1)second tyrosine kinase domainFLT3基因突变
1.This study was aimed to investigate the frequency of FMS-like tyrosine kinase 3(FLT3) mutations including internal tandem duplication(ITD) mutation of juxtamembrane region and point mutation of the second tyrosine kinase domain(TKD) in acute myeloid leukemia(AML) patients and its clinical significance.结论:FLT3基因突变是AML患者中常见的突变,FLT3-ITD突变较FLT3-TKD点突变发生率高,FLT3-ITD有突变的AML患者预后差;FLT3-TKD点突变对预后的影响不明显。
英文短句/例句
1.FMS-like Tyrosine Kinase 3 Gene Mutations in Acute Myeloid Leukemia急性髓系白血病FLT3基因突变研究
2.Detection of FLT3 Gene Mutation in Malignant Hematopoietic Patients and Its Clinical Significance;恶性血液病FLT3基因突变的检测及临床意义
3.Study of FLT3 Gene Mutations in Patients with Acute Promyelocytic Leukemia;急性早幼粒细胞白血病患者FLT3基因突变的研究
4.The Expression of SSBP2 Gene and Detection of FLT3 Gene Mutation in Acute Myeloid Leukemia Patients;急性髓系白血病患者SSBP2基因表达分析及FLT3基因突变检测
5.Mutations and Expression of FMS-Like Tyrosine Kinase 3 Gene in Patients with Acute Promyelocytic Leukemia and Its Clinical Significance;急性早幼粒细胞白血病患者FLT3基因突变与表达及其临床意义
6.FLT3 Mutation in Patients with Acute Lymphoblastic Leukemia and Its Clinical Significance急性淋巴细胞白血病FLT3基因突变的发现及临床意义
7.The detection of FLT3 and FLT3/ITD gene mutation by polymerasechain reaction single-strand conformation polymophism in acute myeloid leukemia patientsPCR-SSCP检测急性髓系白血病患者FLT3基因及FLT3/ITD基因突变
8.Study of FLT3 and DCK Gene Mutations in Acute Leukemia by Denaturing HPLC;应用变性高效液相色谱方法研究急性白血病FLT3、DCK基因突变
9.Prevalence and Clinical Significance of FLT3 Internal Tandem Duplication Mutation in Elderly Acute Myeloid Leukemia老年急性髓细胞白血病FLT3-ITD基因突变检测及临床研究
10.Research of NPM1 and FLT3-ITD Gene Mutations in Adult Patients with Acute Myeloid Leukemia成人急性髓细胞白血病NPM1与FLT3-ITD基因突变的研究
11.Detection and clinical significance of FLT3 internal tandem duplication mutation in acute myeloid leukemia急性髓细胞白血病FLT3-ITD基因突变的检测及其临床意义
12.The Clinical Prevelence of FLT3 Mutations in Acute Leukemia;FLT3突变在急性白血病中的临床意义
13.Research of FLT3/ITD Mutation in Acute Myelocytic Leukemia;急性髓细胞白血病FLT3/ITD突变的研究
14.Gene cloning, expression and purification of Human FLT3 Ligand;人FLT3 Ligand基因的克隆、表达与产物纯化
15.A Study of Flt3 Gene Expression and Its Significance in Acute Leukemia;Flt3基因在急性白血病中的表达及其意义的研究
16.RNAi-induced Inhibition of FLT3 Expression and Induction of Apoptosis in HL-60 Cells;RNAi抑制HL-60细胞FLT3基因表达及诱导凋亡的研究
17.FLT3 Length Mutations, FLT3 Expression and Their Clinical Implications in Patients with Myeloid Leukemia;FLT3长度突变及表达水平在急性髓系白血病中的临床意义
18.Expression of FLT3 Internal Tandem Duplication in Pediatric Patients with Acute Myeloid Leukemia and Its Correlation with Multidrug ResistanceFLT3-ITD突变在儿童急性髓性白血病中的表达及其与多药耐药的关系
相关短句/例句
FLT3/ITD mutationFLT3/ITD基因突变
1.The value detection of FLT3 gene and FLT3/ITD mutation in myelodysplastic syndromes;骨髓增生异常综合征患者FLT3基因及FLT3/ITD基因突变的检测及价值
2.Results The expression of FL T3 gene were detected in 43 AML patients with agarose gel and single-strand conformation polymorphism eletrophoresis;There was no FLT3/ITD mutation with agarose gel eletrophoresis,but FLT3/ITD mutation was detected in 15 cases(35%)with single-strand conformation polymorphism gel eletrophoresis.方法采用多聚酶链反应(PCR)联合单链构象多态性(SSCP)方法检测43例不同免疫分型AML患者DNA水平FLT3基因及FLT3/ITD基因突变。
3)FLT_3 mutationsFLT3突变
1.Objective:To investigate the FLT_3 mutations in leukemia patients by peripheral blood and indicate the relationship between FLT_3 mutations and the pathogenesis of leukemia.结论Flt3基因突变和白血病发生、发展相关,外周血可以替代骨髓检测FLT3突变;FLT3-ITD阳性患者化疗缓解率低、易复发、预后差;外显子14、L567突变点是否为FLT3一个新的突变热点需进一步研究。
4)FLT3-ITD mutationFLT3-ITD突变
5)FLT3 geneFLT3基因
1.The value detection of FLT3 gene and FLT3/ITD mutation in myelodysplastic syndromes;骨髓增生异常综合征患者FLT3基因及FLT3/ITD基因突变的检测及价值
2.This study was aimed to explore the role of FLT3 gene in AML pathogenesis and its significanse for detection of MRD.本研究旨在探讨FLT3基因在AML发病中的作用及对微小残留病(MRD)检测的意义。
6)Flt3-LgeneFlt3-L基因
延伸阅读
[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式:C16H16ClN3O3S分子量:365.5CAS号:26807-65-8性质:暂无制备方法:暂无用途:用于轻、中度原发性高血压。
