1)Histone deacetylase inhibitor组蛋白去乙酰化酶抑制剂
1.Inhibitory effect of histone deacetylase inhibitor FK228 on LNCaP prostate cancer cells;组蛋白去乙酰化酶抑制剂FK228对前列腺癌LNCaP细胞的抑制作用
2.Advances in the anticancer effect of histone deacetylase inhibitor组蛋白去乙酰化酶抑制剂抗肿瘤的研究进展
3.The article briefly notices the mechanisms of histone acetylation and deacetylation,and reviews the impact of histone acetylation on genes and proteins associated with different signal transduction pathways,the acetylation status of malignant tumors of head and neck and the inhibiting effect of histone deacetylase inhibitors on tumor cells of head and neck malignancy.本文简介了组蛋白乙酰化和去乙酰化的机制,并就组蛋白乙酰化对头颈部恶性肿瘤细胞中与不同信号转导通路有关的基因、蛋白表达的影响,以及头颈部恶性肿瘤的乙酰化状况和组蛋白去乙酰化酶抑制剂对头颈部恶性肿瘤细胞的生长抑制作用作一综述。
英文短句/例句
1.Histone deacetylases inhibitors anticancer drug:Vorinostat组蛋白去乙酰化酶抑制剂类抗癌药Vorinostat
2.The Design and Synthesis of Cyclic Tetrapeptide Histone Deacetylase Inhibitors;环肽类组蛋白去乙酰化酶抑制剂的设计与合成
3.Advances in the anticancer effect of histone deacetylase inhibitor组蛋白去乙酰化酶抑制剂抗肿瘤的研究进展
4.Synergistic Effect of Histone Deacetylase Inhibitor SBHA with Proteasome Inhibitors Bortezomib or MG-132 on Breast Cancer Cells;组蛋白去乙酰化酶抑制剂与蛋白酶体抑制剂协同抑制乳腺癌细胞及分子机制研究
5.Inhibition Effect of Histone Deacetylase Inhibitor FK228 on Prostate Cancer Cells;组蛋白去乙酰化酶抑制剂FK228对前列腺癌细胞的抑制作用
6.Experimental Study on the Synergistic Inhibition of Hepatoma Cell Lines with Histone Deacetylase Inhibitor and 5-FU;组蛋白去乙酰化酶抑制剂与5-FU协同抑制肝癌细胞的实验研究
7.Immunosuppressive function of histone deacetylases inhibitors:recent progress组蛋白去乙酰化酶抑制剂的免疫抑制功能研究进展
8.Anticancer Activities of Histone Deacetylase and DNA Methyltransferase Inhibitors on Pancreatic Cancer;DNA甲基化酶和组蛋白去乙酰化酶抑制剂治疗胰腺癌的实验研究
9.The Establishment of Screening Models for Histone Deacetylase Inhibitors and Their Application in Screening of the Chinese Traditional Medicine Effective Components;组蛋白去乙酰化酶抑制剂筛选模型的建立及中药有效组分的筛选
10.Molecular Mechanisms of Histone Deacetylase Inhibitors Induced Mitotic Catastrophe in Tumor Cells;组蛋白去乙酰化酶抑制剂诱导细胞有丝分裂灾变的分子机制探讨
11.Histone Deacetylase Inhibitor and Methylase Inhibitor Repress Synergistically Differentiation of HSC;组蛋白去乙酰化酶抑制剂及甲基转移酶抑制剂协同抑制造血干细胞分化
12.Histone Deacetylase Inhibitors of Polyoxometalates: Screening and Anti-Tumor Activity;多酸类组蛋白去乙酰化酶抑制剂的筛选及抗肿瘤活性研究
13.The Screening and Primary Functional Study of Histone Deacetylase Inhibitors from Polyoxometallates;多酸类组蛋白去乙酰化酶抑制剂的筛选及初步功能研究
14.Studies on Design、Synthesis and Activity of Hydroxamate Acids Derivatives as Histone Deacetylases Inhibitors;异羟肟酸类组蛋白去乙酰化酶抑制剂的设计合成与活性研究
15.The Effect of HDAC Inhibitor on Breast Cancer and ERα Expression;探讨组蛋白去乙酰化酶抑制剂对乳腺癌及ERα表达的影响
16.The Effect of Histone De-acetylase Inhibitor on RECK Gene Expression in Breast Cancer;组蛋白去乙酰化酶抑制剂对乳腺癌中RECK基因的表达影响研究
17.Study of Histone Deacetylase Inhibitor on the Target Therapy of Ovarian Cancer组蛋白去乙酰化酶抑制剂在卵巢癌靶向治疗中的作用研究
18.Effects of histone deacetylase inhibitor MS-275 in vitro on proliferation of U266 cell line组蛋白去乙酰化酶抑制剂MS-275对U266细胞增殖的影响
相关短句/例句
histone deacetylase inhibitors组蛋白去乙酰化酶抑制剂
1.Mechanism of histone deacetylase inhibitors for treatment of hematological cancer and their clinical research;组蛋白去乙酰化酶抑制剂治疗血液系统肿瘤的作用机制及临床应用
2.Molecular mechanism of p21~(WAF1/CIP1) expression induced by histone deacetylase inhibitors in HeLa cell line;组蛋白去乙酰化酶抑制剂诱导H eLa细胞p21~(WAF1/CIP1)表达的分子机制研究
3.Mechanism of regulating multidrug resistances by histone deacetylase inhibitors in tumor cells;组蛋白去乙酰化酶抑制剂调节肿瘤细胞多药耐药性的机制
3)HDACi组蛋白去乙酰化酶抑制剂
1., Histone deacetylase inhibitors (HDACI) was proven to inhibit gliomas cell growth and proliferation via various mechnisms,including cell cycle arrest, induction of cell differentiation and apoptosis, as well as inhibition of angiogenesis.组蛋白去乙酰化酶抑制剂作为一种新型的化疗药物为胶质瘤的治疗提供了新的方向。
4)histone deacetylase inhibitors组蛋白去乙酰酶抑制剂
1.Progress in the research of histone deacetylase inhibitors;组蛋白去乙酰酶抑制剂的研究进展
5)histone deacetylase inhibitor(HDACI)组蛋白去乙酰化酶抑制剂(HDACI)
6)Inhibitor of HDACs吲哚酰胺异羟肟酸类组蛋白去乙酰化酶抑制剂
延伸阅读
蛋白酶抑制剂分子式：CAS号：性质：从广义上指与蛋白酶分子活性中心上的一些基团结合，使蛋白酶活力下降，甚至消失，但不使酶蛋白变性的物质。从放线菌发酵液中分离到亮肽素、抗痛素、糜蛋白酶抑素、抑弹性蛋白酶醛、抑胃蛋白酶素、磷酰胺素等，能分别抑制胰蛋白酶、木瓜蛋白酶、糜蛋白酶、弹性蛋白酶、胃蛋白酶、金属蛋白酶等各种蛋白酶。都属于蛋白酶抑制剂。能减慢或完全停止某一酶促反应直接或间接地影响酶活性中心的作用。通常抑制作用可分为可逆性和不可逆性两大类。
