Aurora激酶抑制剂,Aurora kinase inhibitor
1)Aurora kinase inhibitorAurora激酶抑制剂
1.Aurora kinase inhibitors are new member of the family of targeted agents.Aurora激酶抑制剂是分子靶向治疗的新领域,Aurora激酶不仅与肿瘤密切相关,而且Aurora激酶抑制剂也显示了很强的抗肿瘤能力,部分抑制剂都进入了Ⅰ期临床实验。
2.Recent work indicates that an Aurora kinase inhibitor MK-0457 (VX-680),a small-molecule inhibitor of Aurora kinases A,B,C and BCR-ABL,FLT-3,JAK-2,can block the progression of cell growth cycle,causing apoptosis in a range of human tumors.近年来研究的一种Aurora激酶抑制剂MK-0457(VX-680),是Aurora激酶A、B、C及BCR-ABL、FLT-3、JAK-2等多种激酶的小分子抑制剂。
英文短句/例句

1.The anticancer role of aurora kinase inhibitorsAurora激酶抑制剂的抗肿瘤作用
2.Research Progress on Aurora Kinase Inhibitor MK-0457 in Therapy for Some Hematological Malignancies--ReviewAurora激酶抑制剂MK-0457治疗多种恶性血液病的研究进展
3.The Progress of Aurora Kinase and its inhibitorsAurora激酶及其抑制剂研究状态综述
4.New Advances in Aurora Kinase and Its Anti-tumor InhibitorsAurora蛋白激酶及其抑制剂的研究进展
5.Screening of potential small-molecular inhibitor of human Aurora-B kinase using budding yeast酵母模型在Aurora-B激酶抑制剂筛选中的应用
6.The Study of Gene Therapy for Hepatocellular Carcinoma by RNA Interference Targeting Aurora Kinase AsiRNA抑制Aurora-A激酶的表达治疗肝细胞肝癌的实验研究
7.Anticancer activity of FB2,a Src kinase inhibitor,on prostate cancerSrc激酶抑制剂FB2抗前列腺癌作用研究
8.Research and development of inhibitors of IκB kinase-βIκB激酶-β抑制剂的研究与开发
9.Advances in Study of Glycogen Synthase Kinase-3β and Its Inhibitors糖原合成酶激酶-3β及其抑制剂研究进展
10.3D-QSAR study for novel inhibitors of mitogen activated protein kinase-activated protein kinase 2促分裂原活化蛋白激酶激活的蛋白激酶-2全新抑制剂的3D-QSAR研究
11.The Mechanism of Increasing Outflow Facility by Rho-Kinase Inhibition with Y27632;Rho激酶抑制剂(Y27632)对房水流畅率的作用及其机制
12.The Experimental Study of Rho Kinase Inhibitor Y-27632 on the Mechanism of Lowering the Intraocular Pressue;Rho激酶抑制剂Y-27632降眼压机制的实验研究
13.Intraocular Pressure Lowering Effects of the Rho-kinase Inhibitor H-1152;Rho激酶抑制剂H-1152降眼压作用的实验研究
14.The Study of Reversal of Multidrug Resistance in Human Renal Cell Carcinoma by Inhibition Agents of Protein Kinase C Alpha;蛋白激酶C alpha抑制剂逆转肾癌多药耐药的研究
15.Molecular Modelling Study on Structure and Function of Protein Kinase A and Its Inhibitor;蛋白激酶A结构、功能及抑制剂的分子模拟研究
16.Modification and Inhibition of Arginine Kinase from Locust;蝗虫精氨酸激酶的活性中心及其抑制剂研究
17.Design, Synthesis and Screening of CP690550 and Janus Kinase 3 Inhibitors;Jak3激酶抑制剂CP690550及其衍生物的设计、合成与筛选
18.Design, Synthesis and Screening of the Small Molecular c-Fms Kinase Inhibitors小分子c-Fms激酶抑制剂的设计、合成与筛选
相关短句/例句

Aurora-B kinase inhibitorAurora-B激酶抑制剂
3)Aurora-A kinaselAurora-A激酶
4)Aurora kinaseAurora激酶
1.Vx-680,a small molecule inhibitor of the Aurora kinases,suppresses head and neck tumor growth in vitro;Aurora激酶抑制剂VX-680对头颈肿瘤细胞增殖的影响
2.Aurora kinase,a vital regulator for cellular mitosis affecting the process of cell cycle,is regarded as a new target for the anti-tumor drugs.Aurora激酶家族是细胞有丝分裂期重要的调节因子,可影响细胞周期进程,是抗肿瘤药物的新靶点。
3.Recent studies have found aberrant expression of Aurora kinases in a variety of human solid tumors and hematological malignancies,suggesting they are important targets for anti-cancer drugs.Aurora激酶家族是苏氨酸/丝氨酸激酶,在有丝分裂的染色体排列,分离和胞质分裂中起重要作用。
5)Kinase inhibitor激酶抑制剂
1.The feasibility of application of reverse docking method to the selectivity studies of protein kinase inhibitors探索应用反向对接技术研究蛋白激酶抑制剂选择性的可行性
2.The signal transduction pathway of multi-target kinase inhibitors as anticancer agents in clinical use or in phase Ⅲ已上市和部分正在Ⅲ期临床开发中的多靶点激酶抑制剂抑酶谱及信号传导通路分析
3.A number of diseases are linked to overactivation of protein kinases and a lot of kinase inhibitors have been developed.由于蛋白激酶的异常激活导致了许多疾病,激酶抑制剂成为当今医药领域的研究热点。
6)protein kinase inhibitor蛋白激酶抑制剂
延伸阅读

[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式:C16H16ClN3O3S分子量:365.5CAS号:26807-65-8性质:暂无制备方法:暂无用途:用于轻、中度原发性高血压。