DNA拓扑异构酶类,DNA topoisomerases
1)DNA topoisomerasesDNA拓扑异构酶类
2)TopoisomeraseⅡDNA拓扑异构酶Ⅱ
1.Objective To examine the expression of Glutathione-s-transferase-π(GST-π),TopoisomeraseⅡ(TopoⅡ),Estrogen receptor(ER),Progesterone receptor(PR) in breast carcinoma tissues and study on clinical relationship between GST-π,TopoⅡ,ER and PR in breast carcinoma.目的检测谷胱甘肽-S-转移酶-π(GST-π)、DNA拓扑异构酶Ⅱ(TopoⅡ)及雌、孕激素受体(ER、PR)在乳腺癌组织中的表达,分析其在乳腺癌临床病理特征间的关系。
2.[Objective]To study clinical significance of topoisomeraseⅡ(TopoⅡ),proliferating cell nuclear antigen(PCNA) expression in gastric mucosal of chronic atrophic gastritis(CAG) patients.目的观察慢性萎缩性胃炎(CAG)患者胃黏膜标本中DNA拓扑异构酶Ⅱ(ToPoⅡ)和增殖细胞核抗原(PCNA)的表达及意义。
英文短句/例句

1.Development of DNA Topoisomerase Ⅱ inhibitorsDNA拓扑异构酶Ⅱ抑制剂研究进展
2.Prognostic significance of topoisomerase II alpha in patients with glioma;DNA拓扑异构酶Ⅱalpha在脑胶质瘤中的表达及与预后的相关性研究
3.The category, characteristic of DNA topoisomerases and research progress of inhibitorDNA拓扑异构酶Ⅰ和Ⅱ的结构特性及抑制剂的研究进展
4.Antitumor activity of compound Mirabijalone B and its effect on DNA topoisomerasesMirabijalone-B的抗肿瘤效应及对DNA拓扑异构酶的影响
5.The Antitumor Compounds Targeted on DNA Topoisomerases Screening;基于DNA拓扑异构酶的抗肿瘤活性物质的靶向筛选
6.Emodin inhibited ATP binding to Topoisomerase II to induce DNA double-strand breaks大黄素通过抑制ATP与拓扑异构酶II的结合导致DNA产生双链断裂
7.Screening of inhibitors of recombinant human DNA topoisomerase Ⅰ from mangrove endophytic fungi从红树林内生真菌筛选重组人DNA拓扑异构酶Ⅰ抑制剂的研究
8.The Screening of DNA Topoismerase Inhibitor and Inhibiting DNA Topoismerase Mechanisms and Antineoplasmic Activity of Two Chemical Compounds;DNA拓扑异构酶抑制剂的筛选及两种化合物的酶活抑制机制、抗肿瘤活性研究
9.Downregulation the expression of Top Ⅰ gene can improve sensitivity of Top Ⅰ inhibitors in small cell lung cancer cell lines下调DNA拓扑异构酶Ⅰ基因提高小细胞肺癌细胞株对足叶乙甙的敏感性
10.TopoisomeraseⅢWas Involved in the Eradication of Hypernegatively Supercoiled pBR322 in E.coli topA Mutants在拓扑异构酶Ⅰ缺失的大肠杆菌中拓扑异构酶Ⅲ参与高负超螺旋的消除(英文)
11.Expression of topoisomerase Ⅱα in breast cancer neoadjuvant chemotherapy patients乳腺癌新辅助化疗对拓扑异构酶Ⅱα表达的影响
12.Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain昆嵛山拓扑异构酶抑制剂原料植物资源调查
13.The Experimental Research and Clinical Observation on the Treatment of Refractory/relapse Acute Myeloid Leukemia with Topoisomerase Ⅰ Inhibitors Topotecan;拓扑异构酶Ⅰ抑制剂拓扑替康治疗难治/复发性急性髓系白血病的基础与临床研究
14.Probing DNA-damage-pathway by a Couple of DNA Intercalators;利用DNA拓扑结构探针研究DNA损伤信号转导
15.The effect of EB virus bhrfl gene expressing on the topoisomerase Ⅰ expression in nasopharyngeal carci noma cell lineEpstein-Barr病毒bhrfl表达对鼻咽癌细胞株CNE2拓扑异构酶Ⅰ表达的影响
16.Objective:To investigate the correlation between Topo Ⅱα expression and chemosensitivity in epithelial ovarian carcinoma (EOC).目的 :研究卵巢癌拓扑异构酶Ⅱα表达与化疗敏感性的关系。
17.Expression of Topo Ⅱα and Ki-67 in Human Hepatocellular Carcinoma and Its Significance;拓扑异构酶Ⅱα与Ki-67在肝细胞癌中的表达及意义
18.The Antitumor Activity of Albaconol and Its Effect on DNA Topoisomerase Activity and Angiogenesis Activity in Vitro;Albaconol的抗肿瘤活性及对拓扑异构酶活性和血管生成的影响
相关短句/例句

TopoisomeraseⅡDNA拓扑异构酶Ⅱ
1.Objective To examine the expression of Glutathione-s-transferase-π(GST-π),TopoisomeraseⅡ(TopoⅡ),Estrogen receptor(ER),Progesterone receptor(PR) in breast carcinoma tissues and study on clinical relationship between GST-π,TopoⅡ,ER and PR in breast carcinoma.目的检测谷胱甘肽-S-转移酶-π(GST-π)、DNA拓扑异构酶Ⅱ(TopoⅡ)及雌、孕激素受体(ER、PR)在乳腺癌组织中的表达,分析其在乳腺癌临床病理特征间的关系。
2.[Objective]To study clinical significance of topoisomeraseⅡ(TopoⅡ),proliferating cell nuclear antigen(PCNA) expression in gastric mucosal of chronic atrophic gastritis(CAG) patients.目的观察慢性萎缩性胃炎(CAG)患者胃黏膜标本中DNA拓扑异构酶Ⅱ(ToPoⅡ)和增殖细胞核抗原(PCNA)的表达及意义。
3)DNA topoisomeraseDNA拓扑异构酶
1.DNA topoisomerase and antitumor;DNA拓扑异构酶与抗肿瘤
2.The antitumor activity of a vanadium compound LMC in inhibiting DNA topoisomerase;一种钒配合物LMC抑制DNA拓扑异构酶Ⅰ的抗肿瘤作用
3.Expression of DNA topoisomerase Ⅱ in proliferative cells;DNA拓扑异构酶Ⅱ在增殖细胞中的表达及其意义
4)DNA topoisomerases-ⅡDNA拓扑异构酶-Ⅱ
5)DNA topoisomerase ⅡDNA拓扑异构酶Ⅱ
1.Expression and Significance of DNA Topoisomerase Ⅱin Esophageal Carcinoma;DNA拓扑异构酶Ⅱ在食管癌的表达及意义
2.Expression of P-glycoprotein, DNA topoisomerase Ⅱ, glutathione S-transferase π in malignant digestive canal carcinomas;消化道恶性肿瘤组织中P糖蛋白、DNA拓扑异构酶Ⅱ及谷胱甘肽转移酶π亚型的表达
3.Objective:To evaluate the clinicopathological significance of expressions of c-erbB-2,p53,proliferating cell nuclear antigen(PCNA),DNA topoisomerase Ⅱ(TopoⅡ),estrogen receptor(ER) and progesterone receptor(PR) in breast cancer.目的:探讨c-erbB-2、p53、增殖细胞核抗原(proliferating cell nuc lear antigen,PCNA)和DNA拓扑异构酶Ⅱ(DNAtopoisom eraseⅡ,TopoⅡ)及雌激素受体(estrogen receptor,ER)和孕激素受体(progesterone receptor,PR)在乳腺癌的表达和临床病理关系。
6)DNA topoisomeraseDNA拓扑异构酶Ⅱ
1.Objective To investigate the relationship between the expression of glutathione-s-transferase-π (GST-π),P-glycoprotein (P-gp) and DNA topoisomerase (Topo Ⅱ) and pathological characteristics and prognosis and multi-drug resistance in colorectal cancer.目的探讨大肠癌组织中谷胱甘肽S转移酶(GST-π)、糖蛋白(P-gp)和DNA拓扑异构酶Ⅱ(TopoⅡ)的表达与临床病理和预后及多药耐药的关系。
延伸阅读

DNA拓扑异构酶分子式:CAS号:性质:在DNA复制期间和子DNA分子分离时催化DNA链瞬间时断裂的一种酶。