哺乳动物雷帕霉素靶蛋白,mammalian target of rapamycin
1)mammalian target of rapamycin哺乳动物雷帕霉素靶蛋白
1.Mammalian target of rapamycin (mTOR) is a key downstream molecule of PI3K/Akt pathway.哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin,mTOR)是PI3K/Akt通路的下游分子,可接受生长因子、营养、能量等多种信号,是细胞生长和增殖的关键调节分子。
2.Objective:To investigate the effect of the mammalian target of rapamycin(mTOR)inhibitor CCI-779 on the chemosensitivity of androgen-independent prostate cancer cell line PC-3.目的:研究哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂CCI-779对激素非依赖型前列腺癌PC-3细胞株化疗敏感性的影响。
3.Structure and function of mammalian target of rapamycin;哺乳动物雷帕霉素靶蛋白(mTOR)参与细胞内一系列生理病理过程,其存在形式主要有两种:mTOR-Raptor复合物和mTOR-R ictor复合物。
英文短句/例句

1.Expression of phosphorylated mammalian target of rapamycin in colorectal cancer and its significance人大肠癌组织中磷酸化哺乳动物雷帕霉素靶蛋白的表达及意义
2.Expression and Clinical Significance of p-mTOR in Gastric Cancer磷酸化的哺乳动物雷帕霉素靶蛋白在胃癌组织中的表达
3.The mTOR Inhibitor Enhances Chemosensitivity of Androgen-Independent Prostate Cancer Cell Line哺乳动物雷帕霉素靶蛋白抑制剂对前列腺癌激素非依赖型细胞株化疗敏感性的影响
4.The Expression and Effect of mTOR During Mouse Oocyte Maturation哺乳动物雷帕霉素靶蛋白(mTOR)在小鼠卵母细胞成熟过程中的表达及作用
5.Mammalian target of rapamycin inhibitors in the treatment of malignancy after organ transplantation雷帕霉素靶蛋白抑制剂在移植后新发肿瘤中的应用
6.Target of Rapamycin Inhibitors (Sirolimus and Everolimus) Protocol Versus Cyclosporine Protocol for Initial Immunosuppression of Kidney Transplatation Recipients: A Meta-analysis of Randomized Trials肾移植后免疫抑制治疗雷帕霉素靶蛋白抑制剂方案和环孢霉素方案的荟萃分析
7.YPK1 overexpression resulted salt stress hypersensitivity in Saccharomyces cerevisiae is dependent on TOR1过量表达蛋白激酶YPK1使酵母细胞对高盐胁迫的高度敏感依赖于雷帕霉素靶蛋白
8.The albumin in eggs of birds and the cadmium albumen in milks of mammals both supply nutriments for growth.鸟蛋的白蛋白及哺乳动物奶汁中的镉蛋白也都提供生长发育用的营养素。
9.Proteome Analysis of Mammal Plasma Membrane and Breast Carcinomatous Proteome;哺乳动物细胞质膜及乳腺癌变蛋白质组研究
10.Purification of a 25kD Protein from Rapamycin Producing Strain Streptomyces Hygroscopicus ATCC 367817;雷帕霉素产生菌吸水链霉菌ATCC367817菌体25kD蛋白质的纯化 
11.Mechanical and Tribological Behaviours of Several Mammal Keratin Materials;哺乳动物角蛋白材料力学及摩擦学行为研究
12.Studies on Expression of Green Fluorescent Protein in Mammalian Cells;绿色荧光蛋白在哺乳动物细胞中表达的研究
13.Evolution of KRAB Domains in Mammalian Zinc Finger Gene Family哺乳动物锌指蛋白家族中KRAB功能域的进化
14.Proteins and Signal Transductions Related to Spermatozoa Acrosome Reaction in Mammalian哺乳动物精子顶体反应相关的蛋白及信号传导
15.The Animal and Clinical Studies about Rapamycin Eluting Stent;雷帕霉素洗脱支架应用的动物试验和临床研究
16.Prokaryotic Expression of Mammalian Prion and Dopple and Preparation of Monoclonal Antibody Against Bovine Prion;哺乳动物朊蛋白与叠朊的原核表达及牛朊蛋白单抗制备
17.Molecular Evolution of Type Ⅰ Hair Keratin and IRS Keratin Genes of Mammalian哺乳动物Ⅰ型毛角蛋白及IRS角蛋白基因的分子进化
18.In Vitro Study of Effects and Mechanisms of mTOR Inhibitor Rapamycin on Human T-cell Acute Lymphoblastic Leukemia CellsmTOR靶向抑制剂雷帕霉素对人急性T淋巴细胞白血病细胞的作用及机理研究
相关短句/例句

mTOR哺乳动物雷帕霉素靶蛋白
1.To explore the expression rule of mammalian target of rapamycin (mTOR) gene in endometria of early pregnant mouse, real-time fluorescence quantitative PCR (RT FQ-PCR), in situ hybridization, immunohistochemistry and Western blotting were used to detect the mTOR mRNA and protein in the mouse endometria from unpregnant, pseudopregnant and pregnant d3, d4, d5, d6 and d7.利用实时荧光定量PCR、原位杂交法、免疫组化(SP法)和Western印迹法分别检测未孕、假孕及孕d3、d4、d5、d6、d7小鼠子宫内膜哺乳动物雷帕霉素靶蛋白(mammaliantargetofrapamycin,mTOR)mRNA和蛋白质的表达,研究mTOR基因在早孕小鼠子宫内膜的表达规律。
2.Objective To explore inhibitory effect of RNA interference with eukaryotic expression plasmid containing shRNA on expression of mTOR gene in human colon cell line LoVo.目的探讨shRNA真核表达质粒介导的RNA干扰技术对人结肠癌LoVo细胞哺乳动物雷帕霉素靶蛋白(mTOR)基因表达的抑制作用。
3.The proliferation of the cells was detected by MTT assay;the apoptosis rate and cell cycle were determined by flow cytometry(FCM);apoptosis of cells was observed by inverted microscopy;the cylin D1,CXCR4 and mTOR mRNA expressions were detected by RT-PCR or FQ-PCR after treating RPMI8226 cells with different concentrations of rapamycin.不同浓度雷帕霉素作用于RPMI8226细胞不同时间,应用MTT检测细胞的增殖,流式细胞术检测细胞凋亡及细胞周期,半定量PCR检测雷帕霉素干预RPMI8226后细胞周期蛋白D1(cyclinD1)、CXCR4mRNA表达,荧光定量PCR检测哺乳动物雷帕霉素靶蛋白(mTOR)mRNA表达的影响。
3)mTOR哺乳动物雷帕霉素靶体蛋白
4)mammalian target of Rapamycin(mTOR)哺乳动物雷帕霉素靶蛋白(mTOR)
1.Those mammalian target of rapamycin(mTOR)inhibitors such as sirolimus have both immunosuppressive effects on the grafts and targeted anti-tumor effects on the malignancies.以西罗莫司为代表的哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂除了具有强有力的免疫抑制作用外,其对恶性肿瘤的靶向治疗作用近年逐步得到确认,并在临床得到推广。
5)p-Mammalian target of rapamycin磷酸化的哺乳动物雷帕霉素靶蛋白
6)phosphorylated mammalian target of rapamycin磷酸化哺乳动物雷帕霉素靶蛋白
延伸阅读

帕特雷帕特雷(patra)位于伯罗奔尼撒半岛西北部,背依帕纳哈克斯山,西临帕特雷海湾,是希腊西部通往意大利和伊奥尼亚诸岛的重要的港口城市,人口约50万,是希腊第三大城市。帕特雷作为一个城邦形成于公元前6世纪,伯罗奔尼撒战争期间与雅典等城邦结盟。公元前146年被罗马人征服,公元807年又遭斯拉夫人的入侵。而后,一直被法兰克人、威尼斯人和土耳其人占领。1821年希腊独立战争期间,帕特雷是第一个举行反对土耳其人统治的城市。帕特雷还是西部希腊的工商业中心,19世纪末和20世纪初达到鼎盛,20世纪70年代后希腊新兴工业在雅典和萨洛尼卡发展,这里才逐步衰落。主要工业有大理石、酿酒和农产品加工等。帕特雷的主要旅游景点有:帕特雷城堡:位于距离海岸线800米的小山上,建于公元551年。有保存比较完好的墙体和城门及垛楼等。站在城堡上,可以俯看全城景色。古罗马剧场:建于公元170年,现在基本保持完整,有2300个座位,夏季仍然举行露天音乐会。考古博物馆:是希腊最有价值的考古博物馆之一,保存有古希腊城邦时期、罗马和拜占廷时期的许多文物,其中以罗马时期的马赛克拼装画最为著名。