1)platelet derived growth factor BB血小板衍生生长因子BB
1.Objective To investigate the relationship between the expression of platelet derived growth factor BB(PDGF-BB)、vascular endothelial growth factor C(VEGF-C)and the clinicopathologic parameters in colonic carcinoma,and to explore the difference of VEGF-C and PDGF-BB expression in primary tumor and metastatic lymph node.目的探讨结肠癌组织中血小板衍生生长因子BB(PDGF-BB)、血管内皮生长因子C(VEGF-C)的表达,及其与肿瘤临床病理参数之间的关系;分析在结肠原发癌与相应淋巴结转移癌中VEGF-C、PDGF-BB表达是否存在差异。
2.Significance of platelet derived growth factor BB on the development of cerebral vasospasm;目的 探讨血小板衍生生长因子BB(PDGF BB)在蛛网膜下腔出血 (SAH)后的表达及其对正常脑血管的影响 。
2)platelet-derived growth factor BB血小板衍生生长因子BB
1.Objective:To explore the relationship among vascular endothelial growth factor C(VEGF-C),platelet-derived growth factor BB(PDGF-BB),lymphangiogenesis and lymph node metastasis in human non-small cell lung cancer(NSCLC).目的:探讨血管内皮生长因子C(VEGF-C)和血小板衍生生长因子BB(PDGF-BB)在非小细胞肺癌(NSCLC)中的表达与淋巴管生成和淋巴结转移的关系。
2.Objective To investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB(PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.目的 研究血小板衍生生长因子BB(PDGF-BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
3)platelet derived growth factor-BB血小板衍生生长因子-BB
1.Objective To explore the effects of platelet derived growth factor-BB(PDGF-BB)and basic fibroblast growth factor(bFGF)on alkaline phosphatase(ALP)activity in human periodontal ligament cells(hPDLCs)in vitro.目的探讨血小板衍生生长因子-BB(PDGF-BB)和碱性成纤维细胞生长因子(bFGF)对人牙周膜(PDL)细胞碱性磷酸酶(ALPase)活性的影响。
英文短句/例句
1.Development of A Procedure for Expression of Human Platelet-Derived Growth Factor-BB in Saccharomyces cerevisiae and Purification of Expressed Product人血小板衍生生长因子-BB在酿酒酵母中的表达及纯化工艺的建立
2.platelet derived growth factor血小板衍生生长因子
3.Effects of platelet-derived growth factor-BB and basic fibroblast growth factor on the proliferation of human periodontal ligament cells血小板衍化生长因子-BB和碱性成纤维细胞生长因子对人牙周膜细胞增殖的影响
4.Relationship between Serum Platelet Derived Growth Factor-BB and IgA Nephropathy in ChildrenIgA肾病患儿血清血小板源性生长因子-BB与临床病理的关系
5.Expression and Significance of Platelet-derived Growth Factor-BB in Patients with Hepatic Diseases血小板源性生长因子BB在肝病患者中的表达及意义
6.Expression of platelet-derived growth factor-BB in patients with lung cancer血小板源性生长因子-BB在肺癌患者中的表达及意义
7.Role of Platelet-Derived Growth Factor-BB in Lymphangiogenesis and Lymph Node Metastasis of Human Breast Cancer血小板源性生长因子-BB在人类乳腺癌淋巴管生成及淋巴结转移中作用
8.An Experimental Study of Biological Effects of Platelet-Derived Growth Factor on Vascular Histiocytes;血小板衍化生长因子对血管组织细胞生物学作用的实验研究
9.Effect of Abciximab on PDGF and Injured Tunica Intima of Common Carotid Artery of Rabbit;Abciximab对兔颈总动脉内膜损伤及血清血小板衍生生长因子的影响
10.Expression of TGF-β,bFGF and PDGF in fracture healing转化生长因子-β、碱性成纤维生长因子和血小板衍生生长因子在大鼠骨折愈合中的表达
11.Molecular Clone and Expression of Human Plateletderived Growth Factor B Chain Mature Peptide Gene;人血小板衍生生长因子B链成熟肽基因克隆及表达
12.Objective: To determine the amino acid composition and isoelectric point of porcine platelet-derived growth factor.目的:测定猪血小板衍生生长因子的氨基酸组成和等电点。
13.An Experimental Study of Biological Effects of Platelet-Derived Growth Factor on Brain Injury;外伤性脑损伤后血小板衍化生长因子的生物学作用实验研究
14.Role of Platelet-Derived Growth Factor (PDGF)-AA in the Balance of Bone Turnover;血小板衍生生长因子AA在骨代谢转换平衡中的作用
15.Expression of PDGF-A, PDGF-B in Hilar Cholangiocarcinoma;血小板衍生生长因子A和B在肝门部胆管癌中的表达
16.Expression of Thymidine Phosphorylase/platelet-derived Endothelial Cell Growth Factor in Gastric Carcinoma and Precancerous Lesions;血小板衍生内皮细胞生长因子在胃癌和胃癌癌前病变中的表达
17.Relationship between PDGF-BB/PDGFR-β and the Early Stage of Liver Fibrosis in Experimental Diabetic Tree Shrews;血小板衍生生长因子及其受体与糖尿病树鼩早期肝纤维化的关系
18.The Expression and Significance of PDGFR in Laryngeal Squamous Cell Carcinoma;血小板衍生生长因子受体在喉鳞状细胞癌中的表达及意义
相关短句/例句
platelet-derived growth factor BB血小板衍生生长因子BB
1.Objective:To explore the relationship among vascular endothelial growth factor C(VEGF-C),platelet-derived growth factor BB(PDGF-BB),lymphangiogenesis and lymph node metastasis in human non-small cell lung cancer(NSCLC).目的:探讨血管内皮生长因子C(VEGF-C)和血小板衍生生长因子BB(PDGF-BB)在非小细胞肺癌(NSCLC)中的表达与淋巴管生成和淋巴结转移的关系。
2.Objective To investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB(PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.目的 研究血小板衍生生长因子BB(PDGF-BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
3)platelet derived growth factor-BB血小板衍生生长因子-BB
1.Objective To explore the effects of platelet derived growth factor-BB(PDGF-BB)and basic fibroblast growth factor(bFGF)on alkaline phosphatase(ALP)activity in human periodontal ligament cells(hPDLCs)in vitro.目的探讨血小板衍生生长因子-BB(PDGF-BB)和碱性成纤维细胞生长因子(bFGF)对人牙周膜(PDL)细胞碱性磷酸酶(ALPase)活性的影响。
4)Platelet-derived growth factor-BB血小板衍生生长因子-BB
1.MethodsHepatic stellate cells (HSCs) isolated from rats were primarily cultured in uncoated plastic culture dish for 7 days, then were incubated with 10~ -6 mmol/L SA-B and stimulated with 10 ng/ml transforming growth factor-β_1 (TGF-β_1) or platelet-derived growth factor-BB (PDGF-BB).方法分离大鼠肝星状细胞(HSC),于无包被塑料培养皿中原代培养7天,继以10-6mmol/L SA-B孵育,再加10ng/ml的转化生长因子β1(TGF-β1)或血小板衍生生长因子-BB(PDGF-BB)刺激。
5)PDGF-BB血小板衍生生长因子-BB
1.Objectives:To investigate the inhibitory effect of Danshengsu on proliferation、collagen typeⅠsynthesis and Phosphorylated extracellular signal- regulated kinase 1/2 (P-ERK1/2)expression of rat hepatic stellate cell ( HSC ) stimulated by platelet derived growth factor-BB (PDGF-BB),and to elucidate the molecular mechanism of Danshensu against hepatic fibrosis.目的观察丹参素对血小板衍生生长因子-BB (platelet derived growth factor-BB PDGF-BB)刺激大鼠肝星状细胞(hepatic stellate cell HSC )增殖、Ⅰ型胶原合成、磷酸化细胞外信号调节激酶1/2(Phosphorylated extracellular signal- regulated kinase 1/2 ,P-ERK1/2)表达的影响,探讨丹参素抗肝纤维化的分子机制。
2.Real-time fluorescence quantitative PCR method was used to determine the effects of Qingfei oral liquid medicated serumon on the expression of TGF-β_1 and PDGF-BB mRNA genes.观察清肺口服液含药血清对RSV感染后人胚肺成纤维细胞转化生长因子-β_1和血小板衍生生长因子-BB mRNA基因表达的影响。
6)PDGF-BB血小板衍化生长因子-BB
1.Objective To study the effect of interferon on TGFβ_1,MMP-1,PDGF-BB and ppGalNAc-T_2 in fibroblast of pathological scars and the mechanism of interferon on pathological scars.目的在体外研究干扰素2b(INF-α2b)对瘢痕组织成纤维细胞转化生长因子-β1(TGF-β1)、基质金属蛋白酶-1(MMP-1)、血小板衍化生长因子-BB(PDGF-BB)以及糖基转移酶(ppGalNAc-T2)基因表达的作用,以求阐明干扰素对增生性瘢痕的作用机理。
延伸阅读
血小板衍生生长因子分子式:CAS号:性质:platelet derired growth factor;PDGF 贮存于血小板α颗粒中的一种碱性蛋白质,是一些细胞,如纤维母细胞、平滑肌细胞、神经胶质细胞的促细胞分裂剂。包括PDGF-I和PDGF-II,二者所含蛋白质相同,仅糖苷含量各异,它们是由两个不同的多肽链由二硫键结合而成的二聚体,其中A链较大(PDGF-I中的A链为17 000,PDGF-II中的A链为15 000),B链较小(14 000)。由血小板纯化得到的PDGF为AB、BB双聚体,许多肿瘤细胞中的PDGF为AA双聚体。目前认为PDGF在伤口愈合、胆固醇与磷酯合成的调节、动脉粥样硬化等多种生理及病理过程中起重要作用。
