1)intracellular calcium concentration细胞内钙浓度
1.Especially, it remains to be clarified whether nicotinic acetylcholine receptors (nAChRs) are involved in the Aβ-induced elevation of intracellular calcium concentration ([Ca2+]i).然而,Aβ导致钙超载的机制,尤其是Aβ所致的细胞内钙浓度([Ca2+]i)升高是否与烟碱受体相关尚需进一步研究。
英文短句/例句
1.Effects of Lanthanum on Cell Multiplication and Intracellular Free Ca~(2+) Concentration in Primary Cultured Astrocytes of Rats镧对星形胶质细胞增殖能力和细胞内钙浓度的影响
2.Effects of Toosendanin on Calcium Channel, Intracellular Free-Ca～(2+) Concentration and Ca～(2+)-sensitivity of Neurotransmitter Release Machinery;川楝素对钙通道细胞内钙浓度和神经递质释放装置钙离子敏感性的影响
3.Role of Hypoxia on Intracellular Ca~(2+) Concentration in Pulmonary Venous Smooth Muscle Cells (PVSMC) Isolated from Rat Distal Pulmonary Veins低氧对大鼠远端肺静脉平滑肌细胞内钙浓度的影响及机制
4.Meanwhile the intracellular free calcium concentration was increased.细胞凋亡的同时细胞内游离钙浓度升高。
5.The concentration ofcalcium was assessed by ACAS (adherent cell analysis and sortingcytorneter).用粘附式细胞仪测定细胞内钙离子浓度；
6.Effect of Static Magnetic Field on Intracellular Calcium Concentration of Rat Osteoblast Cell;静磁场对鼠成骨细胞内钙离子浓度的影响
7.Effects of Grape Procyanidins on the Concentration of Intracellular Calcium in Hepatocytes;葡多酚对肝细胞内钙离子浓度的影响作用研究
8.The Effect of Stable-weak Magnetic Field on Intracellular Ca~(2+) Concentrations in Leukemia Cells;弱恒磁场对白血病细胞内钙离子浓度的影响
9.Time-frequency Analysis on Variation of Intracellular Free Calcium Concentration细胞内自由钙离子浓度变化的时-频分析
10.Effect of theaflavin on intracellular free calcium concentration in rat ventricular myocytes茶黄素对大鼠心室肌细胞内游离钙浓度的影响
11.The Alteration of the Concentration of Calcium in the Phagocytic Process of Human Pigment Epithelium Cells;人视网膜色素上皮细胞吞噬过程中细胞内钙离子浓度的变化
12.Xihuangwan induce Bel-7402 cell apoptosis the change of intraedlular-free calcium level in the process西黄丸诱导Bel-7402细胞凋亡及其细胞内钙离子浓度的变化
13.Effects of 8-Methoxypsoralen on intracellular [Ca~(2+)]i and cytoskeleton actin organization in human melanocytes in vitro8-甲氧沙林对黑素细胞内游离钙浓度及细胞骨架蛋白形成的影响
14.The Effect of Low-intensity Laser Irradiation on the Intracellular Calcium Concentration and Immunocompetence of Macrophages;低强度激光照射巨噬细胞对胞内自由钙浓度及其免疫活性的影响
15.Correlation Reseach of Concentration Diversity of Intracytoplasm Calcium Ion and Cell Apoptosis in Neuron;神经元胞浆内钙离子浓度变化和细胞凋亡相关性的研究
16.Influences and Mechanisms of Advanced Glycation End Products on Cytosolic Free Calcium Concentration in Cultured Neonatal Rat Cardiac Myocytes.;晚期糖基化终产物对心肌细胞胞内游离钙浓度的影响及其机制
17.Effect of Hypertonic Solution on Free Calcium in Endothelial Cells Suffering from Hypoxia/reoxygenation;高渗液对缺氧/复氧内皮细胞内游离钙离子浓度的影响
18.Effect of hypertonic solution on free calcium in human umbilical vein endothelial cells suffering from hypoxia/reoxygenation高渗液对缺氧/复氧人脐静脉内皮细胞内游离钙离子浓度的影响
相关短句/例句
intracellular([Ca2+]i)细胞浆内钙浓度
3)intraerythrocytic calcium红细胞内钙浓度
4)calcium ionic concentration of hepatocyte肝细胞内钙浓度
5)intracellular free calcium concentration细胞内游离钙浓度
1.In this present study, the effects of ET 1 on intracellular free calcium concentration ([Ca 2+ ] i) and the underlying mechanisms were investigated in cultured neonatal rat myocardail cells loaded with fura 2/AM.实验用培养新生ＳＤ 大鼠心室肌细胞， 以Ｆｕｒａ２／ＡＭ 荧光指示剂负载检测心肌细胞内游离钙浓度（［Ｃａ２ ＋ ］ｉ） 的变化， 探讨内皮素１（ＥＴ１） 对［Ｃａ２ ＋ ］ｉ 的作用及其机制。
2.For mechanism studies,the intracellular free calcium concentration(i) in cultured cardiomyocy.AN-FmRNA的表达用Real-time PCR检测;用Fura-2/AM负载的培养心肌细胞检测细胞内游离钙浓度([Ca2+]i);一氧化氮试剂盒测定细胞上清液中一氧化氮(nitric oxide,NO)代谢物的含量,以探讨Rg1可能的作用机制。
6)[Ca~ 2+ ]_ i细胞内游离钙离子浓度
1.Cytotoxicity was evaluated by MTT assay, intracellular Rh123 retention was measured by flow cytometry, and cellular [Ca~ 2+ ]_ i was measured b.方法:将不同浓度的洛美利嗪与人红白血病细胞系K562及其耐药细胞系K562/A02(耐阿霉素)共孵育24、48或72小时,然后分别向细胞中加入阿霉素,采用MTT法检测细胞毒作用;以流式细胞术测定两种细胞系内罗丹明123的潴留以反映P-糖蛋白的外排功能;利用Fluo-3/AM检测细胞内游离钙离子浓度。
延伸阅读
细胞内钙稳态失调在细胞功能的调节中，ca2+可作为第二信使起着信号传导的关键作用，同时ca2+ 也是多种参与蛋白质、磷脂和核酸分解的酶的激活分子之一。正常情况下，细胞内钙稳态是由质膜ca2+转位酶和细胞内钙池系统共同操纵控制的。细胞损害时，这一操纵过程紊乱可导致ca2+内流增加，ca2+从细胞内储存部位释放与/或通过质膜逐出抑制，从而导致细胞内ca2+浓度不可控制的持续增加，细胞内ca2+ 浓度持续高于生理水平以上必然导致维持细胞结构和功能的重要大分子难以控制的破坏。而且这种持续增加将会完全破坏正常生命活动所必需的由激素和生长因子刺激而产生的短暂的ca2+浓度瞬变，危及线粒体功能和细胞骨架结构，最终激活不可逆的细胞内成分的分解代谢过程。毒物可在不同水平上干扰细胞信号的传递，导致细胞内ca2+ 对激素及生长因子的正常反应的丧失。另外，钙信号系统的异常活化也是毒物引起细胞死亡的一个重要机制。当前，细胞内钙稳态失调是细胞损害与机制研究方面最为热门的话题，大量证据表明，细胞钙的持续增高可能活化各种不同组织和细胞的毒性机理，因而曾被称为“细胞死亡的最终共同途径”。
