1)multidrug resistance-associated protein 2多药耐药相关蛋白2
1.AIM:To develop a high-performance liquid chromatography internal standard method for determining of cefditoren in the rat plasma,bile and urine,and to clarify the relation between multidrug resistance-associated protein 2(Mrp2)and biliary excretion of cefditoren using perfused rat livers.目的:建立高效液相色谱内标法测定大鼠血浆、胆汁、尿液中头孢妥仑含量,阐明多药耐药相关蛋白2(Mrp2)是否与头孢妥仑胆汁排泄有关。
2.Objective:To detect expression of heme oxygenase(HO-1)and multidrug resistance-associated protein 2(MRP2),and investigate its significance in primary gallbladder carcinoma.目的:检测血红素加氧酶-1(heme oxygenase,HO-1)与多药耐药相关蛋白2(multidrug resistance-associated protein2,MRP2)在原发性胆囊癌组织中的表达,探讨其与胆囊癌发生、发展的关系。
英文短句/例句
1.Reversal Effect of Delavirdine on MRP2-mediated Multidrug Resistance地拉夫定对多药耐药相关蛋白2介导的多药耐药逆转研究
2.Relationship between expression of multidrug resistant associated protein 2,multidrug resistant associated protein 3 and clinical pathological features in esophageal squamous cell carcinoma多药耐药相关蛋白2、3的表达与食管鳞癌临床病理特征的关系
3.Multidrug Resistance-Associated Protein Gene Mediated Drug Resistance in Acute Leukemias;急性白血病多药耐药相关蛋白基因介导的多药耐药研究
4.Reversal effect of Schisandrin A on MRP1-mediated multidrug resistance五味子甲素逆转多药耐药相关蛋白1多药耐药机制的研究
5.Advances of the Correlation between the LRP and MDR of Tumor肺耐药相关蛋白与肿瘤多药耐药相关性的研究进展
6.Effect of hypoxia on expression of MRP1 and the mechanism in human EC9706 cell line乏氧对EC9706细胞多药耐药相关蛋白表达的影响
7.Overexpression of MRP1 Is Associated with Acquired Tolerance To Arsenic In L-02 Cell多药耐药相关蛋白1与人肝细胞耐砷性关系的研究
8.Proteomic Analysis of Multidrug Resistance Related Proteins in Chronic Myelogenous Leukemia Cell Lines and Study on the Mechanism of MDR;慢性粒细胞白血病急变细胞株多药耐药相关蛋白的蛋白质组学分析及耐药机制研究
9.P-glycoprotein in Rheumatoid Arthritis and Multidrug Resistance-related ResearchP-糖蛋白与类风湿关节炎多药耐药的相关性研究
10.Chemotherapy Sensitization to THP-1 Cells and Relationship with Multidrug Resistance Associated Protein-1 Treated by Cyclosporin A环孢素A对THP-1细胞的增敏作用及与多药耐药相关蛋白-1的关系
11.The Correlation Study of PKC-α and MDR in Kidney Cancer;蛋白激酶C-α（PKC-α）在肾癌中与多药耐药相关性研究
12.Study of PKC Enzymatic Activity in Multidrug Resistance of Human Renal Cell Carcinoma;蛋白激酶C（PKC）与肾细胞癌多药耐药相关性的研究
13.Effect of cyclosporin A on expression of multidrug resistance associatedprotein-1 in THP-1 cells环孢素A对THP-1细胞多药耐药相关蛋白-1表达的影响
14.EXPRESSION AND FUNCTIONAL SIGNIFICANCE OF MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN IN PANCREATIC ADENOCARCINOMA CELL多药耐药相关蛋白MRP在胰腺癌细胞中的表达及意义
15.The Relationship of Drug Resistance Associated Protein, Mismatch Repair Protein Expression to Drug Resistance in Gastrointestinal Carcinoma;消化道癌耐药性产生与耐药相关蛋白、错配修复蛋白表达的关系
16.Structure-functional Relationship of Candida Albicans Multidrug Resistance Protein;白念珠菌多药耐药蛋白Cdr1p构效关系研究
17.Study of Expression and Their Relationship of COX-2 and P-gp in Osteosarcoma;骨肉瘤组织中环氧合酶-2和P-耐药糖蛋白的表达及其相关性研究
18.Expression of Lung-resistance Protein,Epidermal Growth Factor Receptor and HER-2 in Breast Infiltrating Duct Cancer and Its Clinical Significance肺耐药蛋白在乳腺浸润性导管癌中的表达及与EGFR、HER-2的相关性
相关短句/例句
Multidrug resistance-associated protein 2(MRP2)多药耐药相关蛋白-2
3)Multidrug resistance-associated protein多耐药相关蛋白
1.Objective To investigate the relationship between membrane protein MRP3 (multidrug resistance-associated protein 3) and nuclear receptor Lrh-1 (liver receptor homologue-1) in bile duct ligated (BDL) rat liver.目的通过建立梗阻性黄疸动物模型,在蛋白水平观察多耐药相关蛋白MRP3(multidrug resistance-associated protein3,MRP3)和核受体Lrh-1(liver receptor homologue-1)表达变化并分析二者之间的关系。
4)multi-drug related protein-2 (MRP-2)多药耐药相关蛋白-2(MRP-2)
5)Multidrug resistance-associated proteins多药耐药相关蛋白类
6)MRP多药耐药相关蛋白
1.Effect of Arsenic Tioxide on MRP Expression in A549/R Cell Line of Human Lung Cancer;三氧化二砷对人肺腺癌A549/R细胞多药耐药相关蛋白表达的影响
2.Recently,researches are focussed on the MDR,including P-glycoprotein(Pgp),multidrug resistance-associated protein(MRP),lung resistance-asspcoated protein(LRP),topoisomerase II(TopoII)and breast cancer resistance protein(BCRP).目前,P-糖蛋白(P-glycoprotein,Pgp)、多药耐药相关蛋白(multidrug resistance-associated protein,MRP)、肺耐药相关蛋白(lung re-sistance-associated protein,LRP)、拓扑异构酶II(topoisomeraseII,TopoII)及乳腺癌耐药蛋白(breast cancer resist-ance protein,BCRP),已成为人们研究的热点。
3.Objective To investigate the expression of glucose transporter1(GLUT1),multidrug resistance related protein(MRP) and glutathione S-transferase pi(GST-π)in lung cancer.目的探讨肺癌组织中糖转运蛋白1(glucose transporter1,GLUT1)、多药耐药相关蛋白(multi-drug resistance related protein,MRP)和谷胱甘肽S转移酶-π(glutathione S-transferasepi,GST-π)的表达及其相关性。
延伸阅读
安眠药、镇静药安眠药、镇静药HyPnoties，Sedatives an而anyao、Zhenjingyao安眠药、镇静药Hypnotics，SedativeS蔡月刚上海医药工业研究院L概述··············……2.主要的安眠、镇静药2.1.醇类·········.··..……2.2.环状酞胺类·····……2.3.酸脉类···········……2.4.氨基甲酸醋类·”一2.5.苯二氮草类····……2.6.吩唯嗦类·······································……312.7.乙醇胺类·······································……312.8.二苯甲烷类······················，····……，··……312.9.叱咯酮类·······································……312.10.巴比妥类·······································……31参考文献················································……咒墓本参考文献··········································……33q八成J gJ广n占亡户nt了0‘2，﹄Q乙2，︺21.概述 安眠药又称催眠药，是一类对中枢神经系统产生抑制作用的药物，在应用适当剂量时，这种抑制作用能导致睡眠(见神经调节荆)。在较小剂量时可使紧张、焦虑和兴奋不安的患者安静下来，有思睡状态，但又不致入睡，这时就称为镇静药。大剂量的安眠药还可产生麻醉。实际上安眠药和镇静药并无明显的界限，而只有量的差别。有些类别的安眠药如使用特大剂量时还可引起昏迷和可能死亡。 失眠是一种不能得到良好睡眠的生理现象，表现为入睡困难、早醒、夜不成寐，即使暂时入睡，但醒后常感头晕脑胀、腰酸背痛，并无正常睡眠醒后的清新之感等等，总之，失眠患者常不能从睡眠中完全消除疲劳。失眠常与下列原因有关;如焦虑、心理障碍、精神上的打击、噪声(见噪声)和工作过度等等。长期失眠可造成中枢神经细胞功能失调，适当应用安眠药是必要的。 理想的安眠药应能使病人安然入睡，而在醒后不遗留任何不适感，并有正常工作的能力。一般患有失眠症的人，服用安眠药后即能获得类似生理性的睡眠，但多数醒后有精神萎靡不振等不良反应。如由于某些躯体疾病，如关节炎、神经痛和心绞痛等引起的失眠，则需首先进行病因性治疗口长期应用安眠药可产生依赖性和成瘾性。 目前对于睡眠发生的机理尚不清楚，但经过多年的努力，已经深入了一步。
