1)p21 WAF1 genep21WAF1基因
2)p21WAF1/CIP1 genep21WAF1/CIP1基因
1.Effect of transfected p21WAF1/CIP1 gene on bioactivity of human gastric cancer cells;目的探讨p21WAF1/CIP1基因(p21基因)对人胃癌细胞系(BGC)生物学活性的影响。
3)p21 WAF1/CIP1 genep21WAF1/CIP1基因
4)p21 WAF1p21wAF1
1.Objective To investigate the effects of histone acetylation on the expression of p53 and p21 WAF1 genes in malignant transformation of IEC-6.方法采用我们已建立的3个转化期(化学致癌剂MNNG和诱导剂PMA共同作用6、12、24次)的IEC-6转化细胞进行培养,提取不同转化时期的IEC-6转化细胞的细胞核蛋白,采用免疫印迹检测H3乙酰化水平;并用ChIP及RT-PCR检测组蛋白H3乙酰化对p21WAF1表达的影响。
2.Objective:To investigate the association between Cyclin D1 and metastasis and determine the relationship between Cyclin D1 proteins expression and P21 WAF1?P53 proteins in ovarian cancer.目的:探讨细胞周期蛋白(CyclinD1)表达与卵巢癌转移的相关性和CyclinD1与P21WAF1、P53蛋白的关系。
3.Objective:To investigate the biological features of breast carcinoma and analyze P53,P21 WAF1 and Cyclin E s functions in the genesis,progression and metastasis of breast carcinoma by the examination of P73,P21 WAF1 and Cyclin E,and their relationship with clinical-pathological feature indexes.目的:通过检测P53蛋白、P21WAF1蛋白、CyclinE在乳腺癌中的表达及其与临床病理指标的关系,探讨乳腺癌的生物学特性,分析它们在乳腺癌的发生、转移中所起的作用。
5)P21~(WAF1)P21WAF1
1.Objective: To characterize the alterations of P21~(WAF1) in concurrent cancers of the esophagus and gastric cardia(CC) from the same patient.目的:探讨同一个体食管贲门双源癌组织P21WAF1蛋白变化特征及其意义。
2.Objective To explore the expression and clinical significance of p21~(WAF1) and CDk4 in breast cancer tissue.目的探讨乳腺癌组织中p21WAF1及CDK4的表达及临床意义。
3.Objective To investigate theeffect of cigarette smoke extract on theproliferation of alveolar epithelial cells type Ⅱ and its relationship with the expression of P21~(WAF1).目的探讨香烟烟雾提取物(cigarette smoke extract,CSE)对人类肺泡Ⅱ型上皮细胞来源的A549细胞增殖的影响及其与P21WAF1表达的关系。
6)p21 WAF1/CIP1p21WAF1/CIP1
1.Objective:In order to evaluate the significance of the expression of p21 WAF1/CIP1 and PCNA (proliferating cell nuclear antigen) in hypopharyngeal and laryngeal squamous cell carcinoma.目的:探讨p21WAF1/CIP1和抑制增殖细胞核抗原(PCNA)的表达与下咽癌、喉癌的分级、转移及预后 的关系,了解p21WAF1/CIP1在下咽癌、喉癌发生、发展中的作用以及与PCNA的相关性。
2.Objective To verify the binding of p53to p21 WAF1/CIP1 gene promoter and detect its binding to hsp90βgene promoter in vivo.目的验证抑癌基因表达产物p53蛋白在体内是否结合于p21WAF1/CIP1基因的启动子区,并检测p53蛋白对热休克蛋白hsp90β基因启动子区的结合情况。
3.Resver atrolalso significantly improved the expression of P21 WAF1/CIP1 mRNA and protein.目的:探讨白藜芦醇(Resvratrol,Res)在体外对肝癌细胞分化及相关周期蛋白依赖激酶抑制因子P21WAF1/CIP1的影响。
英文短句/例句
1.THE SIGNIFICANCE OF EXPRESSION OF MDM2,P53 AND P21～WAF1/CIP1 IN GASTRIC CARCINOMAS;MDM2、p53和p21WAF1/CIP1蛋白在胃癌中的表达及意义
2.Expression and Clinical Significance of PTEN and P21～(waf1) in Nasopharyngeal Carcinoma;抑癌基因PTEN、P21waf1在鼻咽癌中的表达及其临床意义
3.IKKβ Overexpression is Correlated with p21～(CIP1/WAF1) Expression in Breast Cancers;乳腺癌中IKKβ与p21～（CIP1/WAF1）的相关性研究
4.Effect of p21～(WAF1/CIP1) on Prostate Cancer Cell Growth;p21～（WAF1/CIP1）对前列腺癌细胞增殖的影响
5.The Study of Apoptosis Induced by p21～(WAF/CIPP1) Gene Transfection into Renal Carcinoma Cells;转染p21～（WAF1/CIP1）基因对肾癌细胞促凋亡作用的研究
6.Expressions of p21～(WAF1/CIP1) and p27～(KIP1) in Hepatocellular Carcinoma;肝细胞肝癌中p21～(WAF1/CIP1)和p27～(KIP1)蛋白表达的研究
7.Expression of p21~(WAF1/CIP1) and TGF-β1 in Retinoblastoma and Its Significancep21~（WAF1/CIP1）、TGF-β1在视网膜母细胞瘤中的表达及意义
8.The expression of p21~(WAF1/CIP1) protein in adult mouse follicle and corpus luteump21~(WAF1/CIP1)蛋白在小鼠卵泡与黄体中的表达
9.Expression of p21~(WAF1/CIP1) in retinoblastoma and its significancep21~(WAF1/CIP1)在视网膜母细胞瘤中的表达及意义
10.Regulatingrole of p21~(WAF1/CIP1) promoter by selenium on breast cancer cell硒对乳腺癌细胞株p21~(WAF1/CIP1)启动子的调控作用
11.An Experimental Study of the Effect of WAF1/CIP1 on the Growth and Apoptosis of the Cell of Esophageal Carcinoma;P21～（WAF1/CIP1）对食管癌细胞生长及凋亡作用的实验研究
12.Silencing Cellular P21~(WAF1/CIP1) by Small Interfering RNA Inhibits Herpes Simplex Virus Type Ⅱ Propagation下调细胞P21~(WAF1/CIP1)基因表达可抑制单纯疱疹病毒Ⅱ型复制
13.Effects of Resveratrol on the Differentiation of Human Liver Carcinoma Cell line HepG2 and the Expression of P21~(WAF1/CIP1)白藜芦醇体外对肝癌HepG2细胞分化及P21~(WAF1/CIP1)表达的影响
14.Influences of recombinant decorin gene transfection on p21~(WAF1/CIP1) of HepG2 hepatoma cells重组核心蛋白聚糖转染对HepG2细胞p21~(WAF1/CIP1)表达的影响
相关短句/例句
p21WAF1/CIP1 genep21WAF1/CIP1基因
1.Effect of transfected p21WAF1/CIP1 gene on bioactivity of human gastric cancer cells;目的探讨p21WAF1/CIP1基因(p21基因)对人胃癌细胞系(BGC)生物学活性的影响。
3)p21 WAF1/CIP1 genep21WAF1/CIP1基因
4)p21 WAF1p21wAF1
1.Objective To investigate the effects of histone acetylation on the expression of p53 and p21 WAF1 genes in malignant transformation of IEC-6.方法采用我们已建立的3个转化期(化学致癌剂MNNG和诱导剂PMA共同作用6、12、24次)的IEC-6转化细胞进行培养,提取不同转化时期的IEC-6转化细胞的细胞核蛋白,采用免疫印迹检测H3乙酰化水平;并用ChIP及RT-PCR检测组蛋白H3乙酰化对p21WAF1表达的影响。
2.Objective:To investigate the association between Cyclin D1 and metastasis and determine the relationship between Cyclin D1 proteins expression and P21 WAF1?P53 proteins in ovarian cancer.目的:探讨细胞周期蛋白(CyclinD1)表达与卵巢癌转移的相关性和CyclinD1与P21WAF1、P53蛋白的关系。
3.Objective:To investigate the biological features of breast carcinoma and analyze P53,P21 WAF1 and Cyclin E s functions in the genesis,progression and metastasis of breast carcinoma by the examination of P73,P21 WAF1 and Cyclin E,and their relationship with clinical-pathological feature indexes.目的:通过检测P53蛋白、P21WAF1蛋白、CyclinE在乳腺癌中的表达及其与临床病理指标的关系,探讨乳腺癌的生物学特性,分析它们在乳腺癌的发生、转移中所起的作用。
5)P21~(WAF1)P21WAF1
1.Objective: To characterize the alterations of P21~(WAF1) in concurrent cancers of the esophagus and gastric cardia(CC) from the same patient.目的:探讨同一个体食管贲门双源癌组织P21WAF1蛋白变化特征及其意义。
2.Objective To explore the expression and clinical significance of p21~(WAF1) and CDk4 in breast cancer tissue.目的探讨乳腺癌组织中p21WAF1及CDK4的表达及临床意义。
3.Objective To investigate theeffect of cigarette smoke extract on theproliferation of alveolar epithelial cells type Ⅱ and its relationship with the expression of P21~(WAF1).目的探讨香烟烟雾提取物(cigarette smoke extract,CSE)对人类肺泡Ⅱ型上皮细胞来源的A549细胞增殖的影响及其与P21WAF1表达的关系。
6)p21 WAF1/CIP1p21WAF1/CIP1
1.Objective:In order to evaluate the significance of the expression of p21 WAF1/CIP1 and PCNA (proliferating cell nuclear antigen) in hypopharyngeal and laryngeal squamous cell carcinoma.目的:探讨p21WAF1/CIP1和抑制增殖细胞核抗原(PCNA)的表达与下咽癌、喉癌的分级、转移及预后 的关系,了解p21WAF1/CIP1在下咽癌、喉癌发生、发展中的作用以及与PCNA的相关性。
2.Objective To verify the binding of p53to p21 WAF1/CIP1 gene promoter and detect its binding to hsp90βgene promoter in vivo.目的验证抑癌基因表达产物p53蛋白在体内是否结合于p21WAF1/CIP1基因的启动子区,并检测p53蛋白对热休克蛋白hsp90β基因启动子区的结合情况。
3.Resver atrolalso significantly improved the expression of P21 WAF1/CIP1 mRNA and protein.目的:探讨白藜芦醇(Resvratrol,Res)在体外对肝癌细胞分化及相关周期蛋白依赖激酶抑制因子P21WAF1/CIP1的影响。
延伸阅读
1,4,9(11),16-Pregnatetraene-21-ol-3,20-dione-21-acetate分子式：暂无分子量：暂无CAS号：暂无性质：暂无制备方法：暂无用途：激素类药。
