拓扑异构酶Ⅱ,topoisomerase Ⅱ英语短句,例句大全

拓扑异构酶Ⅱ,topoisomerase Ⅱ
1)topoisomerase Ⅱ拓扑异构酶Ⅱ
1.Anticancer drugs targeting DNA topoisomerase Ⅱ;以DNA拓扑异构酶Ⅱ为靶点的抗癌药物
2.The mRNA and protein level of topoisomerase Ⅱ(Topo Ⅱ) and transcript fa.方法用MTT法,测定H446小细胞肺癌细胞24 h抑制率;AO/EB双荧光染色观察细胞活率;琼脂糖凝胶电泳检测DNA断裂条带;半定量RT-PCR及蛋白印迹检测DNA拓扑异构酶Ⅱ(TopoⅡ)及特化蛋白1(SP1)的表达。
3.Objective To investigate the expression of lung resistance protein(LRP) and topoisomerase Ⅱ(TOPOⅡ) in stomach cancer and evaluate its clinical significance.目的探讨胃癌中肺耐药蛋白(LRP)、拓扑异构酶Ⅱ(TOPOⅡ)的表达及临床意义,以期为选择化疗方案提供参考,获得更有效的化疗效果。

英文短句/例句

1.Development of DNA Topoisomerase Ⅱ inhibitorsDNA拓扑异构酶Ⅱ抑制剂研究进展
2.Expression of topoisomerase Ⅱα in breast cancer neoadjuvant chemotherapy patients乳腺癌新辅助化疗对拓扑异构酶Ⅱα表达的影响
3.Objective:To investigate the correlation between Topo Ⅱα expression and chemosensitivity in epithelial ovarian carcinoma (EOC).目的 :研究卵巢癌拓扑异构酶Ⅱα表达与化疗敏感性的关系。
4.Expression of Topo Ⅱα and Ki-67 in Human Hepatocellular Carcinoma and Its Significance;拓扑异构酶Ⅱα与Ki-67在肝细胞癌中的表达及意义
5.Prognostic significance of topoisomerase II alpha in patients with glioma;DNA拓扑异构酶Ⅱalpha在脑胶质瘤中的表达及与预后的相关性研究
6.Expression and Association of HER-2/NEU and TopoⅡa in Human Ovary Epithelial Neoplasms;人表皮生长因子受体2和拓扑异构酶Ⅱa在卵巢上皮肿瘤的表达及意义
7.The category, characteristic of DNA topoisomerases and research progress of inhibitorDNA拓扑异构酶Ⅰ和Ⅱ的结构特性及抑制剂的研究进展
8.TopoisomeraseⅢWas Involved in the Eradication of Hypernegatively Supercoiled pBR322 in E.coli topA Mutants在拓扑异构酶Ⅰ缺失的大肠杆菌中拓扑异构酶Ⅲ参与高负超螺旋的消除(英文)
9.Antitumor activity of compound Mirabijalone B and its effect on DNA topoisomerasesMirabijalone-B的抗肿瘤效应及对DNA拓扑异构酶的影响
10.Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain昆嵛山拓扑异构酶抑制剂原料植物资源调查
11.The Experimental Research and Clinical Observation on the Treatment of Refractory/relapse Acute Myeloid Leukemia with Topoisomerase Ⅰ Inhibitors Topotecan;拓扑异构酶Ⅰ抑制剂拓扑替康治疗难治/复发性急性髓系白血病的基础与临床研究
12.The effect of EB virus bhrfl gene expressing on the topoisomerase Ⅰ expression in nasopharyngeal carci noma cell lineEpstein-Barr病毒bhrfl表达对鼻咽癌细胞株CNE2拓扑异构酶Ⅰ表达的影响
13.The Antitumor Compounds Targeted on DNA Topoisomerases Screening;基于DNA拓扑异构酶的抗肿瘤活性物质的靶向筛选
14.The Antitumor Activity of Albaconol and Its Effect on DNA Topoisomerase Activity and Angiogenesis Activity in Vitro;Albaconol的抗肿瘤活性及对拓扑异构酶活性和血管生成的影响
15.Study on the Mechanism for Topoisomerase Ⅱ Poison Teniposide Against Oral Cancer Cells;拓扑异构酶抑制剂替尼泊甙抗口腔癌机制的研究
16.Study of the Relationship between Topoismerase and the Prognostic, MDR of Ovarian Cancer;拓扑异构酶与卵巢癌预后及多药耐药关系的研究
17.Emodin inhibited ATP binding to Topoisomerase II to induce DNA double-strand breaks大黄素通过抑制ATP与拓扑异构酶II的结合导致DNA产生双链断裂
18.Screening of inhibitors of recombinant human DNA topoisomerase Ⅰ from mangrove endophytic fungi从红树林内生真菌筛选重组人DNA拓扑异构酶Ⅰ抑制剂的研究

相关短句/例句

TopoisomeraseⅡ拓扑异构酶Ⅱ
1.Background &Objective:Multi-drug resistance(MDR)is the most important failing reason of tumor chemotherapy,the substance that P-glycoprotein(P-gp),glutathione S-transferase-π(GST-π),TopoisomeraseⅡ(TopoⅡ)etc was the fundamental substances p roducing MDR.背景与目的:P糖蛋白(P-gp)、谷胱甘肽-S-转移酶(GST-π)和拓扑异构酶Ⅱ(Topo-Ⅱ)等多种细胞内物质是恶性肿瘤产生多药耐药的物质基础,胃癌是比较常见的恶性肿瘤,应用免疫组化方法检测化疗前P-gp、GST-π和Topo-Ⅱ三因素在胃癌中表达的报告还比较少,为此,本文检测P-糖蛋白(P-gp)、谷胱甘肽-S-转移酶(GST-π)和拓扑异构酶II(Topo-Ⅱ)在胃癌组织中的表达,探讨其与胃癌分化、转移的关系。
2.ObjectiveTo explore the expression and clinical significance of P-glycoprotein(P-gp), Glutathione-transferase pi(GST-π) and TopoisomeraseⅡ(TopoⅡ) in cervical cancer.目的:探讨P-糖蛋白(P-glycoprotein,P-gp)、谷胱甘肽S-转移酶-π(Glutathione-transferase pi,GST-π)和DNA拓扑异构酶Ⅱ(TopoisomeraseⅡ,TopoⅡ)在宫颈癌组织中的表达及其临床意义。
3.TopoisomeraseⅡ is an enzyme,important for DNA replication,transcription,mitosis and other vital process.在DNA复制,转录和有丝分裂等重要的生命过程中,拓扑异构酶Ⅱ是一种重要的酶。
3)TOPOⅡ拓扑异构酶Ⅱ
1.Objective To explore expression of multidrug resistance(MDR)gene production of Glycoprotein(p-gp),P-glutathione-s-transferase-π and TopoⅡ in breast cancer tissues.目的探讨多药耐药(MDR)基因产物P-糖蛋白(P-gp)、谷胱甘肽-S-转移酶-π(GST-π)及DNA拓扑异构酶Ⅱ(TopoⅡ)在乳腺癌组织中的表达,分析其与临床病理特征及预后的关系。
2.Objective:Observe the expressions of ER,PR,Cerb-B2,lung resistanceprotein(LRP), glutathione-S-transferase(GST-π),topoisomeraseⅡ(TopoⅡ),tumor suppressor gene product P53 protein in breast mucinous carcinoma and its clinical significance.目的:观察ER、PR、Cerb-B2、肺耐药蛋白(LRP)、谷胱甘肽-硫-转移酶π(GST-π)、拓扑异构酶Ⅱ(TopoⅡ)和肿瘤抑癌基因产物P53蛋白在乳腺粘液癌组织中的表达并探讨其临床意义。
3.Objective To explore the expression of multidrug resistance gene product LRP,GST-π and TopoⅡ in colorectal carcinoma tissue and evaluate its clinical significance.目的探讨大肠癌组织中多药耐药(MDR)基因产物肺耐药相关蛋白(LRP)、谷胱甘肽-S-转移酶π(GST-π)、拓扑异构酶Ⅱ(Topo Ⅱ)的表达及临床意义。
4)TopoisomeraseⅡDNA拓扑异构酶Ⅱ
1.Objective To examine the expression of Glutathione-s-transferase-π(GST-π),TopoisomeraseⅡ(TopoⅡ),Estrogen receptor(ER),Progesterone receptor(PR) in breast carcinoma tissues and study on clinical relationship between GST-π,TopoⅡ,ER and PR in breast carcinoma.目的检测谷胱甘肽-S-转移酶-π(GST-π)、DNA拓扑异构酶Ⅱ(TopoⅡ)及雌、孕激素受体(ER、PR)在乳腺癌组织中的表达,分析其在乳腺癌临床病理特征间的关系。
2.[Objective]To study clinical significance of topoisomeraseⅡ(TopoⅡ),proliferating cell nuclear antigen(PCNA) expression in gastric mucosal of chronic atrophic gastritis(CAG) patients.目的观察慢性萎缩性胃炎(CAG)患者胃黏膜标本中DNA拓扑异构酶Ⅱ(ToPoⅡ)和增殖细胞核抗原(PCNA)的表达及意义。
5)Topoisomerase-Ⅱ拓扑异构酶-Ⅱ
1.Objective:To investigate the expression of Topoisomerase-Ⅱ(Topo-Ⅱ)and explore its clinicopathological and prognostic significance in neuroblastoma.目的:探讨神经母细胞瘤中拓扑异构酶-Ⅱ(Topo-Ⅱ)表达的临床病理及预后意义。
6)DNA topoisomerases-ⅡDNA拓扑异构酶-Ⅱ