杂合缺失,loss of heterozygosity英语短句,例句大全

杂合缺失,loss of heterozygosity
1)loss of heterozygosity杂合缺失
1.Loss of heterozygosity of chromosome 22 in sporadic colorectal carcinoma;散发性结直肠癌22号染色体等位基因杂合缺失
2.Methods: Mutation in exon 3 of β-catenin gene and mutation cluster region of APC gene, loss of heterozygosity and methylation status of promoter 1A of APC gene in breast cancer and normal tissue around tumor were detected by polymerase chain reaction-single strand conformation polymorphism, microsatellite analysis and methylation specific PCR.方法:应用PCR-SSCP、微卫星标记、甲基化特异性PCR方法检测乳腺癌和癌旁正常乳腺组织中β-catenin基因外显子3和APC基因突变密集区突变、APC基因杂合缺失(LOH)和启动子1A区甲基化状态,用RT-PCR检测APC基因mRNA表达;并用免疫组织化学法检测APC和β-catenin蛋白表达。
3.Objective Loss of heterozygosity (LOH) of tumor suppressor gene(TSG) is believed to play a key role in carcinogenesis of colorectal cancer (CRC).目的抑癌基因的杂合缺失(LOH)被认为是结直肠癌形成的通路之一,本实验拟通过对染色体10q23～24区的LOH分析,发现高频杂合缺失区域并筛查与结直肠癌相关的抑癌基因。

英文短句/例句

1.An Analysis of HCCS1 Gene Mutation and Loss of Hetrozygosity in Hepatocellular Carcinoma肝细胞癌HCCS1基因突变和杂合缺失分析
2.Loss of heterozygosity at different chromosomes in pa-tients with breast cancer.乳腺癌病人不同染色体位点上杂合缺失的研究
3.Refined Deletion Mapping of Loss of Heterozygosity in Sporadic Colorectal Cancer;散发性结直肠癌等位基因杂合缺失的精细定位研究
4.Refinement of High Heterozygosity Loss on Chromosome in Sporadic Colorectal Cancer;散发性结直肠癌高频杂合缺失精细定位及SMAD4基因突变的初步研究
5.Experimental Study of Loss of Heterozygosity and Imprinting of CDKN1C on Laryngeal Squamous Cell Carcinoma;喉鳞状细胞癌中CDKN1C基因杂合性缺失和印记缺失的实验研究
6.The Relationship between the Loss of Heterozygosity and Loss of Expression of p57~(kip2) mRNA人肝癌p57~(kip2)基因表达缺失与杂合性缺失的关系研究
7.Heterozygote deficiency coefficients (F) of the two populations in Daya Bay and Beibu Gulf were -0.278 and -0.346,respectively;两个种群的杂合子缺失系数分别为-0.278和-0.346;
8.Loss of Heterozygosity and Protein Expression of p73 Gene in Breast Cancer;乳腺癌p73基因杂合性缺失及其蛋白表达的研究
9.Loss of Heterozygosity of p16 Gene and Expression of hMSH2 mRNA in Gastric Cancer;胃癌组织p16基因杂合性缺失与hMSH2 mRNA的表达
10.Loss of Heterozygosity Analysis at 6q16-q23 in Pathogenesis of Non-Hodgkin Lymphomas;6q16-q23杂合性缺失与NHL发病相关性的初步研究
11.Investigation of the Loss of the Heterozygosity to nm23-H_1 Gene and Its Association with the Biocharicteristics of Lung Cancer;nm23-H_1基因杂合性缺失与肺癌生物学特性
12.Loss of Hetrozygosity in Esophageal Squamous Cell Carcinoma and Precursor Lesion;食管癌及癌前病变基因杂合性缺失的研究
13.Study on the correlation between the loss of microsatellite heterozygosity and thyroid carcinoma微卫星杂合性缺失与甲状腺癌相关性研究
14.Detection and Significance of Loss of Heterozygosity on 8p22 in Chronic Myeloid Leukemia慢性粒细胞白血病8p22杂合性缺失的检测及意义
15.Research of Loss of Heterozygaity on Chromosome 3P in Non-small Cell Lung Cancer;非小细胞肺癌3P基因多区域杂合性缺失联合检测的研究
16.On Present Essay s Iconic Deficiency From the Perspective of Lu Xun s Essay;从鲁迅杂文看当下杂文形象性的缺失
17.Significance of loss of heterozygosity chromosome 1 in hepatocellular carcinoma肝癌1号染色体等位基因杂合性缺失及临床意义
18.Expression, Mutation and LOH of Gene ING1 in Sporadic Colorectal Carcinoma;散发性结直肠癌中ING1基因的表达、突变及杂合性缺失研究

相关短句/例句

LOH杂合缺失
1.Detection of allele-specific chromosome 3p25 by PCR -LOH in 35 cases of esophageal carcinoma;食管癌患者3p25等位基因杂合缺失的初步研究
2.Methods: We performed restriction fragment length polymorphism (RFLP) analysis by using the polymerase chain reaction (PCR) and primer sets of two DNA markers to examine loss of heterozygosity (LOH) from 3p in glioma samples.方法 :应用 PCR技术配合限制性片段长度多态性 (RFL P)分析 ,对胶质瘤 3号染色体短臂3p2 4两个 DNA标志不同位点的杂合缺失 (L OH)进行检测。
3)loss of heterozygosity杂合性缺失
1.Identification of some macrosatillite sites of chromosome 19 in primary gastric carcinoma with loss of heterozygosity;19号染色体微卫星杂合性缺失与原发性胃癌的临床关系
2.Analysis of loss of heterozygosity in tk gene of L5178Y mouse lymphoma cells induced by colchicine and vincristine;秋水仙碱和长春新碱诱导L5178Y小鼠淋巴瘤细胞tk基因杂合性缺失分析
3.Study of loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma;胃癌FHIT基因杂合性缺失及微卫星不稳定性的研究
4)LOH杂合性缺失
1.Study on 10q23 LOH and Both Mutation and Expression of PTEN Gene of the Oesophageal Squamous Cell Carcinomas in Chinese Population;中国人食管癌10q23杂合性缺失和PTEN基因突变及表达研究
2.Methods PCR-denaturing polyacrylamide gel electrophoresis-silver staining method was used to detect LOH of three mic- rusatellite locus located in the WWOX gene site of 31 breast cancer tissues.目的检测乳腺癌组织中WWOX基因的杂合性缺失(LOH)状况及WWOX蛋白的表达状况,并探讨其与乳腺癌临床病理参数之间的关系。
3.Objective:To detect the loss of heterozygosity(LOH) of ING1 gene microsatellite and the expression of p33ING1b protein in lung carcinoma and to investigate their association with the carcinogenesis of lung cancer.目的:检测肺癌中抑癌基因ING1微卫星杂合性缺失(LOH)及其主要蛋白产物p33ING1b的表达情况,以探讨ING1基因改变与肺癌发生发展的关系。
5)loss of heterozygosity杂合子缺失
6)Loss of hererozygosity杂合型缺失