基因拷贝数改变,DNA copy number alteration
1)DNA copy number alteration基因拷贝数改变
1.【Background and Purpose】DNA copy number alterations play an important role in the initiation and progression of pancreatic ductal adenocarcinoma(PDAC).【材料与方法】收集2007年6月至2008年12月PDAC患者手术切除肿瘤组织标本15例,利用显微切割技术,富集肿瘤细胞,提取基因组DNA,通过array CGH分析,鉴定PDAC的基因拷贝数改变
英文短句/例句

1.Detection of DNA Copy Number Alterations in Pancreatic Ductal Adenocarcinoma胰腺导管腺癌基因拷贝数改变的研究
2.A Study on DNA Copy Number Alterations Related to Metastasis in Lung Squamous Cell Carcinomas肺鳞癌转移相关基因组DNA拷贝数改变的研究
3.Copy-number variation:a new pattern of structural diversity in genome拷贝数变异:基因组多样性的新形式
4.Genome-wide Copy Number Variation Study Associated with Obesity in Chinese Population中国人群肥胖与全基因组拷贝数变异关联研究
5.SNP and CN ariation correlated with altered actiity in almost 900 and 240 genes, respectiely.单核苷酸多态性与变异基因拷贝数分别与近900和240个基因的活性改变有关。
6.Detection of Copy-Transform-Move Forgery in Color Digital Image数字彩色图像拷贝-变换-移动篡改检测
7.FcgRIIIb Gene Copy Number Polymorphism Predisposes to Susceptibility of IgAN in Chinese;IgA肾病与Fcgr3B基因拷贝数多态性研究
8.Association between Copy Number Variants within Metabotropic Glutamate Receptors 7 Gene and Schizophrenia代谢型谷氨酸受体7基因的拷贝数变异与精神分裂症的相关性
9.Study on Mitochondrial DNA Mutations and Alteration of Copy Numbers in Breast Cancer;乳腺癌线粒体DNA突变和拷贝数改变的研究
10.Copy Number and Integration Site of Transgene in Transgenic Pig转基因猪中外源基因拷贝数和整合位点的研究
11.Association of FCGR3B Gene Relative Copy Number and 1upus Nephritis;FCGR3B基因相对拷贝数和狼疮肾炎的相关性研究
12.Study on Application of the Whole Genome Amplification in LCN;全基因组扩增法应用于低拷贝数DNA检测
13.Estimating copy number of transgenic gene by real-time fluorescent quantitative PCR(TaqMan)实时荧光定量PCR(TaqMan)法测定外源基因的拷贝数
14.Array-based comparative genomic hybridization detection of cryptic copy number variations in a fetus with de novo complex chromosome rearrangement微阵列比较基因组杂交检测复杂染色体重排胎儿隐藏的基因组拷贝数变化
15.Experimental study of whole genomic copy number variations in a fetus with a de novo isodicentric chromosome 18 by array-based comparative genomic hybridization微阵列比较基因组杂交分析18等臂双着丝粒染色体胎儿全基因组拷贝数变化
16.The Copy Number Detection of KIT Gene in Wuzhishan Pig and Association Analysis between Porcine PSME1 Gene and Immunity Traits;五指山猪KIT基因拷贝数检测暨猪PSME1基因与免疫性状关系的研究
17.Effect of Copy Numbers of Insect-Resistant Gene on Protein Expression and Inheritance in Trangegic Cotton;转基因抗虫棉抗虫基因拷贝数对蛋白表达及遗传的影响
18.Determination of Copy Number of Foreign Gene in Genome of Pichia pastoris by Real-time Fluorescent Quantitative PCR实时荧光定量PCR检测毕赤酵母基因组中外源基因拷贝数
相关短句/例句

copy number changes基因拷贝数变化
3)Gene copy number基因拷贝数
1.The effect of gene copy number and chromosomal position on heterologous gene expression in Saccharomyces cerevisae has been tentatively investigated using a modified hepatitis B virus surface antigen SA 28 gene.应用FLP重组酶介导的染色体定点整合技术,将带有不同拷贝数的乙肝病毒融合表面抗原SA28基因表达单元的质粒整合在酵母不同的染色体位点,并测定了SA28基因的表达情况,初步研究了基因拷贝数与染色体位置对酵母表达外源基因的影响。
2.A modified method for the estimation of gene copy number in genome is proposed.基因拷贝数分析的研究王瑛(中国科学院动物研究所,北京,100080)陈来同(北京大学生命科学学院,北京,100871)关键词基因拷贝数;单倍体基因组;α1-抗胰蛋白酶基因;大鼠RALRS-1重复序列中图分类号Q578基因拷贝数(copynumber)。
3.Methods Gene copy number per cell was investigated by fluorescence in situ hybridization(FISH) using the LSI EGFR SpectrumOrange/CEP 7 SpectrumGreen probe(Vysis,Abbott Laboratoriesm,IL) in nasopharyngeal carcinoma cells including CNE-1、CNE-2、HONE-1、 SUNE-1、HNE-1、HNE-2.目的检测鼻咽癌细胞系中表皮生长因子受体(EGFR)基因拷贝数扩增情况。
4)the transgenic copy number外源基因拷贝数
5)low copys低拷贝数基因
6)multi-copied gene多拷贝基因
延伸阅读

拷贝数分子式:CAS号:性质:(一)在细菌细胞中,某种特定质粒的数目。根据复制特性,质粒分严紧型和松弛型两类,前者在细胞中只含1~2个,而后者含10~15个以上。恒定的拷贝数与质粒复制控制系统、宿主细胞遗传背景及生长条件有关。质粒复制控制系统首先通过调节复制的起始点来控制拷贝数,调节因素包括阻遏蛋白、反义RNA和某些顺向重复序列。有些质粒还有其他控制系统,如有分配功能的par系统和确保质粒稳定遗传的ccd系统。一旦质粒上与调控有关的基因或位点突变,可使拷贝数明显增加或减少。(二)在细菌细胞中,某种特定基因的数目。