1)immunoglobulin heavy chain免疫球蛋白重链
1.Objective:To investigate the application of immunoglobulin heavy chain(IgH) gene rearrangement in the diagnosis and therapy of multiple myeloma(MM).目的:探讨免疫球蛋白重链(IgH)基因重排在多发性骨髓瘤(MM)患者治疗过程中监测的临床意义。
2.Objective To analyze and optimize the gene rearrangement primers of different frame regions (FR) of immunoglobulin heavy chain (IgH) genes by bioinformatic methods and explore the application of these primers in the detection of paraffin-embedded lymphoma tissues.目的通过生物信息学方法分析并优化免疫球蛋白重链(IgH)不同框架(FR)区域基因重排的引物,探索其对石蜡包埋的淋巴瘤组织基因重排检测中的应用。
3.Objective To investigate the clinical significance of the deletion of the long arm of chromosome 13 [del(13q)] and translocation of immunoglobulin heavy chain gene [t(14q)] in multiple myeloma(MM) patients.目的探讨多发性骨髓瘤(MM)患者13号染色体长臂缺失[del(13q)]和免疫球蛋白重链(IGH)基因易位[t(14q)]的临床价值。
英文短句/例句
1.Gene Rearrangement of Immunoglobulin Heavy Chain and the Pathogensis of Mutiple Myeloma免疫球蛋白重链基因重排与多发性骨髓瘤发病机制的研究进展
2.Analysis of the Immunoglobulin Heavy Chain Variable Region Gene Fingerprinting of Human Neonates;新生儿免疫球蛋白重链可变区基因指纹图谱分析
3.A preliminary study on translocation of the immunoglobulin heavy chain gene in KM3 myeloma cell line;骨髓瘤细胞系KM3中免疫球蛋白重链基因易位的初步研究
4.A new method used to screen the human immunoglobulin heavy chain Cγ gene by means of PCR-screening phage library利用PCR筛选噬菌体文库人免疫球蛋白重链Cγ基因的一种新方法
5.cDNA sequence analysis of serum immunoglobulin M heavy chain gene of Tilapia nilotica罗非鱼免疫球蛋白(IgM)重链基因全长cDNA序列分析
6.Purificating of Bovine Immunoglobulin G Light Chain and Heavy Chain and Preparation of Rabbit Anti-Bovine IgG-L and IgG-H Sera;牛免疫球蛋白G轻链、重链分离纯化及其抗血清的制备
7.Immunoglobulin Joining Chain and Heavy Chain Genes and Pattern of Antibody Response in the Chinese Soft-Shelled Turtle Pelodiscus Sinensis中华鳖免疫球蛋白连接链和重链基因与抗体产生规律
8.Mucosal Immune Effect of Group B Streptococcal Surface Immunogenic ProteinB族链球菌表面免疫原性蛋白的黏膜免疫效果
9.Immunoproteomics Analysis of Cell Wall Associated Proteins of Streptococcus Suis Type 22型猪链球菌胞壁蛋白免疫蛋白组学研究
10.diversity region多变区，D区[免疫球蛋白等分子重链的一个高变区]
11.Effect of intravenous immunoglobulin on cell immunity of myasthenia gravis patients免疫球蛋白对重症肌无力细胞免疫机制的影响
12.Prokaryotically Express Virulence Associated Proteins of Streptococcus Suis Type 2 and Evaluation of Immunogenicity and Protective Capacity of Recombination Proteins in Vitro;猪链球菌2型毒力相关蛋白的原核表达及体外试验评估重组蛋白的免疫源性和保护性
13.Immunogenicity Analysis of Surface Protein Fba from Streptococcus Pyogenes;化脓性链球菌表面蛋白Fba的免疫原性研究
14.Expression and Immunogenicity of Streptococcus Uberis GapC Protein;乳房链球菌GapC蛋白的表达及免疫保护研究
15.A Study on Light Chain Sequence of IgM in Five Species of Salmonidae5种鲑科鱼类免疫球蛋白轻链序列分析
16.Ig VL cDNA sequence and diversity analysis of Hucho taimen (Pallas)哲罗鱼免疫球蛋白轻链可变区序列及其多样性
17.Molecular and Functional Characterization of a Novel CXC Chemokine and Immunoglobulin Heavy Chain and Light Chain Isotypes in Large Yellow Croaker大黄鱼CXCL13型趋化因子的鉴定及免疫球蛋白M重链和轻链的分子特征研究
18.Immunoproteomics and Comparative Proteomics of Streptococcus Suis Type 2;猪链球菌2型免疫蛋白组学和比较蛋白组学研究
相关短句/例句
IgVH免疫球蛋白重链可变区
1.Expression of IgVH and B7-1 in proteome of the human colorectal carcinoma cell lines;人大肠癌细胞蛋白质组中免疫球蛋白重链可变区和B7-1的表达
3)IgH免疫球蛋白重链基因
1.Chromosomal translocations involving immunoglobulin heavy chain (IgH) locus at 14q32 are commonly seen in multiple myeloma (MM), which may involve in pathogenesis and associate with prognosis.免疫球蛋白重链基因(immunoglobulinheavychain,IgH)相关的染色体易位是多发性骨髓瘤(multiplemyeloma,MM)中常见的染色体异常,可能与发病有关,与疾病的预后也有一定关系。
4)immunoglobulin heavy chain Fd免疫球蛋白重链Fd段
5)Immunoglobulin M heavy chain免疫球蛋白M重链
6)serum immunoglobulin M heavy chain免疫球蛋白(IgM)重链
1.cDNA sequence analysis of serum immunoglobulin M heavy chain gene of Tilapia nilotica罗非鱼免疫球蛋白(IgM)重链基因全长cDNA序列分析
延伸阅读
免疫球蛋白重链分子式：CAS号：性质： 又称H链，重链。免疫球蛋白单体中的一种多肽链。每条H链由可变区（VH）和恒定区（CH）组成。根据H链恒定区内氨基酸组成排列顺序的不同可将Ig的重链分为五种，即γ（分子量5×104）、α（分子量5.5×104）、δ（分子量6.2×104）、μ（分子量7×104）和ε（分子量7×104）链，其中糖含量分别约为4%，10%，18%，15%和18%。相对于已知五种Ig来说，其分布对应关系如下：IgG（γ），IgA（α），IgD（δ），IgM（μ）和IgE（ε）。其中前三类Ig的H链内有三个恒定区，即CH1、CH2和CH3组成。后两类（IgM和IgE）的H链中有一个VH区和四个恒定区，即CH1至CH4。H链上可变区上有抗原结合点。恒定区既是Ig分子的骨架，又是激活免疫反应的部位之一。由于某种原因，如重链合成过程异常，或轻链合成有缺陷时，血清中会出现重链，这就是重链病。已发现的有α，γ和μ型重链病。
