胞中活跃;在体细胞,尤其经多次分裂后的体细胞,其活性降低。该酶的活性也可能是多细胞器官限制其细胞增殖的一种机制之一。
