1)GABA_A receptorGABA_A受体
1.Lead compounds selection of inhibiting terpenoids of GABA_A receptor of houseflies;家蝇GABA_A受体萜类抑制剂先导化合物的筛选
2.GABA_A(γ-aminobutyric acid)receptor is a major inhibitory receptor at the central nervous system of vertebrates and insects,the structures and functions of GABA_A receptor have been explained preliminarily.近年来,GABA_A受体激动剂和拮抗剂的研究成为开发新型药物的热点之一,利用哺乳动物与昆虫GABA受体结合位点的区别可开发高效、安全的杀虫剂。
3.GABA_A receptors-mediated inhibition plays a pivotal role in regulating glutamatergic synaptic plasticity and circuit output.研究发现,增强GABA_A受体介导的抑制作用,是麻醉药损伤兴奋性突触传递长时程增强的一个重要原因,而且可能是全麻药相关记忆损伤的基础。
英文短句/例句
1.3D-QSAR Studies on GABA_A Receptor Noncompetitive Antagonists;GABA_A受体非竞争性拮抗剂的3D-QSAR研究
2.The Ionic Mechanism of Securinine as the GABA_A Receptor Antagnist;Securinine作为GABA_A受体拮抗剂的离子作用机制
3.Subunits Com bination of G A B A A Receptorin Central Nervous System;中枢神经系统中GABA_A受体的亚单位组合
4.Expression and Function of GABAA Receptor Subunits in Auditory SystemGABA_A受体亚单位在听觉系统的表达及作用
5.Effects of NO synthesis inhibition on pain threshold and on function of NMDA receptor and GABA_A receptor of rats.;一氧化氮合成阻滞对大鼠痛阈及脑NMDA受体、GABA_A受体功能的影响
6.Expression of γ-Aminobutyric Acid A (GABA) a Receptor Subunits and N-methyl D-aspartate (NMDA) Receptor Subunits in Rat Spiral Ganglion Neuron大鼠螺旋神经节神经元GABA_A受体、NMDA受体亚单位表达研究
7.Effects of Microinjecting GABA_A-receptor Agonist into the Tuberomamillary Nucleus on the Sleep-wakefulness Cycle in the Rat结节乳头体核微量注射GABA_A受体激动剂对大鼠睡眠—觉醒周期的影响
8.Expression of GABA_A Receptors Subunits in the Cochleas and Inferior Colliculus in the Postnatal Rats;大鼠耳蜗及下丘GABA_A受体生后表达规律的实验研究
9.Long-term Effects of Recurrent Neonatal Seizures on Expression of GABA_A Receptor α1, β2 and γ2 Subunits in the Rat Brain;新生大鼠反复惊厥对脑内GABA_A受体α1、β2和γ2亚单位表达的长期影响
10.Evidence for Involvement of GABA_A Receptors in Antinociceptive Effects of Diazepam in Mice;GABA_A受体参与地西泮引起的小鼠镇痛作用的机理研究
11.Effects of Convulsantdrugs on 3 H G A B A Bindingw ith G A B A A Receptor in Different Areas of Brain in Mice;不同致惊药物对小鼠不同脑区~3H-GABA与GABA_A受体结合的影响
12.Inhibitory Effects of Amiloride on the Current Mediated by Native GABA_A Receptors in Cultured Neurons of Rat Inferior Colliculus阿米洛利对大鼠下丘神经元上GABA_A受体的调控作用
13.Effect of GABA and GABA_A receptor activator on the proliferation of pancreatic cancer cells and the expression of MMP-2 in cancer cellsGABA及GABA_A受体激动剂对胰腺癌细胞增殖及MMP-2表达的影响
14.Exercise training improves GABA_A receptor mediated sympathetic outflow within the paraventricular nucleus in rats with heart failure运动训练改善心衰大鼠室旁核GABA_A受体介导的交感传出抑制作用
15.A laboratory study on the effect of X-ray on GABA and GABAA receptors in cerebral cortex of epileptic ratX线照射对实验性癫痫大鼠脑皮层GABA和GABA_A受体的影响
16.The GABA_A receptor-mediated inhibitory pathway increases the correlated activities in retinal ganglion cellsGABA_A受体抑制性通路增强视网膜神经节细胞活动的相关性(英文)
17.The Effects of Fentanyl and Combined with Propofol or Midazolum on GABA_A Receptor in Hippocampal Pyramidal Neurons of the Rats;芬太尼及其复合丙泊酚、咪唑安定对海马锥体神经元GABA_A受体功能的影响
18.Role of GABA_A Receptors in Pentobarbital-depressed Respiration of Neonatal Rat Medullary Slices in Vitro;新生大鼠延髓脑片标本GABA_A受体在苯巴比妥钠引起呼吸抑制中的作用
相关短句/例句
GABA_A receptorsGABA_A受体
1.Most of benzodiazepines effects are mediated by interaction with benzodiazepine binding site of GABA_A receptors.在热甩尾实验中,腹腔注射地西泮(1 mg/kg)显著地引起了小鼠甩尾潜伏期的延长,且这种延长作用能被提前腹腔注射氟马西尼(一种GABA_A受体上的苯并二氮结合位点的特异性拮抗剂),荷包牡丹碱(一种GABA_A受体的竞争性拮抗剂)和印方己毒素(一种氯离子通道阻断剂)所阻断。
3)GABAA receptorsGABA_A受体
1.In addition to modulation by a variety of structurally diverse agents that act allosteri-cally via distinct binding sites on the receptor complexes , there is another outstanding characteristic of the GABAA receptors: they are modulated by multiple endogenous agents.除了通过受体复合体上特有的结合位点接受多种结构不同的物质的变构调控外,GABA_A受体的另一个显著特点是受多种内源性物质如Ca(2+),三磷酸腺苷,蛋白激酶A,蛋白激酶C,酪氨酸激酶和钙调素依赖性蛋白激酶Ⅱ等的调控。
4)GABA_A/BZ receptorGABA_A/BZ受体
1.CoMFA and DISCOtech studies of 4-quinolone derivative agonists for the GABA_A/BZ receptor;GABA_A/BZ受体激动剂4-喹啉酮衍生物的DISCOtech及CoMFA研究
5)GABA_A Rα1GABA_A受体α1
6)GABAA Receptor proteinGABA_A受体蛋白
延伸阅读
GABA分子式:C4H9NO2分子量:103.12CAS号:56-12-2性质:熔点195-204°C。水溶性SOLUBLE。