端粒酶催化亚单位,hTERT
1)hTERT端粒酶催化亚单位
1.Construction of Tumor Cells Specific Expression Vector of Suicide Gene of HSV-TK Driven by hTERT Promotor;人端粒酶催化亚单位启动子调控自杀基因HSV-TK肿瘤细胞特异性表达载体的构建
2.Expression of Human Telomerase Catalytic Subunit(hTERT) and Human Telomerase Associated Protein(TP1) in Bone Tumors;人端粒酶催化亚单位及其相关蛋白在骨肿瘤中的表达
3.Objective To explore the diagnostic value of telomerase activity (TA) and hTERT expression in pleural effusions.目的 探讨胸腔积液中端粒酶活性 (TA)与端粒酶催化亚单位 (hTERT)在胸腔积液诊断中的价值。
英文短句/例句

1.Expression of Human Telomerase Reverse Transcriptase and c-myc in Osteosarcoma;端粒酶催化亚单位和c-myc在骨肉瘤中的表达
2.Induction of Anti-tumor Immunity Using a Dendritic Cell-targeting Adenovirus Encoding Telomerase Reverse Transcriptase;端粒酶催化亚单位重组腺病毒疫苗的抗肿瘤作用的实验研究
3.Expression of Telomerase Reverse Transcriptase and Its Relationship with Expression of c-myc in Laryngeal Squamous Cell Carcinomas;端粒酶催化亚单位与c-myc在喉鳞癌组织中的表达及意义
4.Expression and Regulation of Telomerase Reverse Transcriptase (hTERT) in Human Lymphocytes From Normal Individuals;不同年龄正常人外周血淋巴细胞端粒酶催化亚单位的表达及调控
5.Correlation of hTERT single nucleotide polymorphism with susceptibility to esophageal carcinoma端粒酶催化亚单位Ex2-659A/G多态性与食管癌易感性的研究
6.Study on pharmacokinetics and acute toxicity of human telomerase reverse transcriptase antisense oligonucleotide molecular probe人端粒酶催化亚单位反义分子探针的药代动力学与急性毒性研究
7.An Experimental Study of hTERT Promoter on Targeting Therapy for Lung Cancer with Suicide Gene HSV-TK;人端粒酶催化亚单位启动子调控自杀基因HSV-TK靶向性表达治疗肺癌的实验研究
8.Uptake kinetics of hTERT antisense molecular probe by cells and its biological properities人端粒酶催化亚单位(hTERT)反义分子探针细胞摄取动力学与生物学性质
9.Study on the Diagnostic Value of Telomerase Activity and hTERT in Pleural Effusions;胸腔积液端粒酶活性和催化亚单位检测的诊断价值研究
10.Mechanisms and Biological Significances of the Regulation of hTERT Nucleolar Localization;端粒酶催化亚基核仁定位的调控机制及其生物学意义研究
11.Effect of siRNA Targeting the Subunit of Telomerase on Hepatocellular Carcinoma;端粒酶亚单位的siRNA对肝癌的作用
12.Influence on SGC-7901 Cell Proliferation and Telomerase Activity by Stably RNAi hTERT and TRAP Gene;稳定干扰端粒酶催化亚基及转录因子对SGC-7901细胞增殖和端粒酶活性的影响
13.Clone and sequence analysis of telomerase reverse transcriptase gene from Giardia canis犬贾第虫端粒酶催化亚基基因的克隆及序列分析
14.Therapeutic Effects of Antisense-hTERTcDNA on Ovarian Cancer Mediated by Retroviral Vector in Vivo;病毒载体介导端粒酶催化亚基反义基因治疗卵巢癌的研究
15.The Effect of ELE on Telomerase Activity and Telomerase Catalytic Subunit hTERT in Hela Cell;榄香烯对Hela细胞端粒酶活性及对hTERT催化亚基的影响
16.Treatment of Endometrial Cancer Cells in Vitro and in Vivo with Antisense Oligodeoxynucleotides of Human Telomerase Reverse Transcriptase Gene;人端粒酶催化亚基反义寡核酸抑制子宫内膜癌的实验研究
17.Study of Telomerase Activity and Its Subunits in Brain Gliomas;脑胶质瘤端粒酶活性表达及其亚单位基因表达的研究
18.Study of Telomerase Activity and Its Subunits in Cervical Cancer;宫颈癌端粒酶活性表达及其亚单位基因表达的研究
相关短句/例句

telomerase catalytic subunit端粒酶催化亚单位
1.Effect of elemene emulsion on gene expression of telomerase catalytic subunit in HeLa cell;榄香烯对HeLa细胞端粒酶催化亚单位基因表达的作用
3)Human telomerase reverse transcriptase端粒酶催化亚单位
4)human telomerase reverse transcriptase mRNA人端粒酶催化亚单位mRNA
5)hTERT人端粒酶催化亚单位
1.Hammerhead ribozyme against human telomerase catalytic subunit (hTERT) induced apoptosis of liver cancer cells;人端粒酶催化亚单位锤头状核酶诱导肝癌细胞凋亡的作用
2.Objective To clone sequence of hTERT promoter and study its transcriptional activity and its relationship with hTERT mRNA expression and telomerase activity in various kinds of human lung cancer cells and normal cells,and to investigate the targeting transcriptional activity of hTERT promoter in tumor cells.目的克隆人端粒酶催化亚单位(hTERT)启动子序列片段,并探讨hTERT启动子在肿瘤细胞中的靶向转录活性。
3.Objective To investigate the effect of human telomerase reverse transcriptase(hTERT) in the(immortalization) of human neural stem cells(NSCs).目的明确外源性人端粒酶催化亚单位(hTERT)在人神经干细胞永生化过程中的作用。
6)hTERT端粒酶催化亚单位蛋白
1.Expression and Significance of hTERT and PCNA Protein in Condyloma Acuminata;端粒酶催化亚单位蛋白及PCNA在尖锐湿疣组织中的表达及意义
延伸阅读

端粒酶分子式:CAS号:性质:一种以逆转录的方式合成真核细胞中线性染色体端粒DNA的特殊酶。该酶的辅基为一特定的RNA,端粒DNA的合成必须依赖酶分子中的辅基RNA为模板,通过逆转录而完成,其自身携带RNA作为产物的模板是区别于一般由纯蛋白组成的逆转录DNA聚合酶的主要特征。在逆转录时需要一个DNA引物,以便从5′→3′方向添加端粒的重复序列。底物是脱氧核苷三磷酸(dNTPs)。如在四膜虫(tetraphymena)中,四膜虫端粒酶催化反应式如下:染色体-GGGGTTGGGGTT(DNA引物)+4ndGTP(dNTPs)+2nTTP(dNTPs)→染色体-GGGGTTGGGGTT(GGGGTT)n(四膜虫端粒DNA)+6n焦磷酸端粒酶的活性在胚系细胞、癌化细胞中活跃;在体细胞,尤其经多次分裂后的体细胞,其活性降低。该酶的活性也可能是多细胞器官限制其细胞增殖的一种机制之一。