MEK/MAPK通路,MEK/MAPK pathway
1)MEK/MAPK pathwayMEK/MAPK通路
1.AIM:To observe the effect of AngⅡ on retinal pigment epithelial cells(RPE) VEGF secretion and to explore the effect of lethal factor(LF) on VEGF secretion by inhibiting MEK/MAPK pathway.目的:体外观察血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)对视网膜色素上皮细胞(retinal pigmented epithelium,RPE)VEGF分泌的影响以及能否通过炭疽毒素致死因子(lethalfactor,LF)通过阻断MEK/MAPK通路对VEGF分泌的影响。
2)Ras/Raf/MEK/MAPK pathwayRas/Raf/MEK/MAPK通路
3)Ras/MEK pathwayRas/MEK通路
4)MEK/ERK PathwayMEK/ERK通路
1.Effect of Kuijieling Decoction on Gene Expression of ITF and MEK/ERK Pathway in Colonic Mucosa of Ulcerative Colitis Rats;溃结灵对溃疡性结肠炎大鼠结肠粘膜ITF表达及MEK/ERK通路的影响
英文短句/例句

1.Effect of MEK/ERK Pathway on the Sensitivity of TM-Induced Apoptosis in Gastric Adenocarcinoma Cell Lines;MEK/ERK通路对衣霉素诱导胃腺癌细胞凋亡敏感性的影响
2.Effect of Kuijieling Decoction on Gene Expression of ITF and MEK/ERK Pathway in Colonic Mucosa of Ulcerative Colitis Rats;溃结灵对溃疡性结肠炎大鼠结肠粘膜ITF表达及MEK/ERK通路的影响
3.The Molecule Mechanism of JWA Gene Involved in PKC Activated the c-Raf-MEK-ERK Signal Pathway;JWA参与PKC激活c-Raf-MEK-ERK信号通路的分子机制
4.EFFECTS OF ELECTROMAGNETIC RADIATION ON Raf/MEK/ERK SIGNALING PATHWAY IN RATS HIPPOCAMPUS电磁辐射对大鼠海马Raf/MEK/ERK信号通路的影响
5.Primary Study on the Ras/Raf/MEK/ERK Signal Transduction Mechanisms of Alzheimer's DiseaseRas/Raf/MEK/ERK信号传导通路在阿尔茨海默病中作用的初步研究
6.INHIBITION OF MEK UP-REGULATES THE EXPRESSION OF CHOP AND P53 UNDER ER STRESS阻断MEK/ERK上调内质网应激条件下CHOP和p53表达
7.The Research to the Mechanism of TGF-β Activate ERK Pathway;TGF-β激活ERK通路的机制探讨
8.Regulatory mechanisms of ERK signal transduction pathwayERK信号通路的信号转导调控机制
9.Effect of LeTx on angiotensin-induced VEGF expression by inhibiting MEK pathwayLeTx抑制MEK通路对体外血管紧张素诱导的VEGF分泌的影响
10.The Effect of Fluvastain on ERK Cascade in Bleomycin-induced Intersitial Pulmonary Fibrosis Rats Models;氟伐他汀对肺纤维化大鼠ERK信号通路的影响
11.The Effect of Apocynum Venetum Etract on ERK Pathway in Rat Myocardial Fibrosis罗布麻提取物对大鼠心肌纤维化ERK通路的影响
12.Regulatory role of the extracellular signal-regulated kinase signaling pathway in sensitivity of gastric cancer cells to cis-platinumERK通路对胃癌细胞顺铂敏感性的调节作用
13.Regulation of Melatonin on Expression of Myosin Light Chain Kinase in Endothelial Cell through the Pathway of ERK/MAPK in Atherosclerosis Model Rabbit褪黑素通过ERK/MAPK通路调控AS兔动脉内皮细胞MLCK表达
14.SHP-2 regulates PC12 cell survival and apoptosis in response to NGF via activation of ERK and JNKSHP-2通过ERK和JNK通路调节PC12细胞应对NGF的细胞生存和凋亡
15.TGFβ1 Upregulates Expression of MMP-2 and MMP-9 through ERK Signaling Pathway in Gastric Carcinoma CellsTGF-β1可通过ERK信号通路调节胃癌细胞MMP-2和MMP-9的表达
16.The Experiment Study of ERK Inhabitor on the Analgesic Effect and Mechanisms in CFA-induced Rat Pain Model;ERK通路抑制剂对完全弗氏佐剂致痛大鼠的镇痛效应及机制的研究
17.The Roles of Spinal ERK Signaling Pathway in Morphine Dependence and Withdrawal;脊髓水平ERK信号转导通路在吗啡依赖和戒断中的作用研究
18.The Role of ERK Signal Transduction in the Invading Process of Trophoblasts;ERK信号传导通路在滋养层细胞侵袭过程中的作用
相关短句/例句

Ras/Raf/MEK/MAPK pathwayRas/Raf/MEK/MAPK通路
3)Ras/MEK pathwayRas/MEK通路
4)MEK/ERK PathwayMEK/ERK通路
1.Effect of Kuijieling Decoction on Gene Expression of ITF and MEK/ERK Pathway in Colonic Mucosa of Ulcerative Colitis Rats;溃结灵对溃疡性结肠炎大鼠结肠粘膜ITF表达及MEK/ERK通路的影响
5)MAPK pathwayMAPK通路
1.Association of tumor metastasis suppressor genes of the MAPK pathway with invasive potential in uveal melanoma;MAPK通路中肿瘤转移抑制基因对葡萄膜黑色素瘤侵袭能力的影响
2.Objective:Observe the influence of MAPK pathway s signal transduction in RA synovial cell of experimental rabbits by moxibustion,and reveal the molecular signal mechanism of experimental RA by moxibustion.结果:造模组与正常对照组相比较,MAPK通路异常激活,Cyclin A1、p38 MAPK、ERK1、JNK1、N-ras等相关信号分子表达上调;艾灸组与造模组相比较,MAPK通路中异常激活的Cyclin A1、p38 MAPK、ERK1、JNK1、N-ras等相关信号分子的表达明显下调。
3.Besides, IL-22 can stimulate three main MAPK pathways: MEK-ERK, JNK/SAPK and p38 kinase pathway.此外,IL-22也可激活3条主要的MAPK通路:MEK-ERK、JNK/SAPK和p38激酶途径。
6)Ras/MAPK pathwayRas/MAPK通路
1.To investigate the biological roles of Ras/MAPK pathway in IL\|6\|induced M1 leukemia cells,the constitutive and inducible activation of Ras/MAPK pathway was blocked with MEK specific inhibitor PD098059 and the effects of PD098059 on IL\|6\|induced growth arrest and terminal differentiation of M1 cells were determined.为探讨 IL- 6在 M1细胞中激活 Ras/MAPK通路的意义 ,以 MEK激酶的特异性抑制剂PD0 980 59阻断 Ras/MAPK通路的组成型激活及诱导激活 ,观测 PD0 980 59对 IL - 6诱导的 M1细胞生长停止及终末分化的影响 。
延伸阅读

MEK 结构式为CH3CH2OCH3,分子量72.1。无色透明液体,有似丙酮气味。相对密度(20 ℃/4℃)0.8049,凝固点-86.9℃,沸点79.6℃,闪点(开口)-5.6℃,燃点515.6℃,粘度(25℃)0.42mPa·s,20℃时水中溶解度26.8%(wt),溶解度参数δ=9.3。溶于水、乙醇和乙醚,可与油混溶。易燃,蒸气与空气形成爆炸性混合物,爆炸极限1.81%-11. 5%(vol)。低毒,LD503980mg/kg,空气中最高容许浓度590mg/m3。 甲乙酮能溶解某些树脂和橡胶,是氯丁橡胶和聚氨酯橡胶的优良溶剂。