1)Hereditary colorectal cancer遗传性大肠癌
英文短句/例句
1.To Analysis Pathogenic Relation Gene of Hereditary Colorectal Cancer Establishment and Management of a Tissure Bank in Yunnan Province云南省遗传性大肠癌相关致病基因的分析及标本库的建立与管理
2.Clinical Analysis and Molecular Genetic Study of Hereditary Nonpolyposis Colorectal Cancer Kindreds;遗传性非息肉病性大肠癌（HNPCC）家系研究
3.Gene Diagnosis of Hereditary Nonpolyposis Colorectal Cancer and Preliminary Construction of Its Mutation Database;遗传性非息肉病性大肠癌基因诊断及其基因突变库的初步构建
4.Clinicopathologic characteristics,diagnosis,and treatment of 30 patients with hereditary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌30例临床病理特点与诊治分析
5.The analysis of clinicopathological feature and prognosis of hereditary non-polyposis colorectal cancer遗传性非息肉病性大肠癌临床病理特点和预后分析
6.Expressions of MMP-7、TIMP-2 and their correlation to the biological behaviours of hereditary nonpolyposis colorectal cancerMMP-7和TIMP-2表达在遗传性非息肉病性大肠癌侵袭转移中的作用
7.Analyze of Clinical Phenotype of the Hereditary Nonpolyposis Colorectal Cancer in Northerner of China and Basic Research of Its Molecular Genetics;中国北方人遗传性非息肉病性大肠癌临床表型分析及其分子遗传学基础研究
8.The Significant of Fas/FasL Protein Expression and the Quantity of TIL in Hereditary Nonpolyposis Colorectal Cancer;遗传性非息肉病性大肠癌癌组织中Fas/FasL蛋白的表达及TIL计数的意义
9.Molecular and Clinical Pathology Features of Hereditary Non-Polyposis Colorectal Cancer (HNPCC);遗传性非息肉病性结直肠癌的分子遗传及临床病理研究
10.Analysis of the Phenotype Features and Their Molecular Mechanism of Hereditary Nonpolyposis Colorectal Cance (HNPCC);遗传性非息肉病性结直肠癌表型分析及分子遗传基础研究
11.This disease has familial transmissibility more, it is the pathology base with rectum main cancer.该病多有家族遗传性，是直肠癌重要的病理基础。
12.Genetic Polymorphisms of DNA Repair Genes and P53 Pathway Genes and Risk of Colorectal Cancer in Chinese Population;结直肠癌遗传易感性的分子流行病学研究
13.The Study of Lymphatic Metastasis and nm23H_1 Gene Heredity Instability of Colon Cancer;结肠癌淋巴转移和nm23H_1基因遗传不稳定性的研究
14.One Family Report of Fulfilling Chinese HNPCC Criteria;符合中国人遗传性非息肉病性大肠癌家系标准的一家系报告附文献综述
15.Clinicopathological Significance of DNA Methylation and Its Relationship with Genetic Mechanism in Sporadic Colorectal Cancer;散发性大肠癌DNA甲基化的临床病理意义及其和遗传学机制的关系研究
16.Association between survivin promoter -31C/G polymorphism and genetic susceptibility to sporadic colorectal cancersurvivin基因启动子区-31C/G多态性与散发性结直肠癌遗传易感性的关系
17.Study of Screening Hereditary Nonpolyposis Colorectal Cancer Families Based on mRNA Sequencing;基于胚系mRNA异常筛选遗传性非息肉病性结直肠癌家系的研究
18.An Study of Methylation of Mismatch Repair Gene in Hereditary Nonpolyposis Colorectal Cancer;遗传性非息肉病性结直肠癌中错配修复基因甲基化的研究
相关短句/例句
hereditary non-polyposis colorectal cancer遗传性非息肉性大肠癌
3)Hereditary non-polyposis colorectal cancer遗传性非息肉病性大肠癌
1.Hereditary non-polyposis colorectal cancer (HNPCC),also called Lynch syndrome,is an autosomal-dominantly inherited disease and is associated with germline mutations in mismatch repair(MMR)genes and microsatellite instability(MSI).遗传性非息肉病性大肠癌(HNPCC)是一种由错配修复基因(MMR)突变造成的常染色体显性遗传病,又称Lynch综合征,是遗传性大肠癌的代表。
2.Objective To investigate the relationship between microsatellite instability(MSI) and the expression of transforming growth factor β receptor II(TGFβRII),mismatch repaire(MMR) proteins in Hereditary Non-polyposis Colorectal Cancer(HNPCC).目的观察遗传性非息肉病性大肠癌(HNPCC)和大肠腺瘤癌组织中TGFβRII、错配修复基因(hMLH1、hMSH2、hMSH6)蛋白表达和微卫星不稳定(MSI)的关系。
4)Hereditary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌
1.Clinical characteristic,diagnosis and therapy of hereditary nonpolyposis colorectal cancer in 32 cases of 11 families;遗传性非息肉病性大肠癌11个家系32例的临床特点与诊治
2.Background and ObjectivesHereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal and dominantly inherited cancer predisposition caused by a constitutional defect in a mismatch repair (MMR) gene, with a disease penetrance that approaches 80-90%.研究背景与目的 遗传性非息肉病性大肠癌(HNPCC)是由于DNA错配修复基因(MMR)发生胚系突变所致的一种单基因显性遗传性疾病,占所有结直肠癌的5%-15%,外显率达80%-90%,多见于青年患者(年龄≤40岁)。
5)herediary nonpolyposis colorectal cancer遗传性非息肉病性大肠癌(HNPCC)
6)hereditary nonpolyposis colorectal cancer(HNPCC)遗传性非息肉病性大肠癌/HNPCC
延伸阅读
大肠癌 位于大肠的常见恶性肿瘤。大多发生于40岁以上,男性患者约为女性的两倍。根据肿瘤发生的部位,可分为直肠癌和结肠癌。前者早期无明显症状,或大便带血,以后逐渐出现大便频、黏液便、便血、里急后重等症状。晚期因肠腔狭窄,大便外形变细或扁平。后者主要表现为腹痛,先呈间歇性隐痛,后为持续性疼痛、绞痛,便溏,带脓血,便次增多。晚期肠癌均可见消瘦,乏力,并可扪及腹中包块。根据临床表现结合直肠指诊、X线检查、癌胚抗原检查、结肠镜检或取活组织作病理检查,可予确诊。中医古代无大肠癌病名。 大肠癌病因尚不明确。一般认为,可能与直肠和结肠内慢性炎症刺激有关。中医学认为,此病多因忧思郁怒,或饮食不节导致气机不畅、运化失常,以至瘀血湿浊积聚而成。 肠癌的早、中期以根治手术治疗为主,术后配合中医药治疗以巩固疗效。晚期无手术指征的患者,以中医药治疗为主,配合化疗或姑息性放疗。中医辨证治疗根据患者的不同临床表现一般分为湿热瘀毒、气滞血瘀、脾肾寒湿、肝肾阴虚、气血两虚等证型辨证论治。①湿热瘀毒。证见腹痛腹胀,大便次数增多,夹带黏液脓血,或里急后重,或便溏便细,得矢气则胀减,腹有包块,舌黯红,或有瘀斑,苔黄,脉弦数。治宜清热利湿、解毒消积。方用白头翁汤合地榆槐角汤加减。②气滞血瘀。证见腹部刺痛,包块坚硬不移,腹胀,腹泻,里急后重,泻出紫黑脓血,舌紫黯或有瘀斑,苔黄,脉涩。治宜理气化滞、活血化瘀。方用膈下逐瘀汤加减。③脾肾寒湿。证见久泻久痢,形体消瘦,面色苍白,肠鸣腹泻,腹中绵绵作痛,喜按喜温,恶寒肢冷,或大便失禁,污浊频出,舌淡,苔白,脉沉细无力。治宜健脾温中,方用附子理中汤合补中益气汤加减。④肝肾阴虚。证见五心烦热,形体瘦削,头晕目眩,潮热盗汗,口渴咽干,大便不爽或燥结,少腹包块,腹痛便血,舌红或黯红,少苔或光剥,脉弦细而数。治宜滋补肝肾、清热解毒,方用知柏地黄汤合大补阴丸加减。⑤气血两虚。证见形体消瘦,神疲气短,头晕心悸,双目昏暗,纳差少食,大便溏薄,舌淡苔白或少苔,脉细弱。治宜补气养血,方用八珍汤加味。 大肠癌多在辨证论治的基础上配合使用专方专药。常用的专方有上海的大肠癌方、消癌丸、山甲苦参汤、清肠消肿汤、肠癌饼、肠癌灌肠剂等。常用于肠癌的中草药有半枝莲、喜树根、鸦胆子、败酱草、白花蛇舌草、红藤、蚤休、肿节风、石榴皮、蛇莓、儿茶、大黄、大蒜、地榆、白头翁、蟾蜍、地鳖虫、守宫等。
