1)VEGF antisense oligonucleotideVEGF反义核酸
英文短句/例句
1.MRI Study on Vascular Endothelia Growth Factor Antisense Gene Regulation for Leptomeningeal Metastasis;VEGF反义核酸调控脑脊液源性转移的磁共振监测
2.Effect of VEGF Anti-sense cDNA on Tumor Radiotherapy and Its Correlative Pathological Study and MR Imaging Detection;VEGF反义核酸对肿瘤放射治疗的影响及其相关基础研究和MRI监测
3.The Effect of Antisense VEGF Vector on Cell Proliferation and Angiogenesis in Pancreatic Cancer;VEGF反义核酸对胰腺癌增殖及血管生成影响的研究
4.MRI study on antisense VEGF cDNA regulation for metastasis from CSFVEGF反义核酸对兔VX2瘤脑脊液源性转移调控的MRI监测
5.Effect of VEGF antisensenucleic acids united radiation therapy on nude mouse transplantation tumor uterine cervix cancerVEGF反义核酸联合放射治疗对裸鼠移植瘤宫颈癌的作用
6.Effects of Antisense Oligodeoxynucleotides Targeting VEGF mRNA on Drug-sensitivity of Leukemic Cells;VEGF mRNA反义核酸对白血病细胞药物敏感性的影响
7.Experimental Study on Prostate Carcinoma Treated with Vascular Endothelial Growth Factor Antisense Oligodoxynucleotide;VEGF反义寡核苷酸治疗前列腺癌的实验研究
8.Inhibitory Effect of VEGF Antisense Phosphorothioate Oligodeoxynucleotides on the Growth of Human Tongue Cancer Xenografts in Nude MiceVEGF反义寡核苷酸对舌鳞癌影响的实验研究
9.The effect of VEGF antisense oligodeoxynucleotides on apoptosis of leukemia cellsVEGF反义寡核苷酸对白血病细胞凋亡的影响
10.The Effect of VEGF Antisense Oligodeoxynucleotides Transfection on Angiogenesis in Gallbladder Carcinoma;VEGF反义寡核苷酸转染对胆囊癌肿瘤血管生成影响的研究
11.The Experimental Study of Inhibition on Angiogenesis in Walker-256 Hepatoma in Rats by VEGF Antisense Oligonucleotides Loaded Nanoparticles;载VEGF反义寡核苷酸纳米粒抑制大鼠肝癌新生血管作用的实验研究
12.Effects of VEGF-C Antisense Oligodeoxynucleotide on the Biological Behavior of Human Ovarian Cancer SKOV3 Cell Line;VEGF-C反义寡核苷酸对卵巢癌细胞株SKOV3生物学行为的影响
13.The Inhibitory Effects of VEGF-C and COX-2 Antisense Oligodeoxynucleotides Combined on Lymphangiogenesis in Breast Carcinoma;COX-2与VEGF-C反义寡核苷酸联合抑制裸鼠乳腺癌淋巴管生成的研究
14.A Study on Inhibition Expression of VGEF by Antisense Oligonucleotides and Its Biological Effect on LA-N-5 Cells;反义寡核苷酸抑制LA-N-5细胞VEGF表达及生物效应的研究
15.Experimental Study on Inhibition of VEGF Antisense Oligonucleotides on Bladder Carcinoma in Nude Mice Mediated by Ultrasound Microbubble;超声微泡介导VEGF反义寡核苷酸抑制裸鼠膀胱肿瘤生长的实验研究
16.Inhibitory Effect of VEGF Antisense Oligonucleotide on Human Colorectal Cancer Cells under Hypoxia in Vitro反义VEGF寡核苷酸对体外缺氧条件下生长的大肠癌细胞的抑制作用
17.Expression and Interaction of Survivin mRNA and VEGF mRNA in Osteosarcoma Cell after Transfection of ASODN by Lipidosome脂质体介导反义核苷酸转染骨肉瘤细胞后Survivin与VEGF表达的相互影响
18.VEGF Antisense Oligonucleotides in Combination with DDP Inhibited the Growth of Osteosarcoma Nude ModelVEGF反义寡核苷酸与顺铂联合治疗抑制裸鼠骨肉瘤的生长
相关短句/例句
VEGF antisense RNAVEGF反义RNA
1.The inhibitory of VEGF antisense RNA on the proliferation and apoptosis of C6 cells in vitro were obserced.目的探讨VEGF反义RNA对C6鼠胶质瘤细胞体外作用。
2.Methods TE-1cells transfected with VEGF antisense RNA、pcDNA3.目的探讨VEGF反义RNA对食管癌细胞在裸鼠体内生长的影响。
3)antisense VEGF反义VEGF
1.Objectives: Use antisense VEGF to reduce the immunosuppression induced by tumor and enhance the antithumor effect of IL-2.目的 :本研究旨在探讨腺病毒介导的反义VEGF降低肿瘤诱导的免疫抑制及增强IL 2的抗肿瘤效果。
4)antisense VEGF gene反义VEGF基因
1.To study the inhibitory role of antisense VEGF gene on the growth of tumor cells and apoptosis of the cells induced by antisense VEGF gene, the pcDNA3.结果证明,反义VEGF基因确有抑制神经母细胞瘤生长的作用,电镜下观察到细胞出现凋亡形态,ELISA结果表明VEGF的表达显著降低。
5)Antisense[英][,?nti'sens][美][,?nti's?ns, ,?nta?-]反义核酸
1.Human Antisense VEGF_(121) Expression Vector Inhibits Angiogenensis Potential of Pancreatic Cancer Cell in vitro;血管内皮生长因子_(121)反义核酸抑制人胰腺癌细胞体外促血管生成能力
2.Observation in the Antisense TRP1 Transfected Melanocytes and Malignant Melanoma Cells by Microscope and Electron Microscope;TRP-1反义核酸转染黑素细胞 黑素瘤细胞的光镜及电镜观察
3.Influence on Apoptosis in the Antisense TRP-1 Transfected Melanocytes and Malignant Melanoma Cells;TRP-1编码基因反义核酸对良恶性黑素细胞凋亡的影响
6)antisense oligonucleotide反义核酸
1.Effects of intracellular and extracellular concentrations of calcium ions in odontoblast cell line MDPC-23 by antisense oligonucleotide against dentin matrix protein 1;牙本质基质蛋白1基因反义核酸对MDPC-23细胞内、外钙离子浓度的影响
2.Effect of antisense oligonucleotide against dentin matrix protein 1 on ALP ase activity and mineralization ability of odontoblast cell line MDPC-23;牙本质基质蛋白1基因反义核酸对MDPC-23细胞碱性磷酸酶活性和矿化能力的影响
3.Objective To investigate the effect of nuclear factor kappa B(NF-κB) antisense oligonucleotide (AS-ON) on cardiac muscle myosin isoenzymes (MI) and serum cytokines (TNF-α, IL-1β, Fas) expressions in rat models of chronic heart failure.目的:探讨核转录因子(nuclear factor kappa B, NF-κB)反义核酸(antisense oligonucleotide,AS-ON)对慢性心力衰竭(chronic heart failure,CHF)病程心肌肌凝蛋白同功酶(myosin isoenzyme,MI)和细胞因子肿瘤坏死因子α(tumor necrosis factorα,TNF-α)、白细胞介素-1β(interleukin-1β,IL-1β)和Fas的影响。
延伸阅读
VEGF分子式:CAS号:性质:又称血管通透因子(vascular permeability factor)。1989首先从牛垂体滤泡状细胞培养液中分离纯化。有四种不同形式,成熟单体,分别为121,165,189和206个氨基酸,目前分离得到的VEGF,均由两个相同多肽链通过二硫键构成的同源二聚体,亚基分子量18 000~24 000,总蛋白分子量34 000~46 000。蛋白质表面有许多阳离子,呈强碱性,等电点高,对酸碱热稳定。VEGF是一类糖蛋白,可与肝素结合,多糖链仅与其分泌功能有关,与生物活性无关。VEGF 121/165为可溶性分泌蛋白。VEGF 189/206几乎都结合在质膜或基底膜上的含有肝素的蛋白聚糖上。四种VEGF的生物活性无明显差异。VEGF是一类多功能生长因子,能特异性作用于血管内皮细胞,强烈促进其增殖,促进血管形成,并有升高血管通透性的作用。多种细胞有分泌VEGF的功能,并通过旁分泌方式作用于血管内皮细胞。对血管内皮细胞的促有丝分裂作用十分强烈,可明显促进血管生成,能引起血管通透性增加,且是最强烈的引起血管通透性增加的物质。1nmol/L即可起作用,为组胺的50 000倍。用于心血管疾病、肿瘤、创伤修复等。
