多耐药基因,MDR-1
1)MDR-1多耐药基因
2)Multi-drug resistance gene多药耐药基因
1.Relationship between multi-drug resistance gene polymorphism and blood concentration of ciclosporin in renal transplantation patients;肾移植中环孢素的血药浓度与多药耐药基因多态性的关系
2.Relationship between multi-drug resistance gene MDR1 and NF-kappa B in human drug-resistance erythroleukemia cells白血病耐药细胞中多药耐药基因MDR1与核转录因子κB的关系
3.Relationship between multi-drug resistance gene genetic polymorphism and blood concentration of tacrolimus in liver transplant patients肝移植中他克莫司的血药浓度与多药耐药基因多态性的关系
英文短句/例句

1.Study on multidrug resistance to tumor of cytokine-induced killer(CIK) cells after transfected with the multidrug resistance(mdr1) cDNA多药耐药基因转染的CIK细胞耐药性研究
2.THE EXPRESSION OF MDR1 GENE IN LEUKEMIC CELIS AMD ITS CLINICAL SIGNIFICANCE多药耐药基因在白血病细胞中的表达
3.Study of Mutidrug Resistance Gene Expression in Breast Cancer;乳腺癌多药耐药基因检测与临床应用
4.Expression and Reversal of Multi-drug Resistance Gene in Ovarian Cancer Cell卵巢癌多药耐药基因的表达及其逆转
5.Overexpression of MDR1 is associated with acquired tolerance to arsenic in L-02 cells多药耐药基因1与人肝细胞耐砷性关系
6.Association of a polymorphism in MDR1 C3435T with response to antiepileptic drugs treatment in intractable epilepsy难治性癫痫的耐药性与多药耐药基因MDR1C3435T多态性的相关研究
7.Relationship between multi-drug resistance gene MDR1 and NF-kappa B in human drug-resistance erythroleukemia cells白血病耐药细胞中多药耐药基因MDR1与核转录因子κB的关系
8.Clinical Application Research of MDR1C3435T Single Nucleotide Polymorphisms in Ovarian Cancer卵巢癌多药耐药基因MDR1C3435T多态性的临床应用研究
9.Reversion of Expression of the MDR1 and MRP in Human Tongue Carcinoma Cell Radiation-resistance Line by Antisense Oligonucleotides;多药耐药基因MDR1/MRP反义寡核苷酸逆转舌癌细胞放疗耐药性的研究
10.The Role of Upregulation of the Multidrug Resistance Gene in Drug-Resistant Gastric Carcinoma Cell胃癌耐药细胞中多药耐药基因上调的分子机制研究
11.Effect of hyperthermia and chemotherapy on CBRH-7919mdr MDR gene高温合并化疗对耐药性大鼠肝癌CBRH-7919细胞多药耐药基因的影响
12.Construction of Multidrug Resistance Gene-1 shRNA Vector and Research of Its Function for Human Resistance Leukemia Cells人耐药白血病细胞多药耐药基因-1小干扰RNA的构建及功能研究
13.Multi-drug Resistant Genes of Pseudomonas aeruginosa Clinical Strains多药耐药铜绿假单胞菌相关耐药基因研究
14.Multidrug Resistance-Associated Protein Gene Mediated Drug Resistance in Acute Leukemias;急性白血病多药耐药相关蛋白基因介导的多药耐药研究
15.The Verification of the Differentiated Gene Expression of Multi-drug Resistance in Ovarian Cancer;卵巢癌多药耐药差异表达基因的验证
16.Study on the Resistance Genes and Resistance Transmission Mechanism in Multidrug-resistant Enterococcus;多重耐药肠球菌耐药基因筛选及传播机制研究
17.Genotyping and Drug Resistance of Pseudomonas Aeruginosa in Respiratory Intensive UnitRICU多重耐药铜绿假单胞菌耐药基因特征研究
18.The research of multidrug resistant gene in salmonella enterica paratyphi A多重耐药甲型副伤寒沙门菌耐药基因的研究
相关短句/例句

Multi-drug resistance gene多药耐药基因
1.Relationship between multi-drug resistance gene polymorphism and blood concentration of ciclosporin in renal transplantation patients;肾移植中环孢素的血药浓度与多药耐药基因多态性的关系
2.Relationship between multi-drug resistance gene MDR1 and NF-kappa B in human drug-resistance erythroleukemia cells白血病耐药细胞中多药耐药基因MDR1与核转录因子κB的关系
3.Relationship between multi-drug resistance gene genetic polymorphism and blood concentration of tacrolimus in liver transplant patients肝移植中他克莫司的血药浓度与多药耐药基因多态性的关系
3)multidrug resistance gene多药耐药基因
1.Study on multidrug resistance gene expression between peripheral blood lymphocytes and tumor cells in hepatocellular carcinoma;肝癌外周血淋巴细胞和肿瘤细胞多药耐药基因表达的研究
2.Relationship between the expression and distribution of multidrug resistance gene and clinical effect in lupus nephritis;狼疮性肾炎多药耐药基因的表达分布与临床疗效关系的探讨
3.Clinical significance of multidrug resistance gene expression in advanced gastric cancer;进展期胃癌多药耐药基因表达的临床意义
4)MDR1多药耐药基因1
1.CYP3A5 and MDR1 gene polymorphisms is associated with pharmacokinetic variation of tacrolimus in renal transplant patients;细胞色素P450 3A5和多药耐药基因1基因多态性在肾移植患者他克莫司血药浓度监测中的应用
2.Objective To investigate the therapeutic efficacy and the possible action mechanisms of the recombinant adenovirus vector carrying antisense multidrug resistance gene 1(mdr1)targeting the reverse of α-fetoprotein(AFP+)positive MDR of HepG2R cells.目的探讨携带多药耐药基因1(multidrug resistance gene1,mdr1)反义RNA重组腺病毒载体靶向逆转甲胎蛋白阳性(AFP+)的肝癌多药耐药细胞HepG2R的疗效及作用机制。
3.Results The influences of independent variables on dependent variables in order of size were MDR1 3435(1)>MDR1 1236(1)>CYP3A5(2)>LDL>DBIL>Age>TC>HDL>L.结果9个自变量对因变量的影响从大到小依次为多药耐药基因1(MDR1)3435(1)、MDR11236(1)、细胞色素酶P450-3A5(CYP3A5)(2)、低密度脂蛋白胆固醇(LDL)、直接胆红素(DBIL)、年龄、总胆固醇(CHOL)、高密度脂蛋白胆固醇(HDL)、淋巴细胞(L);对方程内各自变量单独检验,CYP3A5(2)、MDR1 3435(1)、MDR1 1236(1)、DBIL、年龄、LDL、HDL对因变量有显著影响。
5)multidrug resistant gene多药耐药基因
1.Effect of fetal liver AFT024 cells on multidrug resistant gene 1 transfection efficiency and in vitro expansion of CD34~+ cells derived from umbilical cord blood;胎肝AFT024细胞对脐血CD34~+细胞体外扩增及多药耐药基因转染的影响
2.Multidrug resistant gene mdr1 expression in oral squamous cell carcinoma before and after chemotherapy;口腔鳞癌化疗前后多药耐药基因表达变化的分析研究
3.Purpose To determine the relationship between C3435T,a single nucleotide polymorphism (SNP) in exon 26 of the human multidrug resistant gene (MDR1) and cyclosporine (CsA) pharmacokinetic (PK) parameters among healthy Chinese volunteers.的 探讨多药耐药基因 (MDR1 ) 2 6外显子C3435T多态性与环孢素A(CsA)药动学特性间的关系。
6)MDR1多药耐药基因
1.Association of a polymorphism in MDR1 C3435T with response to antiepileptic drug treatment in ethic Han Chinese children with epilepsy;儿童癫癎对药物反应性与多药耐药基因MDR1C3435T多态性的相关性研究
2.Resistance of Cord Blood Nucleate Cells Transfected with Adenovirus-MDR1 Gene to Chemotherapeutic Drug;导入以腺病毒为载体多药耐药基因的脐血有核细胞对化疗药物的耐受性
3.Effects of genetic polymorphisms of CYP2C19,CYP3A5 and MDR1 on the pharmacokinetics of lansoprazole;细胞色素P450 2C19、3A5和多药耐药基因多态性对兰索拉唑代谢的影响
延伸阅读

抗药基因分子式:CAS号:性质:赋予宿主细胞对抗菌物质有耐受性的一类基因。通常由基因突变产生,如链霉素能与敏感菌株的核蛋白体30S小亚基结合,抑制细菌蛋白质合成。但是接触一定时间后,可因基因突变产生结构改变了的核蛋白体,使链霉素不能与之结合而失效。抗药基因还包括质粒所携带的抗药基因,常常是为特异分解此药物的酶编码的基因。带有抗药基因的质粒也称R因子或R质粒。R因子除能遗传子代外,还能通过噬菌体转导和细菌间的接合传布而产生新的耐药菌株。此外,耐药菌株溶解后释出的DNA还可重组进入敏感菌染色质中。