1)hTERTmRNA端粒酶hTERTmRNA
1.In this study,in order to identify the expression of hTERTmRNA and p53 gene in NSCLC tissues and normal lung tissue,and make clear thei本试验采用原位杂交和免疫组化方法检测端粒酶hTERTmRNA、p53蛋白在非小细胞肺癌(NSCLC)及癌旁正常肺组织中的表达情况,探讨端粒酶hTERTmRNA在非小细胞肺癌组织中的表达及其与p53的相关性。
英文短句/例句
1.Expression and Significance of hTERT mRNA in Non-small Cell Lung Cancer and Its Relation to p53端粒酶hTERTmRNA表达在非小细胞肺癌中的意义及其与p53的相关性
2.Effects of telomerase activity and hTERTmRNA expression in hepatocellular carcinoma cells treated by glycodeoxycholic acid甘氨脱氧胆酸钠对人肝癌细胞端粒酶活性及其hTERTmRNA表达的影响
3.Telomere and Telomerase--A New Juncture for People to Surmount Cancer;端粒与端粒酶——人类攻克癌症的新契机
4.Researches on the Functional Analysis of PinX1 Gene in Telomerase/Telomere RegulationPinX1在端粒酶/端粒调控中的作用分析
5.Telomere,telomerase and their biological senses端粒和端粒酶的发现及其生物学意义
6.Study of Telomere and Telomerase in Tumor and cell ageing端粒、端粒酶在肿瘤、细胞衰老中的研究
7.To design HDV ribozyme for human telomerase RNA( hTR) component, and observe its inhibition for telomerase activity. Pseudoknotted g.设计针对端粒酶的HDV核酶,观察其对端粒酶活性抑制。
8.Inhibition of Telomerase Activity by siRNA Targeted to Human Telomerase Reverse Transcriptase;人端粒酶反转录酶siRNA抑制肿瘤细胞端粒酶活性的研究
9.Telomerase Activity and the Expression of Human Telomerase Reverse Transcriptase in Condyloma Acuminata Tissues;尖锐湿疣组织中端粒酶活性和端粒酶逆转录酶表达的研究
10.The guidance of telomerase activity and human telomerase reverse transcriptase mRNA expression on the diagnosis and treatment of orbital tumor端粒酶活性及端粒酶逆转录酶mRNA的表达对眼眶肿瘤的诊治
11.Purification and Characterization of Telomerase Core Enzyme of Saccharomyces Cerevisiae;酵母端粒酶核心酶的纯化和定性研究
12.Expression of telomerase reverse transcriptase mRNA in oral lichen planus and oral squamous cell carcinoma端粒酶逆转录酶mRNA在OLP和OSCC中的表达
13.Cloning of the Human Telomerase Reverse Transcriptase Core Promoter人端粒酶逆转录酶核心启动子的克隆
14.Effect and Mechanism of Selenium, Zinc and Lead on Cellular Telomere and Telomerase;硒锌铅对细胞端粒和端粒酶的作用及机理研究
15.Cloning and sequence analysis of 3′ end cDNA of E.tenella telomerase reverse transcriptase geneE.tenella端粒酶逆转录酶基因3′端序列的克隆及分析
16.The Human Pif1 Encodes a RecD-like Helicase That Regulates Telomere Elongation Through Inhibition of Telomerase Activity;人的类RecD解旋酶Pif1通过抑制端粒酶活性调控端粒延伸
17.Effect of Telomerase Antisense Oligodeoxynucleotides on Telomerase Aitivity and Growth of Eca-109 Cell Line;端粒酶反义寡核苷酸对食管癌细胞端粒酶活性及细胞生长的影响
18.Construction of Screening Model for Telomerase Inhibitors Contained Human Telomerase RNA Mutant含人端粒酶RNA突变体的端粒酶抑制剂筛选模型的构建
相关短句/例句
hTERT mRNAhTERTmRNA
1.Objective This study was designed to investigate the significance of hTERT mRNA in breast carcinogenesis and to explore the diagnostic efficacy, and to study the effect of tumor suppressor gene p53 on the expression of hTERT mRNA.目的探讨端粒酶hTERTmRNA表达在人乳腺癌发生、发展中的意义,观察肿瘤抑制基因p53与hTERTmRNA表达的关系。
2.Methods Reverse transcription-polymerase chain reaction (RT PCR) method was employed to detect the hTERT mRNA and MDR mRNA in cancer tissues and para tumor liver tissues in 58 paticats with HCC.方法 检测 5 8例HCC患者癌组织及癌旁组织中hTERTmRNA和MDRmRNA的表达情况。
3.Objective To investigate the effect of telomerase activity and hTERT mRNA expression in SMMC7721 cells treated with GDCA in vitro.目的探讨甘氨脱氧胆酸钠(glycodeoxycholic acid,GDCA)对肝癌SMMC7721细胞端粒酶活性以及hTERTmRNA表达影响。
3)telomere-telomerase端粒-端粒酶
4)Telomerase[te'l?m?reis]端粒酶
1.Preparation and Telomerase Inhibition of Cationic Porphyrins Bearing Quinolyl and Mixed Quinolyl/pyridyl Meso Groups;喹啉或喹啉/吡啶混合取代阳离子型卟啉化合物的制备和端粒酶抑制活性研究(英文)
2.Effect of telomerase antisense nucleotide and cisplatin on gastric cancer cell;端粒酶反义寡核苷酸及其联合顺铂对胃癌细胞的影响
3.Value of combined pleural effusion testing of telomerase and CEA for differential diagnosis of malignant and nonmalignant pleural effusion;联合检测端粒酶和癌胚抗原对良恶性胸腔积液的诊断价值的研究
5)telomerase activity端粒酶
1.Altered telomerase activity during chemoprevention of experimental hamster cheek pouch carcinogenesis by Gynostempa Pentaphyllum Mak.;绞股蓝总甙对金地鼠颊囊白斑癌变过程中端粒酶活性化学预防作用研究
2.Changes and clinical significances of erythrocyte immune function,tumor supplied group of factors and telomerase activity in leukemia;白血病患者红细胞免疫功能、恶性肿瘤相关物质群和端粒酶活性变化及意义
3.Determination of telomerase activity in BALF in the diagnosis of lung cancer;支气管肺泡灌洗液端粒酶活性检测与肺癌的诊断
6)hTERT端粒酶
1.Analysis on Proteomic Profiling of Human Bone Marrow Mesenchymal Stem Cells Transduced with hTERT Gene;转人端粒酶基因骨髓间充质干细胞的蛋白表达谱分析
2.Expression of Survivin Bax and hTERT in Cutaneous Malignant Melanoma and the Relationship Between Them;皮肤恶性黑素瘤凋亡相关基因Survivin Bax表达及其与端粒酶的关系
3.Experimental study of hTERT activating telomerase in human odontoblast;hTERT激活人成牙本质细胞端粒酶的实验研究
延伸阅读
端粒酶分子式：CAS号：性质：一种以逆转录的方式合成真核细胞中线性染色体端粒DNA的特殊酶。该酶的辅基为一特定的RNA，端粒DNA的合成必须依赖酶分子中的辅基RNA为模板，通过逆转录而完成，其自身携带RNA作为产物的模板是区别于一般由纯蛋白组成的逆转录DNA聚合酶的主要特征。在逆转录时需要一个DNA引物，以便从5′→3′方向添加端粒的重复序列。底物是脱氧核苷三磷酸(dNTPs)。如在四膜虫(tetraphymena)中，四膜虫端粒酶催化反应式如下：染色体-GGGGTTGGGGTT(DNA引物)+4ndGTP(dNTPs)+2nTTP(dNTPs)→染色体-GGGGTTGGGGTT(GGGGTT)n(四膜虫端粒DNA)+6n焦磷酸端粒酶的活性在胚系细胞、癌化细胞中活跃；在体细胞，尤其经多次分裂后的体细胞，其活性降低。该酶的活性也可能是多细胞器官限制其细胞增殖的一种机制之一。
