1)telomerase RNA端粒酶RNA
1.Expression of human telomerase RNA in ameloblastoma;人端粒酶RNA在成釉细胞瘤中的表达
2.Aim:To explore the effects of human telomerase RNA(hTR) antisense oligodeoxynucleotide (ASODN) on the telomerase activity, cell apoptosis,and the expression of apoptosis inducing factor (AIF) of EC9706 cells.目的:探讨封闭端粒酶RNA功能区的反义寡核苷酸(hTR ASODN)对食管癌EC9706细胞端粒酶活性、细胞凋亡及凋亡诱导因子(AIF)表达的影响。
3.Objective To explore the expression of human telomerase RNA (hTR) component and telomerase reverse transcriptase (hTERT) mRNA in lesions of psoriasis vulgaris and their relationships with keratinocytes proliferation.目的探讨端粒酶RNA(hTR)和反转录酶(hTERT)在银屑病皮损中的表达情况以及它们与角质形成细胞增殖关系。
英文短句/例句
1.Telomerase RNA Gene (TERC) and Recent Studies on Cervical Cancer端粒酶RNA基因(TERC)与宫颈癌研究进展
2.Construction of a bait plasmid containing human telomerase RNA mutant in yeast three-hybrid system人端粒酶RNA突变体酵母三杂交诱饵质粒的构建
3.Construction of Screening Model for Telomerase Inhibitors Contained Human Telomerase RNA Mutant含人端粒酶RNA突变体的端粒酶抑制剂筛选模型的构建
4.Study on the Effect of shRNA of chTR on Telomerase Activity of Cell端粒酶RNA亚基的shRNA对细胞端粒酶活性影响的研究
5.Advance of correlation between human telomerase RNA gene and tumor人端粒酶RNA基因与肿瘤的相关研究进展
6.Inhibition of Mutant Template Human Telomerase RNA on HeLa Cell Growth端粒酶RNA亚基模板突变抑制HeLa肿瘤细胞的生长
7.Inhibitory Effect of Antisense Human Telomerase RNA(hTR) Gene Mediated by Retroviral Vector on the Hepatocellular Carcinoma Cells.;逆转录病毒介导反义端粒酶RNA基因对肝癌细胞的影响
8.Effects of the Retrovirus Vector Containing Retro-hTR Gene on Growth of SGC7901 Cell Line;逆转录病毒介导的反义人端粒酶RNA基因对胃癌细胞生长的影响
9.Detection of Genomic Amplification of Human Telomerase Gene (hTERC) in Cytologic Specimens in the Screening of Cervical Lesions人端粒酶RNA基因(hTERC)检测在子宫颈病变筛查中的应用
10.Research on the Retrovirus-mediated Antisense Human Telomerase RNA (hTR) Gene Induces the Apoptosis of Hepatocellular Carcinoma逆转录病毒介导的反义端粒酶RNA基因诱导肝癌凋亡机制的研究
11.Construction of recombinant retroviral vector encoding antisense human telomerase RNA component编码反义人端粒酶RNA组分重组逆转录病毒载体的构建
12.Inhibitory effect of antisense human telomerase RNA on implanted hepatocellular carcinoma in nude mice反义端粒酶RNA基因对裸鼠肝癌移植瘤的抑制作用
13.Effective Inhibition of Telomerase Activity in Breast Cancer Cell T47D by siRNA;小干扰RNA抑制乳腺癌T47D细胞端粒酶活性的研究
14.Inhibitions of Telomerase Activity on K562 Cell Line by Plasmid-vector Directing RNAi Against hTERT;质粒介导RNA干扰靶向hTERT抑制K562细胞端粒酶活性的研究
15.Establishment of RNA Interference Targeting Against Human Telomerase Reverse Transcritase (hTERT) and Research for It's Biological Effects;靶向人端粒酶逆转录酶(hTERT)RNA干扰的建立及其生物学效应的研究
16.Inhibitory Effects of Oncolytic Adenovirus with hTERT Small Interference RNA on Proliferation of Human Cervical Cancer HeLa Cells溶瘤腺病毒介导RNA干扰人端粒酶逆转录酶抑制HeLa细胞生长
17.Effect of hTERT RNA interference on biological characteristics of colon carcinoma人端粒酶逆转录酶RNA干扰对结肠癌细胞生物学行为的影响
18.Telomerase Activity in Gastric Cancer and Effect of Telomerase Antisense RNA on the Malignant Phenotype of Gastric Cancer Cell Line SGC7901;端粒酶在人胃癌中的表达及端粒酶反义RNA对SGC7901胃癌细胞恶性表型的影响
相关短句/例句
Human telomerase RNA端粒酶RNA
1.This study was to evaluate the effects of small interfering RNA(siRNA) against either the template RNA(human telomerase RNA,hTR) or its catalytic subunit(human telomerase reverse transcriptase,hTERT) of telomerase gene on the telomerase activity and the growth inhibition of human transitional cell carcinoma of bladder cell line BIU-87.目的探讨针对人端粒酶RNA(hTR)及其催化亚基(hTERT)的小干扰RNA(siRNA)对膀胱移行细胞癌细胞株BIU-87端粒酶活性及其增殖的影响。
3)Human Telomerase RNA人端粒酶RNA
1.Construction of a Highly Expressed New Type Retrovirus Expressing Human Telomerase RNA and its Impact on Hepatocyte Proliferation;高效表达人端粒酶RNA逆转录病毒的构建及其对肝细胞增殖的影响
2.Construction of a bait plasmid containing human telomerase RNA mutant in yeast three-hybrid system人端粒酶RNA突变体酵母三杂交诱饵质粒的构建
4)nasopharyngeal epithelia端粒酶和端粒酶RNA
5)Human telomeric RNA人类端粒酶RNA
6)human telomerase RNA(hTR)人端粒酶RNA(hTR)
延伸阅读
端粒酶分子式:CAS号:性质:一种以逆转录的方式合成真核细胞中线性染色体端粒DNA的特殊酶。该酶的辅基为一特定的RNA,端粒DNA的合成必须依赖酶分子中的辅基RNA为模板,通过逆转录而完成,其自身携带RNA作为产物的模板是区别于一般由纯蛋白组成的逆转录DNA聚合酶的主要特征。在逆转录时需要一个DNA引物,以便从5′→3′方向添加端粒的重复序列。底物是脱氧核苷三磷酸(dNTPs)。如在四膜虫(tetraphymena)中,四膜虫端粒酶催化反应式如下:染色体-GGGGTTGGGGTT(DNA引物)+4ndGTP(dNTPs)+2nTTP(dNTPs)→染色体-GGGGTTGGGGTT(GGGGTT)n(四膜虫端粒DNA)+6n焦磷酸端粒酶的活性在胚系细胞、癌化细胞中活跃;在体细胞,尤其经多次分裂后的体细胞,其活性降低。该酶的活性也可能是多细胞器官限制其细胞增殖的一种机制之一。