P53通路,P53 pathway
1)P53 pathwayP53通路
1.The molecular mechanism of regulation of G_1 phase in K562 cells treated with simvastatin in a p53 pathway-dependent manner辛伐他汀依赖p53通路对K562细胞G_1期调节的分子机制
2.Objective To investigate the changes of P53 pathway and cell cycle in K562 cells treated with simvastatin in molecular levels and illustrate the antiproliferative and apoptosis-induced role of P53 pathway in K562 cells when exposed to simvastatin.目的探讨辛伐他汀处理后的P53通路和细胞周期的分子水平变化,以说明P53途径在辛伐他汀抑制K562细胞增殖和诱导细胞凋亡中的作用。
3.[Objective] To investigate the expression of P53 pathway proteins in malignant transformation cells of human bronchial epithelial cells induced by Yunnan tin mine dust.[目的]研究P53通路相关蛋白在云锡矿粉诱导的细胞恶性转化过程中的变化情况。
2)p53-WAF1 pathwayp53-WAF1通路
3)p53 signal pathwayp53信号通路
4)MDM2 p53 pathway regulationMDM2-p53通路调节
5)p53 proteinp53
1.Expression and significance of p53 protein and P-glycoprotein in hepatocelluar carcinoma;原发性肝细胞癌p53蛋白和多药耐药相关蛋白的表达及意义
2.Expression and significance of HB(C)V and p53 protein in hilar cholangiocarcinoma;肝门部胆管癌中乙肝、丙肝病毒感染与p53异常表达的关系及意义
3.Methods The expressions of P33INGI,P53 proteins were measured by immunohistochemistry method(SP method),and apoptesis was detected in 42 cases with ACC, 36 cases with anal canal adenoma (ACA) or anal canal papilloma (ACP),and 40 cases with paraanal inflammatory mass(PMM).目的探讨P33ING1在肛管癌中的表达及与P53和细胞凋亡的关系。
英文短句/例句

1.eIF-5A Regulates p53 and p53-dependent Apoptosis;eIF-5A调控p53p53依赖的细胞凋亡
2.Effect on the Function of 249 Arg to Ser Mutation in the p53 Genep53基因249编码子突变对p53功能的影响
3.Comparative Study between p53 Gene Mutation and Functional Inactivation of p53 in Esophageal Squamous Cell Carcinoma食管鳞癌p53基因突变和p53功能失活的对照研究
4.Serum Anti-p53 Antibodies, Expression of p53 Geneand Differentiation of Primary Hepatic Carcinoma;血清P53抗体、p53基因表达与原发性肝癌的分化程度
5.The Expression and Correlation of P53 s Gene Family P53、P63、P73 in Colorectal Tumors;p53基因家族p53、p63、p73在大肠肿瘤的表达及相互关系
6.Adenovirus mediated p53 gene enhances the sensitivity of gastric cancer cells containing mutant-type p53 to cisplatin人重组p53腺病毒感染p53突变mBGC-823细胞对顺铂敏感性的影响
7.p53 OVEREXPRESSION: A POOR PROGNOSTIC MARKER OF NASOPHARYNGEAL CARCINOMAp53过量表达对鼻咽癌预后的影响
8.p53 overexpression but inactivation in NPC.结论:NPC中p53表达增加而功能异常。
9.Krana,a Novel Negative Regulator of p53;一种新的p53负调控分子Krana的功能研究
10.Experimental Study of p53 Gene Mutations in Keloids;瘢痕疙瘩p53基因突变的实验研究
11.The Inhibitory Effect of Combined p53 and AS Transfecting in HL60 Cell;p53、AS共转染对HL60细胞生长的抑制作用
12.Study on Gastric Carcinoma and mdm2, p53 and p21 Gene Abnormality;胃癌与mdm2、p53及p21基因异常的研究
13.Study of Correlation between HPV16 E6 and p53Arg72Pro Polymorphisms;HPV16 E6与p53 Arg72Pro基因多态性的相关研究
14.The Expression and Significance of p53, MDM2 and PCNA in Psoriasis;p53、MDM2和PCNA在银屑病中的表达及意义
15.The Study on the Roles of Ceramide and p53 in the Apoptosis Induced by AngⅡ;Ceramide和p53介导AngⅡ诱导细胞凋亡的研究
16.Expression of PCNA、Ki-67 and P53 in Nonsmall Cell Lung Cancer;非小细胞肺癌PCNA、ki-67和p53表达的研究
17.Effects of p53 Gene on Drug Resistance in Humanlung Cancer Cell Lines;p53基因对人肺癌细胞系耐药性的影响
18.The Relationship Among HPV16/18、HSP70、p53、c-myc and Cervical Cancer;HPV16/18、HSP70、p53、c-myc与宫颈癌的相关性研究
相关短句/例句

p53-WAF1 pathwayp53-WAF1通路
3)p53 signal pathwayp53信号通路
4)MDM2 p53 pathway regulationMDM2-p53通路调节
5)p53 proteinp53
1.Expression and significance of p53 protein and P-glycoprotein in hepatocelluar carcinoma;原发性肝细胞癌p53蛋白和多药耐药相关蛋白的表达及意义
2.Expression and significance of HB(C)V and p53 protein in hilar cholangiocarcinoma;肝门部胆管癌中乙肝、丙肝病毒感染与p53异常表达的关系及意义
3.Methods The expressions of P33INGI,P53 proteins were measured by immunohistochemistry method(SP method),and apoptesis was detected in 42 cases with ACC, 36 cases with anal canal adenoma (ACA) or anal canal papilloma (ACP),and 40 cases with paraanal inflammatory mass(PMM).目的探讨P33ING1在肛管癌中的表达及与P53和细胞凋亡的关系。
6)p 53p53
1.Study on the feasibility of using magnetic iron oxide nanoparticles as wt-p 53 gene carrier for transfection of lung cancer cells;氧化铁纳米颗粒作为p53基因载体并转染肺癌细胞的可行性研究
2.Objective To study the expression of p 53、rasp 21、p 16 in NIH/3T3 cell treated by VOCs(the compounds of benzene and formaldehyde).目的探讨苯、甲醛混合物对NIH/3T3细胞中p53、rasp21、p16表达的影响。
3.Objective To evaluate the expression and clinical significance of tumor suppressor gene TGFβ 1 and oncogene P 53(mutant) in the progression of cervical carcinoma, and to investigate their relations between TGFβ 1 and P 53.目的检测转化生长因子β1及P53在宫颈癌中的表达,探讨P53和TGFβ1在宫颈癌发生发展中的作用,及它们之间的相关性。
延伸阅读

开辟通路开辟通路breaching kaiPi tonglu开辟通路(br eaching)在障碍区中排除障碍物以开辟通道的行动。工程保障任务之一。包括陆上开辟通路和水中开辟通路。目的是确保人员、车辆、舰艇、登陆输送工具等安全通过障碍区。 中国战国时期,在进攻城池的作战中,已用人工清除鹿碧、铁羡黎等障碍物。明代中后期,采取了爆破法排除地雷、水雷。第一次世界大战时期,广泛采取了爆破法在地雷、铁丝网等障碍区中开辟通路。第二次世界大战时期,还使用炮兵、航空兵等火力开辟通路,严密组织火力、烟幕掩护开辟通路。 开辟通路须运用各种力量,充分发挥工程兵的骨干作用;预先查明障碍物配系和敌火力控制等情况,做好开辟通路的各项准备;根据任务、时间、敌情选择开辟的方法,明确规定开辟通路的数量和宽度。使用人工和机械开辟通路时,还须周密组织火力与烟幕掩护,尽量利用能见度不良时实施。基本方法有爆破法、机械法和人工法。有时炮兵、航空兵、舰艇部队的火力也用于开辟通路。通常以扫雷滚、爆破器、探雷器和手工作业排除地雷、铁丝网;用推土装置和爆破装置排除壕、坑、桩紫等障碍物;使用扫雷舰艇、直升机和潜水员排除水中障碍物。在沾染区和化学障碍物中开辟通路须穿戴防护器材;排除电障碍物、火障碍物时须防止触电和烧伤。开辟通路时,根据情况,灵活运用各种手段和器材,采取秘密开辟与强行开辟相结合的方法实施。秘密开辟通常在火力准备前进行,强行开辟在火力准备开始后实施。通路开辟完毕,进行标示和伪装,并以火力加以控制。当开辟的通路被敌封闭后,重新组织开辟。 随着障碍物的发展,障碍物设置能力的增强,开辟通路的任务将更加艰巨,对专业技术的要求更高;由于大量使用高效、遥控排除障碍物的装备器材,作业速度将提高。(陈运鸿)使用爆破器开辟通路 李子亮摄