1)differentially expressed genes差异表达基因
1.Analyses on the differentially expressed genes associated with murine double minute 2/p53 pathway in breast cancer;mdm2/p53通路相关的乳腺癌差异表达基因分析
2.Screening of differentially expressed genes in rat brain repeatedly exposed to+Gz;正加速度重复暴露大鼠脑差异表达基因的筛选
3.Cloning and screening of differentially expressed genes from the male gametophytes of Laminaria japonica Aresch;海带雄性配子体差异表达基因片段的克隆及筛选
英文短句/例句
1.Studies of Gene Differential Expression in Dictyostelium Discoideum Cells;盘基网柄菌细胞差异表达基因的研究
2.The differentiation expressed genes screening methods based on mRNA expression level基于mRNA水平的差异表达基因筛选技术
3.Investigation on Differential Expressed Genes in Bone Marrow between Tibetan and Han Ethnic Group;藏、汉族骨髓组织差异表达基因研究
4.Differentially Expressed Genes During Ripening of Persimmon Fruit;柿果实成熟期间差异表达基因的研究
5.Study on the Genes Differentially Expressed during Hepatocarcinogenesis;肝癌发生过程中差异表达基因的研究
6.Screening and Primarily Analysis the Differential Expression Genes Related to the Development of Goose Fatty Liver;鹅肥肝中差异表达基因的筛选及分析
7.The Verification of the Differentiated Gene Expression of Multi-drug Resistance in Ovarian Cancer;卵巢癌多药耐药差异表达基因的验证
8.Study on the Differentially Expressed Genes of Aged Kidney-Yang Deficiency Syndrome老龄肾阳虚证的差异表达基因谱分析
9.Searching for Differentially Expressed Genes by PLS-VIP Method利用PLS-VIP方法筛选差异表达基因(英文)
10.The Initial Study on CRC Differentiation-related Gene MAGEA3 and Differentiation-related CRC-EST1;大肠癌分化差异表达基因MAGEA3与分化差异表达CRC-EST1的初步研究
11.cDNA Microarray Screening of the Differentially Expressed Transcripts and Upregulation of SPARC in the Deafferented Hippocampus;去传入海马差异表达基因的筛选和SPARC表达
12.Screening of the Differentially Expressed Genes and Cystatin C Expression in the Deafferented Hippocampus;去传入海马的差异表达基因的筛选和Cystatin C表达
13.Cloning and Characterization of the Difference of Gene Expressed in Pig Hypothalamus猪下丘脑发育差异表达基因的分离、克隆与表达
14.Verification and Identification of Valuable Differentially Expressed Genes from Our Gastric Cancer cDNA Microarry Data;胃癌基因芯片差异表达基因的验证和筛选
15.The Influence on Express of Differentially Expressed Transforming Growth Factor β_2 Gene in Liver of Goose by Overfeeding;超饲养对鹅肝脏差异表达基因转化生长因子β_2基因表达的影响
16.Study on the SNPs and Expression Difference of Chicken Polydactyly Candidate Genes;鸡多趾候选基因的SNPs及表达差异研究
17.Lung Adenocarcinoma Migrating to Spine Associated Gene Defferent Expression Analysis;肺癌脊柱转移相关基因差异表达分析
18.Correlations between Maize (Zea Mays L.) the Differential Gene Expression and Heterosis;玉米基因差异表达与杂种优势的关系
相关短句/例句
differentially expressed gene差异表达基因
1.Detection of differentially expressed genes in human autosomal dominant polycystic kidney tissue;常染色体显性多囊肾组织差异表达基因的初步研究
2.Cloning of differentially expressed genes of eosinophils from asthmatic patients by suppression subtractive hybridization;应用抑制消减杂交克隆支气管哮喘病人嗜酸细胞差异表达基因
3.Screening of differentially expressed genes in the regeneration of injured spinal cord of neonatal rats;新生大鼠脊髓损伤修复差异表达基因的筛选
3)differential expression gene差异表达基因
1.Investigation of the differential expression genes of K562 cells induced by arsenic trioxide with microarray;应用基因芯片研究As_2O_3诱导K562细胞前后差异表达基因
2.Effects of the treatments of the repeat measurements on the selection of differential expression genes in cDNA microarrays;cDNA芯片中重复检测值的处理方法对差异表达基因选择的影响
3.In order to understand differential expression gene in Alhag sparsifolia root,the research was studied by Medicago Genome Array(61278 probes) of Affymetric company.以新疆耐盐豆科植物疏叶骆驼刺(Alhagi sparsifolia)为研究对象,对其种子萌发耐盐性进行了研究;利用Affymetrix公司的截型苜蓿基因组芯片(Medicago GenomeArray),包括61278个探针,检测疏叶骆驼刺幼根在220mmol/LNaCl胁迫处理0h和24h的差异表达基因,利用GO功能注释对所获得的差异表达基因进行分析,结合PCR技术设计引物对探针所对应的功能基因在疏叶骆驼刺中进行克隆;建立了疏叶骆驼刺的茎段离体快繁体系,为苗期耐盐性测定奠定基础。
4)Differential Expression genes差异表达基因
1.Identifying differential expression genes based-wavelet transform & SAM methods;基于小波变换-SAM方法的差异表达基因筛选研究
2.Objective: To identify the differential expression genes of the regenerating somatosensory cortex after the spinal cord of the newborn rats was hemi-sectioned, to clone them and analysis their relationship with regeneration.方法:新生大鼠脊髓双侧半横断后即刻单侧胚胎脊髓移植,术后3天用抑制性消减杂交技术筛选大鼠双侧运动皮层神经元差异表达基因,构建差减cDNA文库,通过蓝白斑实验和cDNA斑点杂交验证差异表达基因真阳性克隆,测序分析。
3.In order to screen the specific genes to high altitude hypoxic adaptation , the SSH cDNA library of differential expression genes in.本研究以藏汉族骨髓组织为材料,采用抑制削减杂交技术和基因芯片技术对藏汉族骨髓组织差异表达基因进行筛选,利用定量RT-PCR方法对部分基因进行验证,应用生物信息学方法对差异表达基因进行分析。
5)Differential expressed gene差异表达基因
1.To study genes related with IL 6 effect, here a simple and rapid PCR based protocol is utilized to detect and isolate cDNA fragments of the differential expressed genes between the IL 6 treated and untreated Sko007 cells.为了研究白细胞介素 6 (IL 6 )作用相关基因以及一些可能受IL 6调控的基因 ,利用一个简单快速的以PCR为基础的方案 ,检测了IL 6处理和未处理的Sko0 0 7细胞中基因表达的差异 ,克隆并鉴定了差异表达基因的cDNA片段 。
6)differential gene expression差异基因表达
1.To elucidate the differential gene expression during the development of stamens in female flower buds of bitter melon gynoecious line induced with AgNO3, in the present study, it was studied at the levels of morphology and transcription genomics using morphologic observations, cDNA-AFLP, RT-PCR and reverse-Northern hybridization.为了研究AgNO3诱导下纯雌系苦瓜花蕾发育过程中的差异基因表达,本文运用形态学观察、cDNA-AFLP、RT-PCR和反向Northern杂交等技术在形态学和转录组学水平上对花蕾转雄进行了研究。
延伸阅读
表达谱差异分析表达谱差异分析(differential expression profiling)主要包括基因表达谱(gene expression profiling) 和蛋白质表达谱(protein expression profiling) 。大规模表达谱分析已经成为认识疾病分子机制的有利方法,在癌症研究等方面取得了一定的进展。成功的表达谱分析基于实验及其过程分析的有机结合。实验过程从关注的疾病开始,首先收集大量的疾病相关组织样本,样本数量可从10 多个到数百个,但必须足以对每一组织类型及个体差异进行比较分析,而且许多情况下不能仅简单地分为正常和疾病组织。例如,在对糖尿病的研究中,所收集的样本来自健康人、胰岛素耐受和糖尿病病人的不同试验阶段,如胰岛素治疗前后。样品还应包括其他器官的取材,以便进行基因表达的组织分布研究。为了便于对后来的实验数据进行分析管理,需采集并储存所有的组织样本和临床参数。接下来进行组织样本的处理,利用生物芯片(寡核苷酸芯片、cdna 芯片或全基因组芯片) 进行表达谱测定,并进行生物信息学分析。通常,表达谱的分析结果需进一步的实验加以证实。定量rt2pcr 是最灵敏的确证方法,该方法还可以将确证实验的范围扩大到原测组织以外的更广泛的组织和组织类型,揭示基因表达的组织分布情况。确证实验揭示了疾病相关基因。据此,可以进行进一步研究,探索这些基因的功能,开发新的治疗手段。例如,对于正常和疾病组织中表达有显著性变化的基因,可以进行新治疗靶点的鉴定和确定研究,或利用实验和分析工具研究分析其功能;对于疾病组织中活性升高的酶,可以当作前药活化酶进行鉴定研究。典型的表达谱能够显示疾病过程中有大量的已知基因表达的改变,而许多已知基因的代谢通路、表达产物酶学分类和蛋白质功能业已发表,将两者对照分析,可以鉴定出酶活性,选择其中可能成为前药活化酶的部分进行进一步研究;对于疾病特异的蛋白质,可以进行抗原表型分析,决定疫苗的开发策略。寻找差异表达基因的方法除芯片技术外,一些新的检测方法如差异显示pcr ( differential display pcr, dd－pcr) 、消减杂交( suppression subreactive hy bridization , ssh) 等也相继得到结合应用。
