拓扑异构酶Ⅱα,Topoisomerase Ⅱα
1)Topoisomerase Ⅱα拓扑异构酶Ⅱα
1.Expression of Topoisomerase Ⅱα in Nasopharyngeal Carcinoma and Its Clinical Significance;鼻咽癌组织拓扑异构酶Ⅱα的表达及其临床意义
2.Objective To investigate the expression and clinical significance of Topoisomerase Ⅱαprotein in hepatocellular carcinoma(HCC) tissues and its relationship with p53 gene mutation.目的研究原发性肝癌拓扑异构酶Ⅱα(Topoisom eraseⅡ,αToPoⅡα)的表达及临床意义,并探讨其与p53基因突变之间的关系。
3.Objective To investigate the expression of topoisomerase Ⅱα (Topo Ⅱα) and its relationship with Ki67 protein, p53 gene in nonsmall cell lung carcinoma (NSCLC).目的 研究非小细胞肺癌患者拓扑异构酶Ⅱα (TopoisomeraseⅡα ,TopoⅡα)的表达 ,并探讨其与Ki6 7蛋白、p5 3基因的关系。
英文短句/例句

1.Expression of topoisomerase Ⅱα in breast cancer neoadjuvant chemotherapy patients乳腺癌新辅助化疗对拓扑异构酶Ⅱα表达的影响
2.Objective:To investigate the correlation between Topo Ⅱα expression and chemosensitivity in epithelial ovarian carcinoma (EOC).目的 :研究卵巢癌拓扑异构酶Ⅱα表达与化疗敏感性的关系。
3.Expression of Topo Ⅱα and Ki-67 in Human Hepatocellular Carcinoma and Its Significance;拓扑异构酶Ⅱα与Ki-67在肝细胞癌中的表达及意义
4.Development of DNA Topoisomerase Ⅱ inhibitorsDNA拓扑异构酶Ⅱ抑制剂研究进展
5.TopoisomeraseⅢWas Involved in the Eradication of Hypernegatively Supercoiled pBR322 in E.coli topA Mutants在拓扑异构酶Ⅰ缺失的大肠杆菌中拓扑异构酶Ⅲ参与高负超螺旋的消除(英文)
6.Antitumor activity of compound Mirabijalone B and its effect on DNA topoisomerasesMirabijalone-B的抗肿瘤效应及对DNA拓扑异构酶的影响
7.Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain昆嵛山拓扑异构酶抑制剂原料植物资源调查
8.The category, characteristic of DNA topoisomerases and research progress of inhibitorDNA拓扑异构酶Ⅰ和Ⅱ的结构特性及抑制剂的研究进展
9.The Experimental Research and Clinical Observation on the Treatment of Refractory/relapse Acute Myeloid Leukemia with Topoisomerase Ⅰ Inhibitors Topotecan;拓扑异构酶Ⅰ抑制剂拓扑替康治疗难治/复发性急性髓系白血病的基础与临床研究
10.The effect of EB virus bhrfl gene expressing on the topoisomerase Ⅰ expression in nasopharyngeal carci noma cell lineEpstein-Barr病毒bhrfl表达对鼻咽癌细胞株CNE2拓扑异构酶Ⅰ表达的影响
11.The Antitumor Compounds Targeted on DNA Topoisomerases Screening;基于DNA拓扑异构酶的抗肿瘤活性物质的靶向筛选
12.The Antitumor Activity of Albaconol and Its Effect on DNA Topoisomerase Activity and Angiogenesis Activity in Vitro;Albaconol的抗肿瘤活性及对拓扑异构酶活性和血管生成的影响
13.Study on the Mechanism for Topoisomerase Ⅱ Poison Teniposide Against Oral Cancer Cells;拓扑异构酶抑制剂替尼泊甙抗口腔癌机制的研究
14.Prognostic significance of topoisomerase II alpha in patients with glioma;DNA拓扑异构酶Ⅱalpha在脑胶质瘤中的表达及与预后的相关性研究
15.Study of the Relationship between Topoismerase and the Prognostic, MDR of Ovarian Cancer;拓扑异构酶与卵巢癌预后及多药耐药关系的研究
16.Emodin inhibited ATP binding to Topoisomerase II to induce DNA double-strand breaks大黄素通过抑制ATP与拓扑异构酶II的结合导致DNA产生双链断裂
17.Screening of inhibitors of recombinant human DNA topoisomerase Ⅰ from mangrove endophytic fungi从红树林内生真菌筛选重组人DNA拓扑异构酶Ⅰ抑制剂的研究
18.Expression of topoisomerase Ⅰ in human pathological scar tissues拓扑异构酶Ⅰ在人病理性瘢痕组织中的表达分析
相关短句/例句

topoisomeraseⅡα拓扑异构酶Ⅱα
1.Amplification of TopoisomeraseⅡα and c-myc Gene in Breast Cancer and Its Correlation with Neoadjuvant Chemotherapy Response;[背景]新辅助化疗已成为局部晚期乳腺癌的标准初始治疗方案,新辅助化疗的疗效是病人长期生存率的重要预后标志,以往的研究提示拓扑异构酶Ⅱα基因(TOPO Ⅱα)可能与蒽环类为主的新辅助化疗疗效相关,可用作预测化疗敏感性的标志。
3)TopoⅡα拓扑异构酶Ⅱα
1.Methods: The expressions of TopoⅡα,GST-π,P-gp in 80 cases of ovarian carcinoma,20 cases of benign ovarian tumor,and 20 cases of normal control were determined by using SP immunohistochemistry and image analysis system.目的:研究卵巢癌中拓扑异构酶Ⅱα(topoisomeraseα,TopoⅡα)、谷胱甘肽S转移酶π(glutathioneStranserasesπ,GSTπ)、P糖蛋白(Pglycoproein,Pgp)的表达与化疗反应性及预后的关系。
4)Topo Ⅱα拓扑异构酶Ⅱα
1.Expression of Topo Ⅱα and Ki-67 in Human Hepatocellular Carcinoma and Its Significance;拓扑异构酶Ⅱα与Ki-67在肝细胞癌中的表达及意义
5)topoisomerase Ⅱ alphaNA拓扑异构酶Ⅱα
6)topoisomeraseⅡalpha(ToPoⅡα)拓扑异构酶Ⅱα(ToPoⅡα)
延伸阅读

DNA拓扑异构酶抑制剂分子式:CAS号:性质:一类能够抑制DNA拓扑异构酶活性的化合物。DNA拓扑异构酶参与催化各种遗传过程中DNA链的断开和再连接。DNA拓扑异构酶抑制剂有助于研究异构酶的作用方式和功能,已发现许多这种抑制剂可作为抗肿瘤药,如鬼臼素(epipodophyllotoxins)等一些拓扑酶Ⅱ的特异性抑制剂。