ERCC1切除修复交叉互补基因1
1.Objective: To study the relation between expression of excision repair cross- complementing gene 1 (ERCC1) in tissue of non-small cell lung cancer and long-term effect of platinum-based chemotherapy.目的:研究探讨非小细胞肺癌(non-small cell lung cancer,NSCLC)组织中DNA切除修复交叉互补基因1(excision repair cross-complementing 1,ERCC1)的表达与铂类化疗远期疗效之间的关系,并观察该指标及相关临床因素对患者预后的影响。
2.A number of nucleic acid repair genes such as excision repair cross-complementing gene 1(ERCC1) and human xeroderma pigmentosum gene D(XPD/ERCC2),the level descent may be susceptible factors to one or certain kinds of tumors;but if these genes′ level are higher,the ability to repair damage and chemotherapy-induced genetic damage will be enhanced,it may be resistance to chemotherapeutic drugs.一些核酸修复基因,如切除修复交叉互补基因1(ERCC1)及人类着色性干皮病基因D(XPD/ERCC2)的水平下降,可能会成为某种或某几种肿瘤的易感因素;但如果此种基因的水平较高,修复损伤的能力提高,对化疗药物所致基因损伤的修复能力也就增强了,那么可能对化疗药物产生耐药现象。
3)ERCC1核苷酸切除修复交叉互补基因-1
1.Expression of ERCC1 in colorectal cancer and its clinical significance;核苷酸切除修复交叉互补基因-1在结直肠癌中的表达及其意义
4)excision repair cross-complementation group 1/ genetics切除修复交叉互补基因1/遗传学
5)excision repair cross-complementing 1(ERCC1)核苷酸切除修复交叉互补基因1(ERCC1)
6)excision repair cross completion gene 1切除修复交叉互补基因1(ERCC1)
延伸阅读
切除1.用外科手术把身体上受伤或病变的部分切掉。
