1)MDM2-p53 feedback loopMDM2-p53反馈环
1.Interfering with the MDM2-p53 feedback loop leads to p53 (wt) activation,ultimately preventing neoplasia.已有的研究显示，核糖体蛋白L23(RPL23)是细胞内调节MDM2-p53反馈环的一个重要分子。
英文短句/例句
1.Effects of MDM2-p53 Feedbackloop on the Chemotherapy Sensitivity of Ovarian Cancer Cell Lines to Cisplatin;MDM2-p53反馈环对卵巢癌细胞药敏性的影响及机制
2.feedback loop反馈回路,反馈环路
3.Effect of Qingdushuan on PTEN-MDM2-p53 Network of Cervical Cancer SiHa Cell清毒栓对宫颈癌SiHa细胞及PTEN-MDM2-p53网络环路的影响
4.single-loop feedback单(闭合)环路反馈
5.Experimental Study on the Radio-Sensitivity Enhancing Effects of an Artificial wt-p53 Positive Feedback Circuit Guided by Irradiation in Human Lung Adenocarcinoma;放射控导的野生型p53蛋白正反馈基因环路提高肺腺癌细胞对放射敏感性的实验研究
6.Study on Gastric Carcinoma and mdm2, p53 and p21 Gene Abnormality;胃癌与mdm2、p53及p21基因异常的研究
7.The Expression and Significance of p53, MDM2 and PCNA in Psoriasis;p53、MDM2和PCNA在银屑病中的表达及意义
8.The Relationship of p53, MDM2, p16, pRb expression with HPV Infection in Human Uterine Cervical Carcinoma;宫颈癌HPV感染与p53、MDM2、p16、pRb的关系
9.Expression and significance of MDM2 and p53 protein in lung adenocarcinomaMDM2、p53在肺腺癌中的表达及其意义
10.Expression of MDM2 and P53 in renal cell carcinomaP53、MDM2蛋白在肾细胞癌的表达及意义
11.Relationship between expressions of P53,MDM2 proteins and manganese induced apoptosis in PC12 cells锰诱导PC12细胞凋亡与P53、MDM2蛋白表达
12.The expression of p53,p27 and mdm2 in gastrointestional stromal tumorp53、p27及mdm2在胃肠道间质瘤中的表达
13.Studies of P53/MDM2/P21 and HBV Correlation in Hepatoma Cells;肝癌细胞中肿瘤基因P53/MDM2/P21与HBV关系的研究
14.The Expression of MDM2、PTEN和P53 Protein in Squamous Carcinoma of Uterine Cervix and Its Relationship;MDM2、PTEN与P53在宫颈鳞癌中的表达及其相关性研究
15.MDM2 and p53 Expression in Aqired Melanocytic Nevi and Epidermis;获得性黑素细胞痣及表皮中MDM2和p53蛋白的表达
16.Study of the Abnormality of p14～(ARF)-mdm2-p53 Pathway in Head and Neck Squamous Cell Carcinoma;头颈部鳞癌中p14～（FRF）-mdm2-p53途径异常的研究
17.A Study of Epstein-Barr Virus-Associated Gastric Carcinoma and mdm2, p53 and p21 Gene Abnormality;EBV相关胃癌与mdm2、p53及p21基因异常的研究
18.The Expression and Relatinship of PTEN, Mdm2 and p53 in Human Astrocytoma;星形细胞瘤中PTEN、Mdm2及p53表达的相关性研究
相关短句/例句
P53-MDM2 negative feedbackP53-MDM2负反馈
3)PTEN-MDM2-p53 networkPTEN-MDM2-p53网络
1.Objective To discuss the effect of Qingdushuan on SiHa cells of cervical cancer proliferation and protein expression in PTEN-MDM2-p53 network from the level of cell biology and molecular biology.目的从细胞生物学及分子生物学水平探讨清毒栓对宫颈癌SiHa细胞增殖抑制及对PTEN-MDM2-p53网络中各个蛋白表达的影响。
4)p53-MDM2 binding inhibitorp53-MDM2结合抑制剂
1.The pharmacophore model of p53-MDM2 binding inhibitors was established by the Catalyst software with the training set of 24 inhibitors containing 5 different kinds of structures.采用Catalyst软件,选择5类共24个p53-MDM2结合抑制剂作为训练集,经计算机建模、构象优化。
5)MDM2 p53 pathway regulationMDM2-p53通路调节
6)p53-Mdm2 interactionp53-Mdm2相互作用
延伸阅读
[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式：C16H16ClN3O3S分子量：365.5CAS号：26807-65-8性质：暂无制备方法：暂无用途：用于轻、中度原发性高血压。
