pithelial-mesenchymal transition (EMT)上皮间质转化(EMT)
3)epithelial-mesenchymal transition上皮细胞间质转化态
1.Objective: To determine the characteristics of epithelial-mesenchymal transition(EMT) in different human prostate cancer cell lines and explore the molecular mechanisms of bone metastatic potentials.目的:对多种转移潜能不同的人前列腺癌细胞“上皮细胞间质转化态”(EMT)特性进行鉴定,并从粘附因素和细胞骨架蛋白角度分析其骨转移潜能获得的分子机制。
2.Objective:To determine whether human prostate cancer cell lines undergo epithelial-mesenchymal transition(EMT) and become more invasive when induced by HIF-1α,and to explore the underlying molecular mechanism.目的:研究人前列腺癌细胞在缺氧诱导因子1α(HIF-1α)诱导下能否发生上皮细胞间质转化态(EMT)改变,进而致侵袭能力增强,并初步分析其分子机制。
3.Conclusion: E-cadherin and β-catenin are differently expressed and distributed in prostate cancer cell lines with different characteristics of epithelial-mesenchymal transition(EMT),and the abnormal activation of the β-catenin signal pathway may be involved in the EMT of prostate cancer cells.结论:不同上皮细胞间质转化态(EMT)特性的前列腺癌细胞系中E-cadherin/β-catenin表达以及分布存在差异,β-catenin的核转位可能是诱发前列腺癌细胞系发生EMT改变的机制之一。
4)Epithelial-mesen-chymal transdifferentiation细胞上皮间质样转化
5)mesenchymal to epithelial transition间质-上皮细胞的转化
6)Epithelial-Mesenchymal transit (EMT)上皮-间质细胞转变
延伸阅读
睾丸支持细胞-间质细胞瘤睾丸支持细胞-间质细胞瘤 又称“男性母细胞瘤”、“睾丸腺瘤”。由幼稚睾丸基质所发生的肿瘤。小儿有性早熟现象，肿大的睾丸有肿块。尿17-酮类固醇、促性腺激素及雌激素皆正常，但孕二醇及促黄体激素增高。肿瘤限于睾丸内，瘤质均匀，黄色。瘤细胞大小不等，呈圆形或不规则，排列成片状、索状或乳头状。手术治疗，预后良好。
