蛋白转导域,protein transduction domain
1)protein transduction domain蛋白转导域
1.Recent progress in internalization mechanism of protein transduction domain;蛋白转导域内在化机制的研究进展
2.The cationic 11-amino acid fragment derived from human immunodeficiency type 1 (HIV-1) tat protein, termed TAT protein transduction domain, has proven to be an invaluable tool to deliver a wide variety of macromolecules across the plasma membrane and into intact tissues.TAT蛋白转导域是源自人类免疫缺陷病毒Tat蛋白的一段碱性氨基酸多肽,能够将与之共价连接的多肽、蛋白、核酸等生物大分子快速而高效地转导入细胞内部,在药物转运和疾病治疗等领域有着巨大的应用潜力。
3.Through the medium of protein transduction domain(PTD) composed by a small number of alkaline peptides, the functional proteins linked covalently with DNA, peptides, proteins or other macromolecules can across the membranes of mammalian cells, even the blood-brain barrier and transfer unconventionally that isn t like classical pathway.蛋白转导是近几年生命科学领域发现的一种独特现象,具有蛋白转导功能的蛋白通过几个短的碱性小肽组成的蛋白转导域(proteintransductiondomain,PTD)的介导,能将与其共价连接的DNA、多肽或蛋白质以及其他大分子物质通过非经典途径穿过细胞膜甚至血脑屏障,并在细胞间自由传递。
英文短句/例句

1.Advances in Study on HIV-Tat Protein Transduction DomainHIV-Tat蛋白转导域的研究进展
2.Prokaryotic Expression and Biological Activity of Poly-Arg Protein Transduction Domain-Apoptin Fusion Protein多聚精氨酸蛋白转导域-凋亡素融合蛋白的原核表达及其生物活性
3.Secretion Expression and Characterization of Human Mature Nerve Growth Factor with Protein Transduction Domain of HIV-Tat带有HIV Tat-蛋白转导域的人成熟神经生长因子的分泌表达及鉴定
4.Construction of SFV-replicon Vaccine Based on PTD Fused with HA of Influenza A (H5N1) Virus and Its Cellular Immune Response Induction基于蛋白转导域的人禽流感复制子疫苗的构建和诱导细胞免疫应答研究
5.The Study of the Transmembrane Activity of the PTD of Tat Protein Fused at the Carboxyl-terminus of Heterologous Protein;融合在外源蛋白羧基端的Tat蛋白转导结构域的跨膜递送作用研究
6.Mechanism for Cellular Internalization and Aapplication of the TAT Protein Transduction Domain;TAT蛋白转导结构域跨膜递送机理及其应用基础研究
7.Pax4 protein can be transduced into mammalian cells转录因子Pax4蛋白质转导功能的研究
8.Functional Analyses on Regulator of G Protein Signaling (RGS) Proteins in Arabidopsis Thaliana;拟南芥G蛋白信号转导调节蛋白(AtRGS1蛋白)功能研究
9.Proteomics Analysis Reveals Insight into the Mechanism of H-Ras-Mediated Transformation;H-Ras介导细胞转化的蛋白质组学分析
10.Studies on Protein Transduction of VP22 in CVI988 Attenuated Vaccine Strain of Marek's Disease Virus;MDV CVI988弱毒疫苗株VP22蛋白转导功能研究
11.Pro-Apoptotic Protein-BclGs Inhibits Ap-1 Activity Through Jab1;促凋亡蛋白(BclGs)的信号转导机制研究
12.Transformation of Gossypium Hirsutum Al-induced (GhAlin) Gene;棉花铝诱导蛋白基因(GhAlin)的遗传转化
13.Study on Protein Transduction and Immunogenicity of BCR/ABL Fusion Protein Mediated by Protein Transduction Domain;PTD介导BCR/ABL蛋白细胞转导及免疫原性的研究
14.The Signal Transduction Role of Ca~(2+)/Calmodulin-Dependent Protein Kinase Ⅱ in Cardiac RemodelingCa~(2+)/钙调蛋白依赖性蛋白激酶Ⅱ在心脏重构中的信号转导作用
15.Tat transduction peptide displayed on the nucleocapsid improved the baculovirus transduction of mammalian cells核衣壳蛋白VP39融合TAT转导肽对杆状病毒转导哺乳动物细胞的影响
16.Functional Analysis of a Novel Family of Protein Kinases;一种新型蛋白激酶信号转导系统的初步研究
17.Screening for the Signal Transduction Molecule-PAK4 Binding Proteins by Yeast Two Hybridization;信号转导分子PAK4相互作用蛋白质的筛选
18.The Signal Transduction Pathways of Imidazoline-1 Receptor Candidate Protein;咪唑啉1型受体候选蛋白信号转导的研究
相关短句/例句

Protein transduction domain蛋白质转导域
1.Aim:To observe the protective effects of protein transduction domain-kallikrein(PTD-kallikrein)on neurons incubated in condition of oxygen-glucose deprivation(OGD)/recovery,and to explore the protective mechanism.目的:观察蛋白质转导域-激肽释放酶(PTD-kallikrein)对缺糖、缺氧(OGD)再复糖、复氧培养的神经元保护作用,探讨其可能的作用机制。
2.Protein transduction or protein therapy, as an important approach of disease therapy, is achieved through linking exogenous therapeutic proteins to the fragment of amino acid, termed as protein transduction domain, using the expression vector or chemical cross-linking method.蛋白质转导或蛋白质治疗是通过表达载体法或化学交联法将具有治疗作用的外源性蛋白质与称为蛋白质转导域的氨基酸片段相连,以非受体和非温度依赖的方式越细胞膜进入胞内达到治疗疾病的目的。
3)HIV-TatPTDHIV-Tat蛋白转导域
1.AIM: To introduce hepatitis B virus(HBV)targeted ribonu-clease into hepatocytes by using human immunodeficiency virus Tat protein transduction domain (HIV-TatPTD).目的:利用HIV-Tat蛋白转导域(proteintransductiondomain,PTD)高效的跨膜转导特性,探索将乙肝病毒靶向核糖核酸酶(targetedribonuclease,TR)导入肝细胞的新途径。
4)Protein transduction domain蛋白转导结构域
1.Recently, it has been found that the protein transduction domain has the ability of permeating cell membrane and can exert bioactivity by taking permeability cell membrane of macromolecular peptides into cells.近年来 ,人们发现蛋白转导结构域具有穿透细胞膜的能力 ,并能携带大分子肽类通透细胞膜进入细胞内发挥生物活性。
2.Protein transduction as a new biotechnology,was reviewed in the aspects of its discovery,structural and functional characteristics of its protein transduction domain(PTD),and the functional mec-hanism of PTD.综述了蛋白转导的发现、蛋白转导结构域(PTD)的结构组成特点、蛋白转导的作用特点、PTD的作用机理以及蛋白转导的应用前景等。
3.To construct a recombinant plasmid containing protein transduction domain(PTD) and brain derived neurotrophic factor(BDNF) fusion gene and express in E.构建含蛋白转导结构域(PTD)与脑源性神经营养因子(BDNF)融合基因的质粒,并在大肠肝菌中表达。
5)protein transduction domain(PTD)蛋白质转导域
1.OBJECTIVE A protein transduction domain(PTD) derived from the HIV TAT protein could benefit macromolecules across blood brain barrier(BBB).目的来源于人类免疫缺陷病毒(HIV)-I型编码的反式激活蛋白(TAT)中的蛋白质转导域(PTD),能介导生物大分子通过血脑屏障。
6)Protein transduction domain蛋白转导功能域
延伸阅读

脉心导敏 ,脉导敏,英他佐明,麦新导明药物名称:吗多明英文名:Molsidomine别名: 吗导敏;吗多明;吗斯酮胺;脉心导敏 ,脉导敏,英他佐明,麦新导明外文名:Molsidomine 特点: 脉导敏是一种属于亚胺类化合物,其作用与硝酸盐相似。舌下含服1毫克,2~4分钟起作用,可阻止心绞痛发作。口服一次可持续6~7小时,剂量每天3次,每次2毫克。副作用包括头痛、头胀、脸部发热感等,但不多见。 适应症: 防治心绞痛的发作。 用量用法: 口服:1次1~2mg,1日2~3次,发作时舌下含服:1次2mg。喷雾吸入:每次揿吸1~2次(相当于本品0.2~0.4mg),每日次数酌定。 注意事项: 1.一般不良反应可有头痛、面部潮红、眩晕等,停药后可自行消失。 2.低血压、青光眼病人忌用。 规格: 片剂:每片1mg、2mg。 气雾剂:每瓶含42mg(可揿吸200次左右)。 类别:非选择性钙通道阻滞剂||防治心绞痛药