PML/RARα融合基因,PML/RARα fusion gene英语短句,例句大全

PML/RARα融合基因,PML/RARα fusion gene
1)PML/RARα fusion genePML/RARα融合基因
1.PML/RARα fusion gene was detected by using reverse-transcription polymerase chain reaction (RT-PCR) technique.为了了解CD117/CD11b在急性早幼粒白血病细胞初诊及治疗后的表达变化,探讨其表达变化对APL诊断和预后的意义,采用CD45/SSC双参数散点图设门方法进行三色或四色流式细胞术细胞表面及浆内分化抗原分析,应用RT-PCR技术检测骨髓中PML/RARα融合基因的mRNA表达。
2.Detection of the PML/RARα fusion gene by RT PCR in acute promyelocytic leukemia (APL) blasts is not only critical to commence promptly the specific therapy with all trans retinoic acid (ATRA) or arsenic trioxide (As 2O 3), but also essential for the definition of PML breakpoint type and subsequent monitoring of minimal residual disease (MRD).在急性早幼粒细胞白血病 (APL)细胞中迅速、准确检出PML/RARα融合基因对于及时应用全反式维甲酸 (ATRA)或亚砷酸 (As2 O3 )提高诱导缓解率、减轻出血导致的早期死亡至关重要 ,但目前临床上采用的嵌套式RT PCR方法繁琐且费时 ,亟待改进以满足临床APL快速、准确诊断的需要。
3.A new kind of sandwich-type DNA electrochemical biosensor is designed to detect PML/RARα fusion gene in acute promyelocytic leukemia.基于急性早幼粒细胞白血病(APL)中PML/RARα融合基因的碱基序列,设计了新型的锁核酸(LNA)修饰寡核苷酸作为捕获探针和信号探针,研究出一种基于"三明治"传感模式的电化学生物传感器对PML/RARα融合相关基因进行检测。

英文短句/例句

1.Detection of expression of PML/RARα fusion gene in acute premyeloid leukemia patients with real-time RT-PCR初治APL患者PML/RARα融合基因表达
2.Detection of PML/RARα Fusion Gene in Acute Promyelocyte Leukemia急性早幼粒细胞白血病PML/RARα融合基因的检测
3.Detection of PML/RARα Fusion Gene Transcripts in Patients with APL Using Real-time Quantitative PCR实时定量PCR检测急性早幼粒细胞白血病患者PML/RARα融合基因转录本
4.The detection of PML-RARα fusion gene in promyelocytic leukemia to monitor minimal residual diseasePML/RARα融合基因检测早幼粒细胞白血病微小残留病
5.The Research of Specific T Cells Immunological Reaction and DNA Vaccine Construction Based on PML-RARα Fusion Gene;基于PML-RARα融合基因的特异性T细胞免疫反应和基因疫苗构建研究
6.Detect PML-RARα fusion gene and analyse its clinical significance in acute promyelocytic leukemia动态监测PML-RARα融合基因对急性早幼粒细胞白血病的临床意义
7.Preparation of DNA Biosensor for Detection of PML-RARα Fusion Gene in Acute Promyelocytic Leukemia检测急性早幼粒细胞白血病PML-RARα融合基因的DNA传感器研制
8.Effect of SEA on the Distribution and Clonal Expansion of TCR Vβ Subfamilies and the Cytotoxicity of T Cells Stimulated by PML-RARα Peptide.;超抗原SEA对PML-RARα融合多肽诱导TCR Vβ亚家族T细胞克隆性的影响
9.The Study on Molecmle Mechanism of NE Cleaved PML-RARα in APL PathogenesisNE介导的PML-RARα融合蛋白裂解产物在APL发生中的分子机制研究
10.Study on Construction and Expression of the Eukaryotic Coexpression Plasmid Containing PML-RARα Gene and Human GM-CSF/IL-2 Gene;PML-RARα与hGM-CSF/hIL-2基因的真核双表达载体构建和表达研究
11.Detection of PML-RARa Transcripts in Acute Promyelocytic Leukemia by Real-time Quantitative Reverse Transcriptase Polymerase Chain Reaction;实时定量RT-PCR检测急性早幼粒细胞白血病PML-RARa融合基因
12.Effect of Immune Response Induced by APL Cells and PML-RARα Vaccine in Vitro and in Vivo;APL细胞和PML-RARα疫苗诱导体内外免疫应答的研究
13.fusogenic peptide融合肽，基因融合肽
14.Preparation of Polyclonal Antibody for Human PML Gene and Identification Its Subnuclear Localization人PML基因多克隆抗体的制备及其亚细胞结构定位的研究
15.Localization of Rice CesA4 Promoter with GUS-Fusion水稻CesA4基因启动子与GUS基因融合表达
16.Construction and Expression of umcel5N-CBM Encoding Fused Endoglucanase Catalytic Domain and Carbohydrate-Binding Module and Characterization of the Fusion Enzyme融合基因umcel5N-CBM的构建、表达及融合酶性质分析
17.Numerical Simulation of Conformal PML Based on Orthogonal Trajectory Method基于正交轨迹的共形PML数值仿真方法
18.Gene Cloning and Fusion Expression of Cervus nippon FSHβ-subunit in E. coli梅花鹿FSHβ亚基基因克隆与融合表达

相关短句/例句

PML/RARαfusion genePML/RARα融合基因
1.Methods FISH was used to detect the AML1/ETO fusion gene and/or PML/RARαfusion gene in 10 AML-M_2 cases,19 AML-M_3 cases and 11 AML cases undetermined as AML-M_2 or AML-M_3 by routine morphology,cytochemical staining and immunophenotyping.方法对初发的经骨髓常规形态学、细胞化学染色和免疫分型初步诊断的10例AML-M2、19例AML-M3,11例AML不能确定为M2或者M3的患者,进行FISH技术检测AML1/ETO和/或PML/RARα融合基因,进而协助诊断和指导治疗。
3)PML-RARα fusion genePML-RARα融合基因
1.A DNA electrochemical sensor was prepared by fixing amino group-modified ssDNA probe with particular DNA sequence of PML-RARα fusion gene in acute promyelocytic leukemia(APL) on the surface of a glassy carbon electrode using covalent bond technology.利用共价键合法,将氨基修饰的具有急性早幼粒细胞白血病PML-RARα融合基因特异性的单链DNA探针固定在玻碳电极表面,构成急性早幼粒细胞白血病DNA传感器(急粒DNA传感器)。
4)PML-RARα genePML-RARα基因
1.Aim: To construct a eukaryotic coexpression plasmid containing PML-RARα gene and human GM-CSF(hGM-CSF) gene,which was expected to be used as a modified DNA vaccine for acute promyelocytic leukemia.目的:构建急性早幼粒细胞白血病(APL)PML-RARα基因与人粒巨噬细胞集落刺激因子(hGM-CSF)基因真核双表达载体,为利用DNA疫苗治疗APL奠定基础。
2.Objective To construct the PML-RARα gene recombinant plasmid, which is expected to be used as a modified DNA vaccine for acute promyelocytic leukemia.目的构建PML-RARα基因重组表达质粒,为发展PML-RARα基因疫苗提供实验依据。
5)RARαfusion geneRARα融合基因
1.This study was purposed to establish a real-time quantitative reverse transcript polymerase chain reaction (RQ-PCR) for detection of PML/RARαfusion gene transcrips in patients with acute promyelocytic leukemia and to explore the relationship between the expression level of PML /RARa fusion gene transcript and the clinical status or efficacy of the therapy in APL.这种异常可以累及维甲酸受体α(RARα, Retinoic acid receptorα), t ( 15; 17)造成早幼粒细胞白血病( PML, promyelocytic leukemia)基因与RARα重排,形成PML/RARα融合基因。
6)PML-RARα fusion proteinPML-RARα融合蛋白
1.5 μmol/L As2O3 was incubated for 24 hours and 48 hours,then total protein was extracted,expressions of subunit β1 and PML-RARα fusion protein were determined by Western blot.5μmol/LAs2O3干预NB4细胞,分别提取干预24小时及48小时后的总蛋白;以Western blot检测蛋白酶体β1亚基及PML-RARα融合蛋白表达变化,并进行灰度分析。