n-acetylpiperidine-4-carbonyl chlorideN-乙酰基哌啶-4-甲酰氯
1.Toluene is used as the solvent instead of sulfinyl chloride in the acyl chlorination to produce n-acetylpiperidine-4-carbonyl chloride with the yield of 97%.以4-哌啶甲酸为原料、醋酸为酰化剂,后期加入少量醋酸酐反应得到中间体N-乙酰基哌啶-4-甲酸,收率92%;在甲苯溶剂中进行酰氯化得目标产物N-乙酰基哌啶-4-甲酰氯,收率97%。
3)n-acetylpiperidine-4 carboxylic acidN-乙酰基哌啶-4-甲酸
1.4-Piperidinecarboxylic acid is used as the raw material and acetic acid as the acylating agent, followed by the addition of some acetic anhydride in the later stage to get an important organic intermediate n-acetylpiperidine-4 carboxylic acid in the yield of 92%.以4-哌啶甲酸为原料、醋酸为酰化剂,后期加入少量醋酸酐反应得到中间体N-乙酰基哌啶-4-甲酸,收率92%;在甲苯溶剂中进行酰氯化得目标产物N-乙酰基哌啶-4-甲酰氯,收率97%。
4)4-[1-hydroxy-1-(2,3-dimethoxyphenyl) methyl]-N-2-(4-fluorophenylethyl) piperidine4-(2,3-二甲氧苯硫基)-N-4氟苯乙基哌啶
5)trans-3-Ethoxycarbonyl-4-(4-flurophenyl)-N-methyl piperdine-2,6-dione反式-3-乙氧基甲酰-4-(4-氟苯基)-N-甲基哌啶-2,6-二酮
6)N-Carbethoxy-4-HydroxypiperdineN-乙氧羰基-4-哌啶醇
延伸阅读
[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式：C16H16ClN3O3S分子量：365.5CAS号：26807-65-8性质：暂无制备方法：暂无用途：用于轻、中度原发性高血压。
