1)dual siRNA双siRNA
2)small interfering RNAsiRNA
1.Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.Construction of small interfering RNA targeting mouse vascular endothelial growth factor receptor-2:its serum stability and gene silencing efficiency in vitro靶向VEGFR2基因的siRNA分子血清稳定性及其基因沉默效应
英文短句/例句
1.Plasmid-based siRNA Silencing of GATA-1 Gene Expression;GATA1 siRNA的制备及其鉴定
2.Antilymphangiogenic Therapy of Colorectal Cancer Xenograft Model Blockade by SiRNA Compared with Adenovirus-mediated VEGF-C siRNAsiRNA和携带siRNA重组腺病毒抑制结肠癌移植瘤淋巴管生成的比较
3.Experimental Study of OPN Gene Silencing Mediated by siRNA in Laryngeal Squamous Cell Carcinoma;siRNA沉默OPN基因治疗喉鳞癌的实验研究
4.The Experimental Study on the Treatment of Cervical Cancer with the HPV16-E6-Targeted siRNA;靶向HPV16 E6的siRNA治疗宫颈癌的实验研究
5.Effect of Small Interfering RNA Targeting Polo-like Kinase 1 on Apoptosis in Hepatocellular Cell;靶向Plk1的siRNA对肝癌细胞凋亡的影响
6.The Reversal Effect on Multidrug Resistance Gene 1 Mediated Multidrug Resistance in Human Gastric Cancer Cells by Small Interfering RNA;siRNA逆转人胃癌细胞mdr1介导的多药耐药
7.Studies on siRNA Interfering TMV Infection and Its Molecular Mechanism;siRNA干扰TMV侵染及其分子机理的研究
8.Experimental Research on Breast Cancer Therapy Using siRNA Targeting HER-2;靶向HER-2的siRNA治疗乳腺癌的实验研究
9.The Interference of Small Interfere RNA Targeting STAT3 in Colorectal Cancer Cell;STAT3-siRNA对结直肠癌细胞的干涉作用
10.Silencing Effect Study of Akt2-siRNA Aim at Lung Cancer Cell NCI-H446;Akt2-siRNA对肺癌细胞NCI-H446沉默作用的研究
11.The Preliminary Study of siRNA Targeting EGFR;以EGFR为靶点siRNA的初步研究
12.The Inhibitory Effects of the siRNA Against c-myc on HL-60 Cells;特异性c-myc siRNA对HL-60细胞的抑制作用
13.Inhibition of SARS-CoV Replication by Small Interfering RNAs;siRNA对SARS冠状病毒复制的抑制作用研究
14.Effect of siRNA Targeting the Subunit of Telomerase on Hepatocellular Carcinoma;端粒酶亚单位的siRNA对肝癌的作用
15.Research on siRNA Sequence Design in RNAi Technology;RNAi技术中的siRNA序列设计方法研究
16.Study on Molecular Features of Small Interference RNA;RNA干涉效应分子siRNA分子特性的研究
17.Effects of HPV18-E6 Gene siRNA on Cultured Hep-2 Cells;HPV18-E6基因siRNA对喉癌细胞的生长影响
18.siRNA Targeting S Gene Inhibits Hepatitis B Virus Expression and Replication in HepG2.2.15 Cells;siRNA抑制HBV S基因在HepG2215细胞中的表达
相关短句/例句
small interfering RNAsiRNA
1.Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.Construction of small interfering RNA targeting mouse vascular endothelial growth factor receptor-2:its serum stability and gene silencing efficiency in vitro靶向VEGFR2基因的siRNA分子血清稳定性及其基因沉默效应
3)small interference RNAsiRNA
1.Objective To evaluate the effectiveness of small interference RNA (siRNA) on inhibiting bcl-2 gene expression.目的研究小干扰RNA(siRNA)对bcl-2基因表达的抑制作用。
2.To study the regulation mechanism of HIF-1α in proliferation and differentiation of stem cells, two small interference RNA expression vectors of HIF-1α were constructed, and transfected into the fetal liver stromal cell lines (FLSCs) stably by lentiviral system.为了研究低氧诱导因子(hypoxia inducible factor-1alpha,HIF-1α)在干细胞增殖分化过程中的作用机制,构建了2个HIF-1α慢病毒siRNA干涉载体,并转染人胎儿肝脏基质细胞(fetal liver stromal cell,FLSC)。
3.Objective To study the effect of small interference RNA on E6, E7mRNA of human papillomavirus type-18(HPV18) in cervical cancer cells and its therapy action to cervical cancer.目的 探讨siRNA(short interfering RNAs)对宫颈癌细胞人乳头状瘤病毒(HPV)18型E6、E7 mRNA表达的干扰作用。
4)RNAisiRNA
1.Conclusions:RNAi mediated by chemically modified siRNA efficiently knocked-down VEGFR-1 gene expression and inhibited cellular proliferation.目的:体外水平探讨利用化学修饰的小干扰RNA(small interfering RNA,siRNA)敲减VEGFR-1基因治疗乳腺癌的可行性和特异性。
2.Knockdown fusion gene SYT-SSX expression by RNAi induces apoptosis in synovial sarcoma cells line HS-SY-Ⅱ;目的研究siRNA(smallinterferingRNA)对滑膜肉瘤细胞系HS-SY-II中融合基因SYT-SSX表达的抑制作用,为RNAi技术在肿瘤生物治疗中的应用提供实验基础。
5)small interfering RNA targeting Rac1Rac1-siRNA
1.Experimental study of small interfering RNA targeting Rac1 inhibits NF-κB expression in retina of rat model;Rac1-siRNA抑制大鼠视网膜NF-κB表达的实验研究
6)siRNA interferencesiRNA干扰
延伸阅读
Sirna
sirna
small interfering rna (sirna)：是一种小rna分子（~21-25核苷酸），由dicer（rnaase ⅲ家族中对双链rna具有特异性的酶）加工而成。sirna是sirisc的主要成员，激发与之互补的目标mrna的沉默。
