1)non-receptor tyrosine kinase非受体酪氨酸激酶
1.Interaction of non-receptor tyrosine kinase Arg and catalase;非受体酪氨酸激酶ARG与过氧化氢酶相互作用机制的初步研究
2.The c-abl gene is expressed ubiquitously as a non-receptor tyrosine kinase in mammalian and human cells.非受体酪氨酸激酶c-Abl广泛表达于人和哺乳动物等的细胞中并受到严格调控,通过蛋白之间相互作用、与DNA相互作用及其酪氨酸激酶活性在一系列的重要生命活动中发挥调节作用。
英文短句/例句
1.c-Abl Stabilizes Estrogen Receptor by Phosphorylation and Regulates Its Transcription Activity;c-Abl非受体酪氨酸激酶调节ERα转录活性的研究
2.The Study on the Transcripition Activity Modulation of C/EBPβ by c-Abl Non-Receptor Tyrosine Kinase;c-Abl非受体酪氨酸激酶调节C/EBPβ转录活性的研究
3.Functional Interaction between HAX-1 and c-Abl Non-receptor Tyrosine Kinase;HAX-1与c-Abl非受体酪氨酸激酶相互作用及其生物学意义
4.Functional Interaction between c-Abl Non-receptor Tyrosine Kinase and FHL2c-Abl非受体酪氨酸激酶与FHL2相互作用及其生物学意义
5.Expression of receptor tyrosine kinase EphA1 in gastric cancer and its clinicopathological significance受体酪氨酸激酶EphA1 mRNA在胃癌中的表达
6.Expression and Clinical Significance of Receptor Tyrosine Kinase RON in Lung Carcinoma肺癌组织中酪氨酸激酶受体RON的表达及意义
7.Molecular targeted therapies:targeting receptor tyrosine kinases in the treatment of gastric cancer靶向于受体酪氨酸激酶的胃癌分子靶向治疗
8.Advances in the inhibitors of FLT-3 receptor tyrosine kinaseFLT-3受体酪氨酸激酶抑制剂的研究进展
9.Expression of receptor tyrosine kinase EphA7 in gastric carcinoma and its clinical significances受体酪氨酸激酶EphA7基因在胃癌中的表达及意义
10.Effect of Receptor Protein-tyrosine Kinases in Tumor Angiogenesis受体酪氨酸激酶在肿瘤血管新生中的作用
11.Progress in research of multi-targeted inhibitors of receptor tyrosine kinase多靶点受体酪氨酸激酶抑制剂的研究进展
12.Preparation of Monoclonal Antibodies Against RON Receptor Tyrosine Kinase;抗RON受体酪氨酸激酶单克隆抗体的制备和生物学特性研究
13.The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
14.The Effect of Receptor Tyrosine Kinase Inhibitor on Repair Tissue in Chondrocyte and Osteoarthritis Cartilage;受体酪氨酸激酶抑制剂在软骨修复中的作用研究
15.Prevalence and Clinical Significance of Type Ⅲ Receptor Tyrosine Kinases in Acute Leukemia;Ⅲ型受体酪氨酸激酶与急性白血病的关系及临床意义
16.Experimental Studies on Rat Bone Marrow Stromal Cells Modified with Protein-tyrosine Kinase Receptor B Gene;蛋白酪氨酸激酶受体B基因修饰骨髓基质细胞的实验研究
17.The Experimental Study on the Effect of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor on Polycystic Kidney Disease;表皮生长因子受体酪氨酸激酶抑制剂治疗多囊肾病的实验研究
18.Expression and Mutational Analysis of Receptor of Tyrosine Kinase in Neuroendocrine Lung Carcinoma;酪氨酸激酶受体表达、突变与肺神经内分泌癌患者临床预后关系
相关短句/例句
Abl non-receptor tyrosine kinasesAbl非受体酪氨酸激酶
3)c-Abl non-receptor tyrosine kinasec-Abl非受体酪氨酸激酶
4)Receptor tyrosine kinase受体酪氨酸激酶
1.Expression and its clinical significance of receptor tyrosine kinase EphB1 in gastric carcinoma受体酪氨酸激酶EphB1在胃癌中的表达及其临床意义
2.Mer is one member of Axl receptor tyrosine kinase family, and its ligand Gas6 can stimulate activity of Mer receptor tyrosine kinase after binding it, and then activate the downstream signal transduction pathway, Mer participates in cell inflammation, apoptosis, tumorigenesis, thrombosis and hemostasis.Mer是Axl受体酪氨酸激酶家族中的一员,其受体Gas6和Mer结合后可以激活Mer的酪氨酸激酶活性,并激活下游信号传导途径,在细胞炎症、凋亡、血液肿瘤发生发展以及血栓于止血等方面发挥作用。
3.FLT3,a member of receptor tyrosine kinase III family,is primarily expressed by hematopoietic cells and plays a significant role in hematopoiesis and leukemogenesis.FMS-like Tyrosine Kinase 3(FLT3)是一种受体酪氨酸激酶,在造血干细胞、前体B细胞等的增殖、分化以及存活中具有重要作用。
5)receptor tyrosine kinases受体酪氨酸激酶
1.Modulation of potassium channels by receptor tyrosine kinases:recent progress;受体酪氨酸激酶调节钾离子通道功能的研究进展
2.The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases have close connection with the initiation, progression and progn osis of various malignancies.表皮生长因子受体 (EGFR)家族的受体酪氨酸激酶与多种恶性肿瘤的发生、发展及预后等密切相关。
6)RTK受体酪氨酸激酶
1.Receptor tyrosine kinase (RTK) inhibitors targeting VEGF receptor is one of the most promising agents.血管内皮细胞生长因子 (VEGF)是体内活性最强、专属性最高的促血管生成因子 ,故成为寻找血管生成抑制剂的重要靶点 ,其中靶向 VEGF受体酪氨酸激酶的抑制剂令人最为关注。
2.Our study is aimed to investigate whether EphA3,which is a member of RTK family,can play a role in PCa progression and whether it can promote the transition of PCa from androgen dependent stage to androgen independent stage as well as the mechanism of its function.本课题旨在阐明受体酪氨酸激酶家族分子EphA3能否在前列腺癌进展中发挥作用,能否促进前列腺癌从雄激素依赖向雄激素非依赖的转变,并探索其发挥作用的分子机制,为发现新的前列腺癌相关信号转导途径,发现新的药物靶标和诊断治疗方法奠定基础。
延伸阅读
酪氨酸蛋白激酶抑制剂分子式:CAS号:性质:一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化,是许多配体活化的生长因子受体和一些癌基因产物,在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂,也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码,抑制细胞增殖,可望开发为抗肿瘤药物,但对完整细胞没有表现出选择性。