1)chronic myeloid leukemia慢性髓性白血病
1.In order to investigate the features of M bcr/abl and m bcr/abl fusion transcripts in patients with chronic myeloid leukemia (CML) after allogeneic stem cell transplantation (SCT), M bcr/abl and m bcr/abl fusion transcripts were sequentially detected by RT PCR technique in 72 CML patients after SCT.为研究慢性髓性白血病 (CML)异基因造血干细胞移植 (SCT)后M bcr/abl及m bcr/abl融合转录子表达特征 ,采用逆转录 聚合酶链反应 (RT PCR)技术测定 72例CML患者SCT后不同时间骨髓M bcr/abl及m bcr/abl融合转录子的表达。
2.The crucial genetic event in Chronic myeloid leukemia is the generation of a t (9;22)(q34;qll) reciprocal chromosomal translocation in a hematopoietic stem cell.慢性髓性白血病(Chronic myeloid leukemia, CML)是一种起源于多能干细胞的恶性增生性疾病,其最重要的细胞遗传学特征是存在特异性的Ph染色体,第9号染色体上的原癌基因c-ab1易位到第22号染色体的断点集中区(bcr)形成bcr-ab1融合基因,编码bcr-ab1融合蛋白(p210~(bcr-ab1))。
英文短句/例句
1.Investigate the Biogenesis of CML with Small RNA and RNAi;应用小RNA及RNA干扰研究慢性髓性白血病的致病机理
2.Such massive splenomegaly is usually indicative of some myeloproliferative disease such as chronic myelogenous leukemia or myelofibrosis.这样的脾肿大通常预示有骨髓增生型疾病,例如慢性髓性白血病或骨髓纤维化。
3.Systemic review on progress of drug therapy for chronic myelogenous leukemia慢性髓细胞白血病化疗的回顾及进展
4.A slight higher predominance of leukemia in males than females. 3.(慢性骨髓性白血病除外)2.男性罹患率较女性高。
5.Screening and characterization of aptamers of chronic myelognous leukemia K562 cells慢性髓细胞性白血病K562细胞适体的筛选与鉴定
6.Chromosomal abnormalities and clinical significance of bone marrow from 180 patients with CML180例慢性粒细胞白血病骨髓染色体畸变及意义
7.Karyotype Analysis in 119 Patients with Chronic Myeloid Leuke-mia at Blast Crisis119例慢性髓细胞白血病急变期核型分析
8.STI571 for Bone Marrow Purging Ex Vivo in Chronic Myeloid Leukemia;STI571体外净化慢性粒细胞白血病骨髓的实验研究
9.Study on the Expression and Function of GSTpi in Chronic Myelogenous Leukemia CellsGSTpi在慢性髓系白血病细胞中的表达及作用研究
10.Role of p38 mitogen-activated protein kinase in the signal transduction of chronic myelogenous leukemiap38MAPK在慢性髓细胞白血病信号转导中的作用
11.Cytogenetic Analysis of 362 Cases of Chronic Myeloid Leukemia362例慢性髓系白血病的细胞遗传学分析
12.Study on Anti-leukemia Activity of Chronic Myeloid Leukemia Cells Derived Exosome;慢性髓细胞白血病细胞分泌的exosome的抗白血病作用研究
13.Observation on the efficacy of donor leukocyte infusion in acute chronic leukemia and multiple myeloma供体白细胞输注治疗急慢性白血病和多发性骨髓瘤
14.The Primary Syudy of Biologicla Characteristics of Tumor Stem Cells-derived from Bone Marrow of Patients with Chronic Myelogenous Leukemia;慢性粒细胞性白血病患者骨髓源肿瘤干细胞生物学特性的研究
15.HLA Polymorphism Analysis, Identification of HLA Novel Alleles, and Disease Association Study of HLA in Chronic Myeloid Leukemia;HLA多态性分析、新等位基因鉴定及与慢性髓细胞白血病相关性研究
16.The Study about Influence of Protein Tyrosine Phosphatase Superfamily Members PTP1B and Arsenic Trioxide on Chronic Myeloid Leukemia Cells;蛋白酪氨酸磷酸酶PTP1B和三氧化二砷对慢性髓系白血病细胞的影响
17.chronic lymphocytic leukemia慢性淋巴细胞白血病
18.acute transformation of chronic myelocytic leukemia慢性粒细胞白血病急变
相关短句/例句
Chronic myelogenous leukemia慢性髓性白血病
1.Chronic myelogenous leukemia(CML)is a myeloproliferative disorder of pluripotent hematopoietic stem cells,whose cell genetic marker is Philadelphia(Ph) chromosome.慢性髓性白血病(CML)属于多能造血干细胞恶性骨髓增生性疾病,费城(Ph)染色体是CML的细胞遗传学标志,90%以上CML患者骨髓细胞中发现有Ph染色体,经过20年的研究,CML患者的生存愈后得到了显著改善,特别是伊马替尼研制成功给治疗CML带来了很大飞跃。
3)CML慢性髓性白血病
1.CLONING AND EXPRESSION OF CML bcr-abl FUSION GENE FRAGMENT;慢性髓性白血病bcr-abl融合基因的克隆与表达
2.Targeting the tyrosine kinase activity of Bcr-Abl with STI571 is anattractive therapeutic strategy in chronic myelogenous leukemia (CML).慢性髓性白血病是一种起源于造血多功能细胞的恶性增生性疾病,约占成人白血病的15%可分为慢性期﹑加速期﹑急变期,一般病程持续4年左右,随着疾病进展面对治疗逐渐不敏感。
4)chronic myeloid leukemia慢性髓系白血病
1.Quantitative analysis of Sokal s risk index in relation to2therapy protocols:their respective impact on clinical remission of chronic myeloid leukemia;定量分析两种治疗方案与危险指数对慢性髓系白血病临床缓解率的影响
2.This study was aimed to investigate the influences of interferonα(IFN-α)on expressions of CCR7,interleukin10(IL-10)and IL-12p70 in dendritic cells(DCs)from patients with chronic myeloid leukemia(CML).本研究探讨干扰素α(IFN-α)对慢性髓系白血病(CML)来源树突状细胞(DC)表达趋化因子CCR7及分泌IL-10、IL-12P70的影响。
3.The aim of this study was to investigate the effect of nonmyeloablative peripheral blood stem cell transplantation in treatment of chronic myeloid leukemia in chronic phase(CML-CP)and accelerated phasse(CML-AP).本研究观察非清髓造血干细胞移植对慢性髓系白血病慢性期(CML-CP)、慢性髓系白血病加速期(CML-AP)的疗效。
5)chronic myelogenous leukemia慢性髓系白血病
1.Objective To evaluate vascular endothelial growth factor(VEGF) levels in the serum and the bone marrow cells of untreated acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML) patients.目的 探究急性髓系白血病 (AML)与慢性髓系白血病 (CML)血清及CML骨髓细胞VEGF含量的变化。
6)CML慢性髓系白血病
1.CML Cell Line K562 Cell Apoptosis Induced by Mangiferin;芒果甙诱导慢性髓系白血病K562细胞凋亡
2.SphK-1/S1P Signal Pathway in CML Cells;慢性髓系白血病细胞中SphK-1/S1P信号通路的初步研究
3.The specific antigen of chronic myeloid leukemia CML-28 was screened as objective antigen peptide by using magnetic microbeads as vector; the CML-28 epitope sequence (Vltfaldsv) was obtained by antigen epitope prediction software; this epitope was coupled with MHC molecu.以磁性微珠为载体,选取慢性髓系白血病特异性抗原CML28作为目标抗原肽,通过抗原表位预测软件获取CML28表位序列(Vltfaedsv),并以该抗原表位与MHC分子(HLA-A2-Ig)偶联,作为第一信号分子,B7-1分子作为第二信号分子,将两种信号分子同时负载于磁珠表面,构建人工APC复合体;取HLA-A2+的健康骨髓捐赠者骨髓单个核细胞,以磁珠分选出CD8+T淋巴细胞并与人工APC复合体系统共培养。
延伸阅读
慢性淋巴细胞性白血病慢性淋巴细胞性白血病 简称"慢淋"。系免疫无能的小淋巴细胞恶性增殖性疾病。起病比慢粒更缓慢,临床表现更为多样化。早期常无症状或仅有轻度不适,可在体检或血细胞检验时偶然发现。首发症状为淋巴结肿大,其次为乏力、消瘦等。全身症状如发热、盗汗、瘙痒等多为疾病进展的征象。待疾病晚期贫血及出血同时出现。本病预后相对良好,患者又多为老年,所以不必由于淋巴细胞增多而急于治疗。症状明显者,一般采用化疗和放射治疗等。
