1)Double knockout mice双基因敲除小鼠
1.To investigate the effects of EUK4010 on the neurodegenerative phenotypes of Presenilin-1/Presenilin-2 double knockout mice,10μg/g of body weight of EUK4010 was administrated on Presenilin-1/Presenilin-2 double knockout mice at 2—7 months and 6—11 months,respectively.为了研究本实验室筛选出的单体化合物EUK4010对Presenilin-1/Presenilin-2双基因敲除小鼠神经退行性症状的作用及机制,将EUK4010(10μg/g体重)分别作用于2月龄和6月龄的双基因敲除小鼠(dKO小鼠),通过组织学、实时荧光定量PCR及Western blot、行为学等方法发现该化合物对dKO小鼠的体重下降、脑室扩大、海马萎缩等有一定缓解作用,但对dKO小鼠认知行为的改变尚不明显。
英文短句/例句
1.Effects of inflammatory stress on LDL receptor expression in the liver of SRA/CD36 double knockout mice and its potential mechanisms炎症对SRA/CD36双基因敲除小鼠肝LDL受体表达的影响
2.Mechanisms of Cleft Palate Formation in Wnt5a Gene Knockout Mouse;Wnt5a基因敲除小鼠腭裂发生的机制研究
3.Study on Development and Mechanism of Arterial Calcification in Adiponectin-deficient Mice脂联素基因敲除小鼠血管钙化的研究
4.Deletion of Bmi-1 gene leads to skin aging in miceBmi-1基因敲除导致小鼠皮肤老化
5.GENOTYPE ANALYSIS OF FMR1 GENE KNOCKOUT MICE WITH POLYMERASE CHAIN REACTION采用PCR方法检测Fmr1基因敲除小鼠的基因型
6.Breeding,Reproducing,and Identifying for PAX-8 Gene Knock-out MicePAX-8基因敲除小鼠的饲养繁殖及基因型鉴定
7.Construction of the Mouse Enamel Matrix Serine Proteinase Gene Targeting Vector;小鼠釉基质丝氨酸蛋白酶基因敲除载体的构建
8.Study on Biological Properties of 1α Hydroxyrase Gene Knock-out Mice and Vitamin D3 Receptor Gene Knock-out Mice;1α羟化酶基因敲除小鼠和维生素D3受体基因敲除小鼠生物学特性的研究
9.Cloning of the Mouse Stat3/5 Locus and Generating of Stat5a/b Conditional Gene Knockout Mouse;小鼠Stat3/5基因座的克隆及Stat5a/b条件性基因敲除小鼠的制备
10.The corneal grafts in CD8 knock out mice were rejected at(28±3)days.Cd8基因敲除小鼠在(28±3)d时发生免疫排斥反应;
11.Effects of Aquaporin-4 Knockout on Airway Response in Mice;Aquaporin-4基因敲除对小鼠气道反应性的影响
12.Osteoblast-specific Knockout of the TGFBR2 Gene Results in Early Onset Osteoporosis in Mice成骨细胞特异性TGFBR2基因敲除小鼠发生骨质疏松
13.Inflammatory Stress Induce Insulin Resistance in the liver in the CD36 Knockout Mice炎症应激加重CD36基因敲除小鼠肝脏胰岛素抵抗
14.Electroacupuncture analgesia is enhanced in transgenic nociceptin/orphanin FQ knock-out mice孤啡肽基因敲除小鼠电针镇痛作用增强(英文)
15.Inhibition of nonalcoholic steatohepatitis by IL-22 in ApoE knockout miceIL-22对ApoE基因敲除小鼠脂肪肝抑制作用的研究
16.Behavioural comparision on FMR1 knockout mice at 30 days age in open field test30日龄FMR1基因敲除小鼠的旷场行为观察
17.p18~(INK4C) depletion aggravates cisplatin-induced acute kidney injury in micep18~(INK4C)基因敲除加重顺铂诱导的小鼠急性肾损伤
18.Lipid metabolism in lipoprotein lipase gene knockout heterozygous mice脂蛋白脂肪酶基因敲除小鼠脂代谢动态观察
相关短句/例句
SRA/CD36 double knockout miceSRA/CD36双基因敲除小鼠
1.Effects of inflammatory stress on LDL receptor expression in the liver of SRA/CD36 double knockout mice and its potential mechanisms炎症对SRA/CD36双基因敲除小鼠肝LDL受体表达的影响
3)Knockout mice基因敲除小鼠
1.[Objective] To observe the dynamic changes of bone mineral density at different bone sites of glucose-dependent insulinotropic polypeptide (GIP) receptor knockout mice (GIPR-/- mice) and to explore the possible effects of GIP on bone turnover in mice.【目的】观察葡萄糖依赖性促胰岛素多肽(GIP)受体基因敲除小鼠(GIPR-/-小鼠)不同部位骨密度的动态改变。
4)Cx43 gene knockout miceCx43基因敲除小鼠
5)Nurr1 knock-out(Nurr1+/-) miceNurr1基因敲除小鼠
6)gene knockout mice基因敲除小鼠
1.Objective To observe the effect of Zhixinkang Capsule (ZXKC) on serum TNF-α和IL-1β of Apolipoprotein E (ApoE)-gene knockout mice.目的观察脂欣康胶囊对载脂蛋白E(ApoE)基因敲除小鼠血清肿瘤坏死因子α(TNF-α)和白细胞介素1β(IL-1β)的影响。
延伸阅读
除鼠磷205CAS：453-13-4分子式：C3H6F2O分子质量：96.08中文名称：鼠甘伏；1,3-二氟丙醇；甘氟；除鼠磷205；鼠甘氟；甘伏；伏鼠醇英文名称：1,3-difluoro-2-propanol；Geiftor；Glyfluor性状描述：与1-氯-3-氟丙醇-2的混合物。1,3-二氟丙醇-2，[453-13-4]，沸点127-128℃，相对密度1.244（20℃），折光率1.3800（20℃）；1-氯-3-氟丙醇-2，[453-11-2]，沸点146-148℃，相对密度1.300（20℃），折光率1.4360（20℃）；鼠甘伏能与水、乙醇、乙醚互溶，较易挥发，在酸性溶液中稳定，而在碱性溶液中能分解。生产方法：氯甲基环氧乙烷与二氟氢化钾在二甘醇中于160-170℃反应，所得粗品经减压蒸馏，再经常压蒸馏，即得。 原料消耗定额：氯甲基环氧乙烷1700kg/t、二氟氢化钾1000kg/t、二甘醇1920kg/t。用途：主要用于野外灭鼠，尤其适于草原牧区。用含0.05-0.2%有效成份的药液，每亩30g，可杀除鼠兔和其他害鼠；防治黑线姬鼠，大仓鼠等害鼠，0.5、1.5%毒饵，10×5平方米放一堆,每堆10g；配制成含0.5%有效成分的大麦毒饵，投入鼠穴，效果更好。
