1)loss of heterozygosity杂合性缺失
1.Identification of some macrosatillite sites of chromosome 19 in primary gastric carcinoma with loss of heterozygosity;19号染色体微卫星杂合性缺失与原发性胃癌的临床关系
2.Analysis of loss of heterozygosity in tk gene of L5178Y mouse lymphoma cells induced by colchicine and vincristine;秋水仙碱和长春新碱诱导L5178Y小鼠淋巴瘤细胞tk基因杂合性缺失分析
3.Study of loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma;胃癌FHIT基因杂合性缺失及微卫星不稳定性的研究
英文短句/例句
1.Experimental Study of Loss of Heterozygosity and Imprinting of CDKN1C on Laryngeal Squamous Cell Carcinoma;喉鳞状细胞癌中CDKN1C基因杂合性缺失和印记缺失的实验研究
2.The Relationship between the Loss of Heterozygosity and Loss of Expression of p57~(kip2) mRNA人肝癌p57~(kip2)基因表达缺失与杂合性缺失的关系研究
3.Loss of Heterozygosity Analysis at 6q16-q23 in Pathogenesis of Non-Hodgkin Lymphomas;6q16-q23杂合性缺失与NHL发病相关性的初步研究
4.Investigation of the Loss of the Heterozygosity to nm23-H_1 Gene and Its Association with the Biocharicteristics of Lung Cancer;nm23-H_1基因杂合性缺失与肺癌生物学特性
5.Study on the correlation between the loss of microsatellite heterozygosity and thyroid carcinoma微卫星杂合性缺失与甲状腺癌相关性研究
6.Detection and Significance of Loss of Heterozygosity on 8p22 in Chronic Myeloid Leukemia慢性粒细胞白血病8p22杂合性缺失的检测及意义
7.Loss of Heterozygosity and Protein Expression of p73 Gene in Breast Cancer;乳腺癌p73基因杂合性缺失及其蛋白表达的研究
8.Loss of Heterozygosity of p16 Gene and Expression of hMSH2 mRNA in Gastric Cancer;胃癌组织p16基因杂合性缺失与hMSH2 mRNA的表达
9.Loss of Hetrozygosity in Esophageal Squamous Cell Carcinoma and Precursor Lesion;食管癌及癌前病变基因杂合性缺失的研究
10.Study of Loss of Heterozygosity and Microsatellite Instability on Chromosome 7 in Leukemia;急性白血病的7号染色体杂合性缺失和微卫星不稳定性研究
11.The Relationship between Loss of Heterozygosity of FHIT Gene and Microsatellite Instability in Sporadic Colorectal Cancer散发性结直肠癌FHIT基因杂合性缺失与微卫星不稳定性的关系
12.Research of Loss of Heterozygaity on Chromosome 3P in Non-small Cell Lung Cancer;非小细胞肺癌3P基因多区域杂合性缺失联合检测的研究
13.Expression, Mutation and LOH of Gene ING1 in Sporadic Colorectal Carcinoma;散发性结直肠癌中ING1基因的表达、突变及杂合性缺失研究
14.Loss of Heterozygosity and Microsatellite Instability on Chromosome 3p14 in Cervical Carcinoma;宫颈癌染色体3p14杂合性缺失和微卫星不稳定性研究
15.Study of Microsatellite Instability and Loss of Heterozygosity on Chromosome 8 in Leukemia;白血病患者8号染色体微卫星不稳定性和杂合性缺失的研究
16.The Investigation of Microsatellite Instability and Loss of Heterozygosity in Laryngeal Squamous Cell Carcinomas;喉鳞状细胞癌中微卫星不稳定性及杂合性缺失的研究
17.Analysis of Loss of Heterozygosity and Microsatellite Instability of 3, 4 Chromosome in Human Squamous Carcinoma in Cervix宫颈鳞癌3、4号染色体杂合性缺失与微卫星不稳定性分析
18.Analysis of loss of heterozygosity and microsatellite instability of chromosome in human cervical carcinoma宫颈癌染色体杂合性缺失和微卫星不稳定性分析
相关短句/例句
LOH杂合性缺失
1.Study on 10q23 LOH and Both Mutation and Expression of PTEN Gene of the Oesophageal Squamous Cell Carcinomas in Chinese Population;中国人食管癌10q23杂合性缺失和PTEN基因突变及表达研究
2.Methods PCR-denaturing polyacrylamide gel electrophoresis-silver staining method was used to detect LOH of three mic- rusatellite locus located in the WWOX gene site of 31 breast cancer tissues.目的检测乳腺癌组织中WWOX基因的杂合性缺失(LOH)状况及WWOX蛋白的表达状况,并探讨其与乳腺癌临床病理参数之间的关系。
3.Objective:To detect the loss of heterozygosity(LOH) of ING1 gene microsatellite and the expression of p33ING1b protein in lung carcinoma and to investigate their association with the carcinogenesis of lung cancer.目的:检测肺癌中抑癌基因ING1微卫星杂合性缺失(LOH)及其主要蛋白产物p33ING1b的表达情况,以探讨ING1基因改变与肺癌发生发展的关系。
3)LOH杂合性缺失(LOH)
1.Studies show that loss of heterozygosity (LOH) on multiple genetic LOH in clear cell renal carcinoma in 10 genetic locus and to find clues for tumor suppressor genes associated with cc-RCC.本研究检测肾透明细胞癌等位基因杂合性缺失(LOH)情况,为寻找与肾透明细胞癌相关的抑癌基因提供线索。
2.Objective:To compare the LOH rate of allelomorphic gene on chromosome 9 at the identical district and site between esophageal squamous carcinoma and cervical squamous carcinoma to explore the related anti-oncogene in common.目的:比较食管和宫颈鳞状细胞癌组织中9号染色体相同区域七个微卫星位点的等位基因杂合性缺失(LOH)率,探寻与两种鳞癌发生、发展共同相关的抑癌基因。
4)Loss of heterozygosity analysis杂合性缺失分析
5)1p loss of heterozygosity1p杂合性缺失
1.Objective To set up the clinical examination method for 1p loss of heterozygosity(LOH).目的建立临床检测少突胶质细胞瘤1p杂合性缺失的手段。
6)loss of heterozygosity杂合缺失
1.Loss of heterozygosity of chromosome 22 in sporadic colorectal carcinoma;散发性结直肠癌22号染色体等位基因杂合缺失
2.Methods: Mutation in exon 3 of β-catenin gene and mutation cluster region of APC gene, loss of heterozygosity and methylation status of promoter 1A of APC gene in breast cancer and normal tissue around tumor were detected by polymerase chain reaction-single strand conformation polymorphism, microsatellite analysis and methylation specific PCR.方法:应用PCR-SSCP、微卫星标记、甲基化特异性PCR方法检测乳腺癌和癌旁正常乳腺组织中β-catenin基因外显子3和APC基因突变密集区突变、APC基因杂合缺失(LOH)和启动子1A区甲基化状态,用RT-PCR检测APC基因mRNA表达;并用免疫组织化学法检测APC和β-catenin蛋白表达。
3.Objective Loss of heterozygosity (LOH) of tumor suppressor gene(TSG) is believed to play a key role in carcinogenesis of colorectal cancer (CRC).目的抑癌基因的杂合缺失(LOH)被认为是结直肠癌形成的通路之一,本实验拟通过对染色体10q23~24区的LOH分析,发现高频杂合缺失区域并筛查与结直肠癌相关的抑癌基因。
延伸阅读
中枢性感觉缺失中枢性感觉缺失central anesthesia 脊髓或脑病变引起的感觉障碍。可分为传导束型(脊髓脑干损伤伤及感觉传导束)、丘脑型(丘脑痛)、内囊型(三偏症)和皮质型(单肢麻木)等不同类型。
