1)O-methylsinomenineO-甲基青藤碱二醛
1.Sinomenine (1) was O-methylated under Mitsunobu conditions to give O-methylsinomenine (2), which was converted into O-methylsinomeninedialdehyde (5) through a procedure of acid hydrolysis, boro-hydride reduction and thereafter oxidation with NaIO4.对青藤碱进行Mitsunobu甲基化反应,得到O-甲基青藤碱(2);2经过酸性水解、硼氢化还原以及高碘酸钠氧化开环得到O-甲基青藤碱二醛(5);在哌啶存在下对5进行羟醛缩合反应,区域选择性地闭环生成具有(+)-C-normorphinan骨架的化合物(8S,12S,13R)-6,7-didehydro-3,4-dimethoxy-16-methyl-C-normorphinan-7-carboxaldehyde(7);经过以上五步反应,7的总收率约35%。
2)benzoyl sinomenine苯甲酰青藤碱
1.Anti-inflammatory and analgesic effects of benzoyl sinomenine;苯甲酰青藤碱的镇痛抗炎作用
3)11α,12β-di-O-2-methylbutyryl-tenacigenin B11α,12β-二-O-2-甲基丁酰基-通光藤苷元B
1.Their structures were identified as 11α,12β-di-O-2-methylbutyryl-tenacigenin B (Ⅰ),11α-O-2-methylbutyryl-12β-O-acetyl-tenacigenin B (Ⅱ),tenacissoside H (Ⅲ),and marsdenoside A (Ⅳ),respectively.结果从通光藤的70%乙醇提取物中分离得到了4个C21甾体化合物,分别鉴定为11α,12β-二-O-2-甲基丁酰基-通光藤苷元B(Ⅰ)、11α-O-2-甲基丁酰基-12β-O-乙酰基-通光藤苷元B(Ⅱ)、通光藤苷H(Ⅲ)和marsdenosideA(Ⅳ)。
4)elegreen甲基柑青醛
5)sinomenine[,sain?u'meni:n]青藤碱
1.Preparation of sinomenine gel and its skin penetration test in vitro;青藤碱凝胶剂的制备及体外渗透性能研究
2.Determination of Sinomenine in Sinomenium acutum and Sinomenium Tablets by Capillary Electrophoresis with High Frequency Conductivity Detector;毛细管电泳高频电导法测定青风藤药材及制剂中青藤碱的含量
3.Quantitaive Determination of Sinomenine in “Zheng Qing Feng Tong Ning Tabellae”;高效薄层双波长扫描法测定正青风痛宁片中青藤碱的含量
英文短句/例句
1.Studies on Chemical Constituents of Sinomenium Acutum and Metabolites of Sinomenine in Rats;青风藤化学成分及青藤碱大鼠体内代谢研究
2.Study on the Effects of Caulis Sinomenii and Sinomenine on the Morphine-dependent Syndromes;青风藤及青藤碱抗吗啡依赖作用的研究
3.Determination of sinomenine in Caulis Sinomenii by nonaqueous capilary electrophoresis非水毛细管电泳法测定青风藤中青藤碱的含量
4.Content Determination of Sinomenine Hydrochloride in Sinomenine Hydrochloride External Applied Powder by HPLCHPLC法测定盐酸青藤外敷散中盐酸青藤碱含量
5.Structure Modification of Sinomenine and Their Anti-inflammatory Activity Research;青藤碱的结构修饰及其抗炎活性研究
6.Structural Modification of Rheumatoid Arthritis Drug Sinomenine;风湿性关节炎药物青藤碱的结构修饰
7.Induced biotransformation of sinomenine by o-phenylenediamine邻苯二胺诱导的青藤碱生物转化反应
8.Combined system of sinomenine hydrochloride sustained-release pellets盐酸青藤碱缓释组合微丸系统的研究
9.Study on Drug Release of Sinomenine External Application Sticking Powder in vitro盐酸青藤碱外敷贴散的体外释药研究
10.Synthesis of (+)-C-Normorphinan Analogs Starting from Sinomenine从青藤碱制备具有(+)-C-Normorphinan骨架的化合物
11.OBJECTIVE: To develop a preparation and quality control method for sinomenine gel.目的:探讨青藤碱凝胶的制备及质量控制标准。
12.Studies on effect of azone on percutaneous absorption of sinomenine gel in vitro月桂氮?酮对青藤碱凝胶剂的透皮吸收作用
13.The Preventive Treatment of Experimental Autoimmune Encephalomyelitis in Wistar Rats by Using Sinomenine and the Mechanism of Action;盐酸青藤碱对Wistar大鼠EAE的防治作用及机制探讨
14.Effects of Sinomenine on Function of Endothelial Cells in Medium with High Concentration of Glucose青藤碱对高糖状态下血管内皮细胞功能的影响
15.Effects of Snomenine on Transforming Growth Factor-β_1 in Diabetic Rat Kidney青藤碱对糖尿病大鼠肾脏TGF-β_1表达的影响
16.Mechanisms of the Apoptosis Induced by Sinomenine in Human Liver Cancer Cell Line HepG2青藤碱诱导人肝癌细胞HepG2凋亡机制的研究
17.HPLC determination of sinomenine in Fengshi Shengyao CapsulesHPLC法测定风湿圣药胶囊中青藤碱的含量
18.Effect mechanism of neuroprotection of Sinomenine on rats with cerebral ischemia-reperfusion青藤碱对缺血再灌注大鼠脑保护的作用机制
相关短句/例句
benzoyl sinomenine苯甲酰青藤碱
1.Anti-inflammatory and analgesic effects of benzoyl sinomenine;苯甲酰青藤碱的镇痛抗炎作用
3)11α,12β-di-O-2-methylbutyryl-tenacigenin B11α,12β-二-O-2-甲基丁酰基-通光藤苷元B
1.Their structures were identified as 11α,12β-di-O-2-methylbutyryl-tenacigenin B (Ⅰ),11α-O-2-methylbutyryl-12β-O-acetyl-tenacigenin B (Ⅱ),tenacissoside H (Ⅲ),and marsdenoside A (Ⅳ),respectively.结果从通光藤的70%乙醇提取物中分离得到了4个C21甾体化合物,分别鉴定为11α,12β-二-O-2-甲基丁酰基-通光藤苷元B(Ⅰ)、11α-O-2-甲基丁酰基-12β-O-乙酰基-通光藤苷元B(Ⅱ)、通光藤苷H(Ⅲ)和marsdenosideA(Ⅳ)。
4)elegreen甲基柑青醛
5)sinomenine[,sain?u'meni:n]青藤碱
1.Preparation of sinomenine gel and its skin penetration test in vitro;青藤碱凝胶剂的制备及体外渗透性能研究
2.Determination of Sinomenine in Sinomenium acutum and Sinomenium Tablets by Capillary Electrophoresis with High Frequency Conductivity Detector;毛细管电泳高频电导法测定青风藤药材及制剂中青藤碱的含量
3.Quantitaive Determination of Sinomenine in “Zheng Qing Feng Tong Ning Tabellae”;高效薄层双波长扫描法测定正青风痛宁片中青藤碱的含量
6)SIN[英][s?n][美][s?n]青藤碱
1.Suppressive effects of SIN on immunological function and cytokine production by T cells from the patients with SLE;青藤碱对红斑狼疮患者外周血T细胞的抑制作用及机制探讨
2.Objective To explore the molecular mechanism of immunosuppressive efficacy of alkaloid Sinomenine (SIN) against acute rejection following renal transplantation in rats.目的探讨青藤碱(SIN)对大鼠肾移植术后急性排斥反应免疫抑制作用的分子机制。
3.Objectives To evaluate the effects of the alkaloid sinomenine (SIN) on T cell proliferation and acute rejection in rat renal allografts.目的 探讨青藤碱 (SIN)对大鼠肾移植急性排斥反应 (AR)抑制作用的机制。
延伸阅读
[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式:C16H16ClN3O3S分子量:365.5CAS号:26807-65-8性质:暂无制备方法:暂无用途:用于轻、中度原发性高血压。