1,5-苯并硫氮杂,1,5-benzothiazepine
1)1,5-benzothiazepine1,5-苯并硫氮杂
1.Eight α-maleimido substituted-β-lactam derivatives of 1,5-benzothiazepines were synthesized and their structures were confirmed by elemental analysis, IR, MS and 1H NMR specta.丁烯二酰亚氨基乙酰氯与1,5-苯并硫氮杂反应,合成了8个1,5-苯并硫氮杂-α-丁烯二酰亚氨基-β-内酰胺衍生物,用IR,MS,1HNMR和元素分析表征了产物的结构,用单晶X射线衍射法确证了产物的立体结构。
2.The 1,5-benzothiazepine as a special functional framework, has been widely used in synthetic drugs.1,5-苯并硫氮杂作为一个特殊的官能骨架,被广泛应用于药物的合成。
英文短句/例句

1.Synthesis and Crystal Structure of α-maleimidyl-β-lactam of 1,5-benzothiazepine1,5-苯并硫氮杂-α-顺丁烯二酰亚氨基-β-内酰胺的合成与晶体结构
2.Synthesis, Crystal Structure, Antimicrobial Activity and Structure Activity Relationship of 3-Ethoxycarbonyl-1,5-benzothiazepinesC(3)-酯基取代的1,5-苯并硫氮杂卓的合成、晶体结构及抑菌和构效关系的研究
3.Synthesis,Crystal Structure and Antibacterial Activities of α-Substituted β-lactam Derivatives of 1,5-Benzothiazepines1,5-苯并硫氮杂-α-取代-β-内酰胺衍生物的合成、晶体结构及其抑菌活性
4.Efficient synthesis of 1,5-benzodiazepines using gallium(III)triflate as a catalystGa(OTf)_3催化合成1,5苯并二氮杂
5.Synthesis of New Heterocyclic Compouds 1,5-Benzodiazepine Derivatives新型杂环化合物1,5-苯并二氮杂卓衍生物的合成
6.Synthesis and Crystal Structure of Novel Derivatives of 1,5-Benzo[b]thiazepine新型1,5-苯并硫氮衍生物的合成和晶体结构
7.Crystal Structure and Conformational Analysis of a Substituted Tricyclic 1,5 - Benzodiazepine.一个取代的三环1,5-苯并二氮杂(艹卓)的晶体结构和构象分析.
8.Synthesize and Study on the β-lactam Derivatives of 1,5-benzothiazepine;1,5-苯并硫氮杂卓-β-内酰胺衍生物的合成与研究
9.The Synthesis of 1, 5-Benzothiazepine, 1, 5-Benzodiazepine and Pyrazoline Derivatives Containing 2-Phenyl-1, 2, 3-triazole;含连三唑基的1,5-苯并硫氮杂卓,1,5-苯并二氮杂卓及吡唑啉类衍生物的合成
10.Synthesis of new 1,5-benzothiazepines containing 2-pheny1-1,2,3-triazol and their derivatives;新型含2-苯基-1,2,3-三唑基1,5-苯并硫氮杂及其衍生物的合成
11.Catalytic Synthesis of 1,5-Benzodiazepine Derivative by Carboxyl-functionalized Ionic Liquid羧基功能化离子液体催化合成1,5-苯并二氮衍生物
12.Synthesis of New [1,5]benzothiazepine Derivatives Containing 2-Phenyl-1,2,3-triazole;新型含1,2,3-三唑基1,5-苯并硫氮杂(艹卓)及其衍生物的合成
13.The Synthesis of 1, 5-Benzothiazepine and Pyrazoline Derivatives Containing Pyrazole;含吡唑基的1,5-苯并硫氮杂卓及吡唑啉类衍生物的合成
14.The Dissertation Submitted to Hebei Normal University for Master of Science Degree;新型1,5-苯并硫氮杂卓的合成及其抑菌活性的研究
15.Syntheses, Asymmetric Syntheses of 1,5-Benzothiazepion-α, α-Dimethyl-β-Lactam Derivatives;1,5-苯并硫氮杂卓-α,α-二甲基-β-内酰胺衍生物的合成及不对称合成
16.Synthesis of 2, 3/2, 5-dihydro-1, 5-benzothiazepines and the Search of Their Antimicrobial Activities;2,3/2,5-二氢-1,5-苯并硫氮杂卓类化合物的合成及其抑菌活性的研究
17.Studies on the Synthesis and Antimicrobial Activity of 1, 5-benzothiazepines Containing Amide Groups酰胺基-1,5-苯并硫氮杂卓类化合物的合成及其抑菌活性的研究
18.Effects of 1,5-Hexadiene and Benzene on the Desulfurization Property of NiY Zeolites1,5-己二烯和苯对NiY分子筛脱硫性能的影响
相关短句/例句

1,5-benzothiazepine1,5-苯并硫氮杂
1.Syntheses and Crystal Structure of 1,5-Benzothiazepine Derivatives Containing Pyrazole;含吡唑基的1,5-苯并硫氮杂衍生物的合成及晶体结构
2.Synthesis,Crystal Structure and Antibacterial Activities of α-Substituted β-lactam Derivatives of 1,5-Benzothiazepines1,5-苯并硫氮杂-α-取代-β-内酰胺衍生物的合成、晶体结构及其抑菌活性
3.Synthesis and Crystal Structure of α-maleimidyl-β-lactam of 1,5-benzothiazepine1,5-苯并硫氮杂-α-顺丁烯二酰亚氨基-β-内酰胺的合成与晶体结构
3)1,5-benzothiazepine1,5-苯并硫氮杂卓
1.Synthesis, Crystal Structure, Antimicrobial Activity and Structure Activity Relationship of 3-Ethoxycarbonyl-1,5-benzothiazepinesC(3)-酯基取代的1,5-苯并硫氮杂卓的合成、晶体结构及抑菌和构效关系的研究
2.1,5-benzothiazepine is a kind of compound which has important physiological activities.1,5-苯并硫氮杂卓是一类具有重要生物活性的七元杂环化合物,它的某些衍生物已经作为抗焦虑药物、催眠药物和心血管药物应用于临床,因此其合成、结构和药理活性的研究一直得到人们广泛的关注。
3.1,5-benzothiazepines are a kind of compounds with important biological activities, such as treating for neural and heart diseases.1,5-苯并硫氮杂卓(简称杂卓)是一类具有生理活性的化合物,其中一些化合物已作为治疗神经系统疾病以及心血管病的优良药物。
4)1,5-benzothiazepine1,5-苯并硫氮杂(艹卓)
5)1,5-Benzodiazepin-2-one1,5-苯并二氮杂酮
6)1H-1,5-benzodiazepines1,5-苯并二氮杂卓
1.Progress in the Synthesis of 1H-1,5-benzodiazepines;1H-1,5-苯并二氮杂卓的合成研究进展
延伸阅读

顺-(+)-5-[(2-二甲氨基)乙基]-2-(4-甲氧基苯基)-3-乙酰氧基-2,3-二氢-1,5-苯并硫氮杂卓-4(5H)-酮盐酸盐分子式:C22H26N2O4S·HCl分子量:450.98CAS号:33286-22-5性质:白色结晶或结晶性粉末。熔点187-188℃。易溶于水、甲醇、氯仿,难溶于无水乙醇,不溶于苯。无臭,味苦。制备方法:由2-氨基硫酚与对甲氧苯基环氧丙酸乙酯缩合得2-(4-甲氧基苯基)-3-羟基-1,5-苯并硫氮杂 -4(5H)-酮。再经酰化、与二甲氨基氯乙烷缩合、成盐制得硫氮卓酮。用途:钙通道阻滞药,用于室上性心律失常、心绞痛、老年人高血压等。本品为冠脉扩张药,对心绞痛有效。用于运动性绞痛及陈旧性心肌梗塞引起的心绞痛治疗。本品对雌小鼠口服LD50为640毫克/公斤,雄大鼠口服LD50为560毫克/公斤。