先导物,lead英语短句,例句大全

先导物,lead
1)lead[英][li:d][美][lid]先导物
1.Strategy of molecular drug design:hits,leads and drug candidates;药物分子设计的策略:苗头和先导物的品质决定新药的成败

英文短句/例句

1.Discovery of Lead Compound Liguzinediol and Study of Its Positive Inotropic Effect on MyocardiumLiguzinediol先导物的发现及正性肌力活性研究
2.Natural products are one of the moat important sources of the lead compounds in drug discovery.天然产物是药物先导化合物的重要来源。
3.Natural products provide the most important sources of lead compounds in drug discovery.天然产物是药物发现中先导化合物的重要来源。
4.Anticardiovascular Disease Agent from Insects;从昆虫体内分离抗循环疾病药物的先导化合物
5.Biosynthesis of Mildiomaycin Derivative and Its Analysis Identification;米多霉素类先导化合物的生物合成与分析鉴定
6.Studies on Lead Compounds of Brown Alga Leathesia Nana and Marine Sponge Tedania sp.;小粘膜藻和苔海绵活性先导化合物研究
7.Synthesis and Biological Activities of Pesticide Lead Compound;亚结构连接法合成筛选农药先导化合物
8.Discovering hIL-6 Antagonist from Synthetic Compound Database by Using Structure-Based Virtual Screening;基于结构信息虚拟筛选hIL-6拮抗先导化合物
9.On Consensus Orientation in Publicizing & Reporting Advanced Figures;关于宣传报道先进人物的舆论导向问题
10.Material Flow of Demand Flow Leadership Based on Advanced Manufacture Model;基于先进制造模式的物流需求流动领导
11.Ventilation analysis and pre-control for varied pollutant emission rates污染物散发量变化时的通风解析及先导控制
12.Natural Products--A Source of New Lead Compounds天然产物是农药新型活性结构的重要先导库
13.Research on pilot test of biologic-enzyme enhanced oil recovery in Gangxi oil reservoir of Dagang Oilfield大港油田港西生物酶驱油先导性试验研究
14.Research and synthesis of a key intermediate of HMOA with anti-HIV activity抗艾滋病先导化合物HMOA重要中间体的合成
15.Drug design has been relied on target enzyme which usually is a protein molecule.基于靶标结构的药物设计方法是先导药物设计的重要手段。
16.Synthesis and Bioactivity of Novel 1, 3, 4-oxadiazole Derivatives Derived from Gallic Acid;以没食子酸为先导合成具有生物活性的1，3，4-噁二唑衍生物
17.Novel Antitumor Precursor of Color Derivatives Aiming of DNA: Design, Synthesis and Evaluation Biological Activity;以DNA为靶标的色素衍生抗肿瘤先导化合物的合成和生物活性
18.Studies on Designation and Synthesis of the Leading Compound Desmosdumotin C Derivatives;活性先导化合物毛叶假鹰爪素C衍生物的设计与合成

相关短句/例句

lead compounds先导化合物
1.Recent advances in the study of antifungal lead compounds with new chemical scaffolds;新结构类型抗真菌先导化合物的研究进展
2.Chemical modification of lead compounds by monasacchrides and their derivatives;糖类对先导化合物的化学修饰及其在药学中的应用
3.In order to find screening rules suitable for lead compounds of pesticide,five descriptors:logarithm of partition coefficient of octanol/water(LogP),relative molar weight(MW),number of hydrogen-bond donors(NHD),number of hydrogen-bond acceptors(NHA),polar surface area(PSA)and carcinogenic and mutagenic toxicities of 242 fungicides,512 herbicides and 399 insecticides were calculated and analyzed.为了寻找适合于农药的先导筛选规则,对242个杀菌剂、512个除草剂和399个杀虫剂的5个描述符:疏水常数(LogP)、相对分子质量(MW)、氢键给体数(NHD)、氢键受体数(NHA)、分子极性表面积(PSA)和毒性进行了计算和分析,提出了杀菌剂、除草剂和杀虫剂先导化合物的筛选规则。
3)lead compound先导化合物
1.Design, synthesis and biological activity of the novel lead compound ethyl 2-(2-chloro-4-trifluoromethylphenoxy)-4-trifluoromethyl-thiazole-5-carbonate;新型先导化合物2-(2-氯-4-三氟甲基苯氧基)-4-三氟甲基噻唑-5-甲酸乙酯的设计、合成与生物活性
2.Marine biological toxins——A kind of important lead compounds for new drug research;海洋生物毒素——一类重要的新药研究先导化合物
3.A novel lead compound, 4-[4-(3, 4-dimethoxyphenyl)-2-methyl-thiazole-5-carbonyl] morpholine (5), was designed and synthesized from 3, 4-dimethoxyacetophenone via six steps: esterification, chlormation, ring condensation, and hydrolysis to form the free acid, followed by formation of the acid chloride which, when reacted with morpholine, produces the desired amide (5).以3,4-二甲氧基苯乙酮为原料,经酯化、氯化、环化、水解、酰氯化和胺化六步制得新型先导化合物4-[4-(3,4-二甲氧苯基)-2-甲基噻唑-5-甲酰基]吗啉(5)。
4)leading compounds先导化合物
1.Methodology for quick finding of leading compounds based on botanical metabonomic concept of determination for mixture by 1H-NMR;基于植物代谢组学混合物氢谱测定概念快速发现先导化合物的方法学研究
2.As leading compounds these stilenes were modified by alkylation, glycosylation and association on the basis of the theory of structure modification and the theory of structure-activity relationships.合成了55种化合物,其中有16种结构简单的芪类化合物和20种修饰产物,前者经初步活性检测表明:化合物1、3、4、6具有抑制肿瘤细胞的活性;以它们为先导化合物,根据先导化合物的结构修饰和构效关系理论,进行了以下修饰。
3.Computer-aided drug design(CADD) which playing a hinging role during new drug research and development is a multi-subject crossing subject,especially the discovery and optimization of leading compounds.计算机辅助药物设计(CADD)是多学科交叉的边缘学科,在药物研发过程中起着枢纽作用,特别在先导化合物的发现和优化中发挥重要作用。
5)leading compound先导化合物
1.The work of isolating, purifying and identifying new leading compounds from Rhodomela confervoides and Scylosiphon lomcnkirins w.并对其中生物量较大的松节藻、萱藻进行了先导化合物的分离纯化和结构鉴定，从中分离纯化出色素、甾醇、甘油酯和溴酚类化合物30多个，并运用一维核磁共振(~1HNMR、~(13)CNMR、DEPT)、二维核磁共振(~1H-~1Hcosy、HMBC、HMQC)、红外光谱(IR)、质谱(EI/MS、FAB/MS)等现代波谱分析技术分析鉴定了化合物15个，其中15个为新化合物，1个为首次从自然界中分离得到。
6)repair of lead compound先导物修饰