1)acetylation[?,seti'lei??n]乙酰化修饰
1.Constructions of Gcn5 shRNAs interfere the histone acetylation modification with stem cell differentiation;Gcn5基因shRNA的载体构建及其对干细胞分化中组蛋白乙酰化修饰的干扰作用
2.Objective To construct 7 shRNA plasmids targeted to Gcn5 and to explore their role on histone acetylation in regulating MSCs differentiation into cardiomyocytes.目的通过组蛋白乙酰化作用相关shRNA质粒转染5氮杂胞苷(5-azacytid ine,5-aza)诱导后不同时间段间充质干细胞心肌发育基因的检测,探讨乙酰化修饰在干细胞特化心肌样细胞转录调控中的作用。
3.As acetylation of proteins facilitates the expression of proapoptotic genes and induces the degradation of oncoproteins and antiapoptotic proteins, HDACi induce apoptosis by activating the apoptotic signal transduction pathways at transcription and posttranslation levels.组蛋白去乙酰化酶抑制剂(HDACi)是一类新的化疗药物,能够有效抑制组蛋白去乙酰化酶的活性,促进组蛋白及非组蛋白的乙酰化修饰,在转录和翻译后修饰水平调控肿瘤靶蛋白及凋亡相关蛋白的表达和降解,活化凋亡信号通路,诱导肿瘤细胞凋亡。
英文短句/例句
1.The Acetylation of Thymosin α1 is Independent on RimL in Escherichia coli胸腺素α1的乙酰化修饰不依赖于乙酰转移酶RimL
2.The acetylation of histone H4 during spermatogenesis精子发生过程中组蛋白H4乙酰化修饰
3.Study on Hydrolyzing and Modifying Brown Rapeseed Isolated Protein by Enzymes and Acetic Anhydride褐变菜籽分离蛋白质酶水解及乙酰化修饰研究
4.Roles of Chromosome Acetylation and Deacetylation in Hsp Gene Expression in Drosophila果蝇中染色体乙酰化与去乙酰化修饰及其与热休克基因表达的关系
5.Study on Histone Acetylation Modification Mechanism of MSCs Differentiating into Cardiomyocytes;间充质干细胞特化心肌细胞中的组蛋白乙酰化修饰
6.Research on Histone Acetylation Mechanisams of Regulating the Process of MSCs Specially Differentiating into Cardiomyocytes;间充质干细胞特化心肌细胞的组蛋白乙酰化修饰调控机制
7.Role of Histone Acetylation in Reprogramming of Mouse Embryonic Genome after Nuclear Transfer;组蛋白乙酰化修饰对小鼠核移植胚基因组重编程的调控
8.Changes in Histone Acetylation during Oocyte Growth in Old Mouse;老龄小鼠卵母细胞发育过程中组蛋白乙酰化修饰的改变
9.Construction and Histone Acetylation Modifications of Cashmere Goat-Bovine Interspecies Reconstructed Embryos;绒山羊—牛异种核移植胚胎的构建及其组蛋白乙酰化修饰的研究
10.Proteomics Research on Serine/threonine and Lysine-acetyalted Proteins of Mouse Liver小鼠肝脏中丝氨酸、苏氨酸和赖氨酸乙酰化修饰的蛋白质组学研究
11.Modulation of Caspase expression by up-regulating histone acetylizad level with VPA应用VPA调节组蛋白乙酰化修饰对肿瘤细胞Caspase的影响
12.The Therapeutic Effect of Tripeptide Tyroservatide (YSV) on Lung Carcinoma and Its Mechanism by Affecting Histone Acetylation;三肽化合物酪丝缬肽（YSV）对肺癌的治疗作用及影响组蛋白乙酰化修饰的机制研究
13.Molecular Mechanisms of Histone Acetylation Modification in Regulation of Hsp Gene Expression and Lifespan in Drosophila Melanogaster组蛋白乙酰化修饰调控果蝇热休克基因表达和寿命的分子机制研究
14.Synthesis and Anti-bacterial Activity of α-C Alkyl Homologues of Octanoyl Acetal;辛酰乙醛α位C-烃化修饰及抗菌规律初探
15.The Enantio-differentiating Hydrogenation of Methyl Acetoacetate Over Tartaric Acid Modified Raney Nickel Catalysts with In-situ Modification原位修饰雷尼镍/酒石酸体系对乙酰乙酸甲酯的不对称催化加氢
16.Autoxidation of Monoterpenes with Oxygen Catalyzed by Co(acac)_2 Supported on Silica Functionalized Imidazole咪唑修饰硅胶负载乙酰丙酮钴(Ⅱ)催化分子氧氧化单萜烯研究
17.Electrocatalytic Oxidation of Formic acid on Porous Poly(N-acetylaniline) Electrode Modified with Pt and Pd Microparticles铂钯修饰聚N-乙酰苯胺膜电极对甲酸的电催化氧化
18.Electrocatalytic Oxidation of Methanol on Poly(N-acetylaniline) Film Modified by Pt and Co Particles铂钴修饰聚乙酰苯胺复合膜对甲醇的电催化氧化
相关短句/例句
histone acetylation组蛋白乙酰化修饰
3)phosporylation modification磷酰化修饰
4)pegylation聚乙二醇化修饰
1.Synthesis and pegylation of human parathyroid hormones (1-34);人甲状旁腺素(1-34)的合成与聚乙二醇化修饰
2.The covalent attachment of PEG (pegylation) to peptides and proteins can significantly improve their pharmacological and biological properties, such as shielding immunogenic epitopes, preventing degradation by proteolytic enzymes, increasing solubility, reducing renal filtration and altering biodistribution.蛋白质的聚乙二醇化修饰研究已取得较好的效果 ,多肽的聚乙二醇化修饰研究起步较晚 。
5)chemical modification化学修饰
1.Chemical modification the surface of lacquer film with titanium tetrachloride;四氯化钛在天然生漆膜表面的化学修饰
2.Study on pepsin′s chemical modification of nattokinase;胃蛋白酶对纳豆激酶的化学修饰研究
3.Polarize studies and chemical modifications of congo red compounds;刚果红分子的化学修饰及偏光性研究
6)α-modificationα-化修饰
延伸阅读
3-(N-乙酰乙酰)氨基-4-甲氧基乙酰苯胺分子式：暂无分子量：暂无CAS号：112854-88-3性质：暂无制备方法：暂无用途：暂无
