1)differential expression protein差异表达蛋白质
1.The differentially expressed proteins were identified by matrix-assisted laser desorption/ionization quadrupole time-of-flight mass spectrometry(MALDI-Q-TOF MS),and a total of 18 differential expression proteins were successfully identified.对脊髓全横断损伤前后的大鼠脊髓全蛋白质进行双向凝胶电泳,借助PDQuest软件从中找出差异表达蛋白质点。
2.Objective To establish 2-dimensional polyacrylamide gel electrophoresis (2-DE) map from human nasal polyps and normal nasal mucosa, and to identify differential expression proteins of 2-DE map.目的:建立鼻息肉及鼻黏膜双向凝胶电泳(two-dimensional polyacrylamide gel electrophoresis,2-DE)图谱,鉴定差异表达蛋白质。
英文短句/例句
1.Stage and Gender Differential Proteome of Schistosoma Japonicum;日本血吸虫期别、性别差异表达蛋白质组研究
2.Identification and Analysis of Differentially Expressed Proteins of Gastric Adenocarcinomas Tissue;胃腺癌组织差异表达蛋白质的鉴定与分析
3.Differential proteomic analysis of the pancreas from diabete rat糖尿病大鼠胰腺差异表达蛋白质组分析
4.Differentially expressed proteins were identified using Liquid Chromatography/ Mass Spectrometry.对差异表达的蛋白进行质谱分析。
5.Proteomic and Genomic Analysis、Identification of Differential Protein and Gene Expression in Human Primer Gastric Cancer;胃癌蛋白质组与基因表达谱分析并差异蛋白质和基因的识别鉴定
6.The Differentially Expressive Research of Protein and Proteome of Gastrocnemius after Acute Exhaustive Exercise on Rats;急性力竭运动大鼠腓肠肌的蛋白质与蛋白质组差异性表达的研究
7.Research of Proteome Differential Expression in Rat Model of Liver-Qi Stagnation Syndrome;肝郁证模型大鼠蛋白质组差异表达研究
8.Study on Dialectically Associated Proteins of Liver-qi Stagnation Syndrome by Differentially Expressed Serum Proteome Analysis;肝郁证辨证相关血清蛋白质组的差异表达研究
9.Detection of Candidate Tumor Markers by Pancreatic Juice Proteomics in Pancreatic Carcinoma;胰液差异蛋白质基因在胰腺癌组织的表达检测
10.Differential Proteomic Analysis of Human Endometrial Carcinoma;子宫内膜癌蛋白质组的差异表达分析及意义
11.Differential Expression Analysis of Proteins under Verticillium Dahliae Stress in Cotton;棉花黄萎病菌胁迫条件下蛋白质表达差异分析
12.Study on the Protein Differential Expression of Yellow-and Black-seeded Oilrape (Brassica Napus);甘蓝型黑、黄籽油菜种皮蛋白质差异表达研究
13.Separation and Identification of Nuclear Matrix Proteins Expressed Differentially between Human Esophageal Immortalized and Carcinomatous Cell Lines;食管癌细胞差异表达核基质蛋白的分离与鉴定
14.Studies on Different Protein Expression during the Oocyte Meiosis Maturation;卵细胞成熟过程蛋白质表达差异性研究
15.Protein expression profile in blister beetle Mylabris calida Palla at the stage of cantharidin synthesis斑蝥素合成期的芫菁蛋白质表达差异分析
16.Differential proteomic analysis of thalamus in rats with diffuse axonal injury大鼠弥漫性轴索损伤后丘脑差异蛋白质表达
17.Proteomic Differential Expression of Rat Cardiomyocytes Induced by Hypoxic Postconditioning缺氧后处理诱导大鼠心肌细胞蛋白质差异表达
18.Effect of lightyellow sophora root on differential protein expression of Trichomonas vaginalis苦参对阴道毛滴虫蛋白质差异表达的影响
相关短句/例句
differential expression of proteome蛋白质差异表达
3)Differential proteins expression差异蛋白质表达谱
4)Differential protein expression profile蛋白质组差异表达谱
5)Differentially expressed protein差异表达蛋白
1.Analysis of differentially expressed proteins from hemolymph of Anopheles dirus infected and uninfected with Plasmodium yoelii;感染约氏疟原虫前后大劣按蚊血淋巴的差异表达蛋白分析
2.By using proteomics technique to separate and identify the differentially expressed protein between tumor cells and normal origin cells,more tumor specific markers will be found.应用蛋白质组学技术分离鉴定肿瘤细胞与常起源细胞之间的差异表达蛋白,可为寻找肿瘤的特异标志物,揭示肿瘤的发病机制,研究肿瘤转移、耐药机制及肿瘤治疗等提供更多的研究思路和理论依据。
6)expressed differential proteins表达差异蛋白
延伸阅读
表达谱差异分析表达谱差异分析(differential expression profiling)主要包括基因表达谱(gene expression profiling) 和蛋白质表达谱(protein expression profiling) 。大规模表达谱分析已经成为认识疾病分子机制的有利方法,在癌症研究等方面取得了一定的进展。成功的表达谱分析基于实验及其过程分析的有机结合。实验过程从关注的疾病开始,首先收集大量的疾病相关组织样本,样本数量可从10 多个到数百个,但必须足以对每一组织类型及个体差异进行比较分析,而且许多情况下不能仅简单地分为正常和疾病组织。例如,在对糖尿病的研究中,所收集的样本来自健康人、胰岛素耐受和糖尿病病人的不同试验阶段,如胰岛素治疗前后。样品还应包括其他器官的取材,以便进行基因表达的组织分布研究。为了便于对后来的实验数据进行分析管理,需采集并储存所有的组织样本和临床参数。接下来进行组织样本的处理,利用生物芯片(寡核苷酸芯片、cdna 芯片或全基因组芯片) 进行表达谱测定,并进行生物信息学分析。通常,表达谱的分析结果需进一步的实验加以证实。定量rt2pcr 是最灵敏的确证方法,该方法还可以将确证实验的范围扩大到原测组织以外的更广泛的组织和组织类型,揭示基因表达的组织分布情况。确证实验揭示了疾病相关基因。据此,可以进行进一步研究,探索这些基因的功能,开发新的治疗手段。例如,对于正常和疾病组织中表达有显著性变化的基因,可以进行新治疗靶点的鉴定和确定研究,或利用实验和分析工具研究分析其功能;对于疾病组织中活性升高的酶,可以当作前药活化酶进行鉴定研究。典型的表达谱能够显示疾病过程中有大量的已知基因表达的改变,而许多已知基因的代谢通路、表达产物酶学分类和蛋白质功能业已发表,将两者对照分析,可以鉴定出酶活性,选择其中可能成为前药活化酶的部分进行进一步研究;对于疾病特异的蛋白质,可以进行抗原表型分析,决定疫苗的开发策略。寻找差异表达基因的方法除芯片技术外,一些新的检测方法如差异显示pcr ( differential display pcr, dd－pcr) 、消减杂交( suppression subreactive hy bridization , ssh) 等也相继得到结合应用。
