1)Oligonucleotide[英][,?liɡ?u'nju:kli?utaid,?,liɡ?u'nju:kli?utaid][美][,ɑl?ɡo'nukli?ta?d, -'nju-, ,ol?-]寡聚核苷酸
1.It was found that the presence of anamino-space modifying thymidine in anoligonucleotide interfered the transfer reactionof [γ-32 ̄P] ATP bv T_4 polynucleotide kinase.寡聚核苷酸内部和5′末端含有的氨臂修饰胸苷酸,能够明显地影响T_4多核苷酸激酶催化的[γ- ̄(32)P]ATP的转移反应。
2.Through chemical modifications on oligonucleotides, more functions of DNA had been exploited.用这些单体分别设计合成了10个dT_5寡聚核苷酸模型序列,研究了功能化单体在寡聚核苷酸合成中的稳定性,并提出了磷酸残基修饰寡聚核苷酸合成的合成策略。
3.Chemical Synthesis and Stability of Oligonucleotides Modified by Alkyl- or Alkoxy- on the Phosphonates;利用这些单体合成模型序列5′-dTTTxTT-3′,考察了单体及寡聚核苷酸序列在DNA/RNA合成条件下的稳定性,提出了固相合成含有烷基修饰磷酸残基的寡聚核苷酸序列裂解及脱保护条件。
英文短句/例句
1.Fluorescence quenching of TMR by guanosine in oligonucleotides寡聚核苷酸中鸟苷对四甲基罗丹明的荧光猝灭
2.Colorimetric detection of melamine using gold nanoparticles capped with oligonucleotides寡聚核苷酸标记纳米金可视化检测三聚氰胺
3.Antiviral effects of two antisense phosphorothioate oligodeoxynucleotides against Japanese encephalitis virus strain SA 14 in cultured BHK 21 cells反义硫代寡聚核苷酸对抗日本脑炎病毒的活性
4.Studies on the Interaction between Single-strand Oligonucleotide and Ginsenosides by Electrospray Ionization Mass Spectrometry利用电喷雾质谱研究单链寡聚核苷酸与人参皂苷的相互作用
5.Chemical Modifications on Oligonucleotides Based on the Active Sites of Serine Proteases;基于丝氨酸蛋白酶催化中心的寡聚核苷酸化学修饰研究
6.Study on Antitumor Drug Discovery and Development of Decoy Oligonucleitide with Transcription Factor as Target;以转录因子为靶的抗肿瘤药物DECOY寡聚核苷酸研究
7.Influence of NF-κB Decoy ODN on the Initiating Inflammatory Injury of Renal Allografts in the Rat;NF-κB诱捕物寡聚核苷酸对大鼠移植肾早期炎性损伤的影响
8.ANALGESIC EFFECT OF INTRATHECAL ANTISENSE OLIGODEOXYNUCLEOTIDE OF TLR3 ON RATS FOLLOWING SPINAL NERVE LIGATION鞘内注射TLR3反义寡聚核苷酸对脊神经结扎大鼠的镇痛作用
9.The Study of Gene Mutation and Alternative Splicing in Primary Hepatocellular Carcinoma Using DNA Sequencing and Oligonucleotide Chip;应用DNA测序和寡聚核苷酸芯片对原发性肝癌中基因突变及变位剪接的研究
10.Identification of Acute Leukemia-specific Genes and the Pilot Study of Molecular Class Discovery by Oligonucleotide Microarray;利用寡聚核苷酸芯片进行急性白血病疾病基因组检测及基因分型的初步研究
11.antisense oligodeoxynucleotide反义寡(脱氧)核苷酸
12.Studies on Polymethacrylate Nanoparticles as Carrier of Antisenes Oligonucleotides;聚甲基丙烯酸酯纳米粒作为反义寡核苷酸载体的研究
13.Advances in Application of GpG DNA in Allergic RhinitisCpG寡聚脱氧核苷酸应用于变态反应性鼻炎的研究进展
14.Antitumour effects of survivin antisense oligonucleotide carried by nano-high-polymer on colorectal cancer纳米高聚合物转导Survivin反义寡核苷酸对大肠癌的体内杀伤作用(英文)
15.Survivin antisense oligonucleotide mediated by polyamidoamine dendrimer induces apoptosis of colorectal cancer cells聚酰胺纳米分子介导survivin反义寡核苷酸诱导结肠癌细胞凋亡(英文)
16.Study on the preparation of antisense oligodeoxynucleotide-PLGA nanoparticles and its properties反义寡核苷酸-聚丙交酯乙交酯纳米粒的制备及相关性质
17.SYNTHESIS OF OLIGONUCLEOTIDES WITH IMMOBILIZED RNase A用固定化牛胰核糖核酸酶催化合成寡核苷酸
18.allele specific oligonucleotide等位基因特异的寡核苷酸
相关短句/例句
oligonucleotides寡聚核苷酸
1.In this contribution,3'-alkythiol-capped oligonucleotides were successfully attached to the Ag nanoparticles.实验将3’端修饰巯基的寡聚核苷酸标记在纳米银粒子上,并基于银纳米粒子溶解后产生的Ag+对K2S2O8-luminol化学发光体系的催化作用,对标记寡聚核苷酸的银纳米粒子进行了定量检测。
3)oligodeoxynucleotide寡聚核苷酸
1.Separation of oligodeoxynucleotide by high performance anion exchange chromatography;用阴离子交换色谱法制备寡聚核苷酸
4)Oligonucleotide probe寡聚核苷酸探针
1.Objective: To evaluate the application of DNA fingerprinting map made by two synthesized and non-radioactive labeled oligonucleotide probes for genetic monitoring in inbred strain mice by comparing the stability, reproducibility and reliability of these two probes.目的:探讨用人工合成的两种非放射性标记的寡聚核苷酸探针制作的DNA指纹图在近交系小鼠遗传检测中的应用,并通过比较,分析两种探针的可靠性和稳定性。
5)oligodeoxynucleotide寡聚脱氧核苷酸
1.Establishment,optimization and application of a screening method for immunoregulatory oligodeoxynucleotides;免疫调节性寡聚脱氧核苷酸筛选方法的建立、优化和应用
2.Sequence designation and screening of novel immunoregulatory oligodeoxynucleotides;新型免疫调节性寡聚脱氧核苷酸的序列设计和筛选分析
6)Antisense oligodeoxynucleotide反义寡聚核苷酸
1.Influence of antisense oligodeoxynucleotide on pharmacological effects of opioid agonists: a review;反义寡聚核苷酸对阿片类药物药理作用的影响
2.Effects of antisense oligodeoxynucleotides against c-fos,bax,and p53 mRNAs upon apoptosis induced by lysophosphatidic acid in cultured cortical neuronsc-fos,bax和p53的反义寡聚核苷酸(ASOs)对溶血磷脂酸所致的培养小鼠大脑皮层神经元凋亡的影响(英文)
3.) application antisense oligodeoxynucleotide (AS-ODN) to induce prodynorphin (Pro-Dyn) mRNA and observed the degree of inflammatory edema after the formalin injection in rats to prove whether the quantity of dynorphin A in nerve centre could effect the degree of periphery inflammation.目的:利用鞘内注射前强啡肽mRNA的反义寡聚核苷酸,观察由福尔马林引起的大鼠后脚炎性水肿程度的变化,来证明脊髓背角中强啡肽(dynorphin,Dyn)A的量可能影响外周炎症反应的大小。
延伸阅读
聚腺苷酸脲嘧啶核苷酸 ,聚腺脲苷酸药物名称:聚腺脲苷酸英文名:Poly A:U别名: 聚腺苷酸脲嘧啶核苷酸 ,聚腺脲苷酸外文名:Poly A:U 适应症: 用于慢性乙型肝炎、流行性出血热、流行性乙型脑炎、病毒性角膜炎、带状皰疹、各种疣类和呼吸道感染等。 类别:干扰素诱导剂