1)pK_apKa
1.A RBF-Network was applied to study the relationships between the pK_a of 13 kinds of inorganic binary hydride and the structural parameters.用径向基函数神经网络(RBF-Network)构建了一个无机二元氢化物酸性强度pKa与结构参数的非线性关联模型。
2.Using least square fitting, the observed walues of 13 single central inorganic hydride are correlated with their C, the equation is pK_a=-21.使用最小二乘法,将P区元素13种单中心无机氢化物的pKa实验值与其C关联,拟合得pKa=-21。
3.Finding a theoretical calculation method to obtain the accurate solvation free energy and pK_a value so as to verify or complement the experimental data has long been an important aspect for many theoretical chemists.寻找一种理论计算方法来验证和补充实验数据,得到较为精确的溶剂化自由能和pKa,是众多理论化学家长期以来研究的重要方向。
英文短句/例句
1.DFT calculation of pKa for some aromatic heterocyclics in DMSO Solution若干芳香杂环化合物在DMSO溶液中pKa值的密度泛函计算
2.Determination of ionization equilibrium constant for insulin-sensitizer rosiglitazone free base利用紫外分光光度法测定罗格列酮游离碱的pKa值
3.Prediction of pKa values of aromatic carboxylic acids based on multilinear regression analysis and support vector machine regression analysis基于多元线性回归及支持向量机回归分析对含苯基的羧酸类化合物pKa的预测(英文)
4.Molecular Topological Research on the Pka Values for Substituted Benzene Carbonic Acid;取代苯甲酸酸性Pka的分子拓扑研究
5.PKIB Inhibits cAMP-dependent Protein Kinase to Modulate Cell SenescencePKIB抑制PKA活性调节细胞衰老
6.Study on Selectivity of Inhibitor BD2 for PKA over PKC βⅡ抑制剂BD2对PKA与PKCβⅡ的抑制选择性研究
7.Effects of Bai Song Tablet on Regulating Expression of PKA and SYP in the Depression Model Rats;白松片对慢性抑郁模型大鼠PKA、SYP表达的影响
8.CCK Receptor and Anti-inflammatory Signaling Mechanism of cAMP-PKA Pathway Activated by CCK-8;CCK-8抗炎作用的受体及cAMP-PKA信号转导机制研究
9.Corticotropin-releasing Hormone Stimulating Corticotropin-releasing Hormone mRNA Expression Regulated by PKA Signal Pathway in Rat s Hypothalamic;CRH通过PKA途径调节大鼠下丘脑CRHmRNA表达的研究
10.Predicting the PKa of Pyridines Compounds with Ab-initio Quantum Chemical Description;用从头算量化参数预测吡啶类化合物的PKa值
11.The Molecular Topological Research on the Pka Values for Substituted Phoenols and the Pkb Values for Substituted Benzenne Amines;取代酚酸性PKa和取代苯胺碱PKb的分子拓扑研究
12.Effect of alternariol on PKA-CREB signal pathway in NIH3T3 cells互隔交链孢酚对NIH3T3细胞PKA-CREB信号通路的影响
13.The Hyperthropic Effect of UCN on Rat Neonatal Cardiomyocytes Mediated Via Activation of the PKA PathwayUrocortin致大鼠心肌细胞肥大由PKA信号通路介导
14.An Experimental Study on the Regulation Effect of the nm23-H1 Gene for PKA Signal Pathway of Lung Cancer Cell and Its Molecular Mechanism;Nm23-H1基因调控肺癌细胞PKA信号通路及其分子机理的实验研究
15.Effect of Apolipoprotein A-Ⅰ on Expression and Function of ATP-binding Cassette Transporter A1 Through PKA Signaling;载脂蛋白A-Ⅰ通过PKA信号途径影响ABCA1的表达与功能
16.PKA and Sch9 Regulate Budding Yeast Chronological Lifespan in Carbon Source Dependent Manner;不同碳源条件下PKA和Sch9对酿酒酵母时序寿命的调控
17.Effect of cAMP-PKA Signal Transduction Passway on the Mechanism of Preconditioning Cardioprotection;cAMP-PKA信号转导途径在预处理心肌保护机制中的研究
18.The Mechanism of PKA Signaling Pathway in Synaptic Plasticity after Cerebral Ischemia and Intervention Studies of AcupuncturePKA信号通路在脑缺血后突触可塑性中的作用及针刺干预研究
相关短句/例句
substituted phenolPKa值
1.On the elemental electronegative,bondid electron number and pz eletron number of atoms,one new molecular topological index (4X) is developed for research on the Pka values for 21 substituted phenols and the Pkb values for 22 substituted benzenne amines in this paper.结果表明,4X具有良好的结构选择性和性质相关性,可用于预测其它取代酚酸性PKa值和取代苯胺碱性PKb值。
3)pKa valuepKa值
1.OBJECTIVE The solubility in different solvents,the oil/water detached coefficient and pKa value of genistein were determined for the study of its absorption in vivo .目的 :测定染料木黄酮在不同溶剂中的溶解度、油 /水分配系数、pKa值。
2.The solubility in different solvents, the oil/water detached coefficient and pKa value of baicalin were determined by UV spectrophotometry for the study of its absorption in vivo.采用紫外分光光度法测定了黄芩苷在不同溶媒中的溶解度、油 /水分配系数、pKa值 。
3.The quantitative structure-property relationship(QSPR) method was performed to study the relationship between pKa values and electrotopological state indices of 45 organic compounds in DMSO.研究结果表明电拓扑状态指数能够有效地预测有机化合物的pKa值。
4)PKA mC αPKAmCα
5)cAMP/PKA/CREB signaling pathwayPKA-CREB
6)PKA expressionPKA表达
延伸阅读
PKA分子式：CAS号：性质：一种依赖cAMP的蛋白激酶。它由4个亚基组成，2个相同的调节亚基(R)和2个相同的催化亚基(C)。有两种同酶形式，I型和Ⅱ型，它们之间的催化亚基相同而调节亚基不同。四聚体全酶(R2C2)处于无活性状态，当4分子cAMP结合到两个调节亚基的结合部位时，无活性的四聚体介离，产生具有酶活性的游离催化亚基以及调节亚基与cAMP的复合物(R-cAMP)。PKA的作用底物包括膜蛋白、胞浆蛋白和核内蛋白，使多种蛋白质的丝氨酸或苏氨酸羟基的磷酸化，并由此引起一系列生化反应。
