1)5-aza-cytidine组蛋白脱乙酰化酶抑制剂
1.DNA methyltransferase (DNMT) inhibitor, 5-aza-cytidine (5-aza-C), was widely studied because DNA hypomethylation induced the re-activation of tumor suppressor genes that were silenced by methylation-mediated mechanisms, could inhibit proliferation and induce differentiation of tumor.组蛋白脱乙酰化酶抑制剂苯丁酸钠(sodium phenylbutyrate,SPB)通过对组蛋白去乙酰化酶(histone seacetylase,HDAC)的抑制而达到对肿瘤细胞的生长抑制、诱导分化及诱导凋亡的作用。
英文短句/例句
1.Antitumor Effect Based on the Interaction of DNA Methyltransferase Inhibitor and Histone DeacetylaseInhibitor;DNA甲基化酶抑制剂与组蛋白脱乙酰化酶抑制剂的抗肿瘤研究
2.Histone deacetylases inhibitors anticancer drug:Vorinostat组蛋白去乙酰化酶抑制剂类抗癌药Vorinostat
3.The Design and Synthesis of Cyclic Tetrapeptide Histone Deacetylase Inhibitors;环肽类组蛋白去乙酰化酶抑制剂的设计与合成
4.Advances in the anticancer effect of histone deacetylase inhibitor组蛋白去乙酰化酶抑制剂抗肿瘤的研究进展
5.Studies on Anti-tumor Activities of MS-275-6 and Its Mechanism of Action;组蛋白脱乙酰基酶抑制剂（MS-275-6）的抗肿瘤作用及其作用机制研究
6.The Effects and Mechanisms of Histone Deacetylase Inhibitor DMA-PB on Traumatic Brain Injury in Rats;组蛋白脱乙酰酶抑制剂DMA-PB对创伤性脑损伤的作用及机制
7.Advances of histone deacetylases inhibitors as novel anti-cancer agents in clinical study新型抗肿瘤药组蛋白脱乙酰基酶抑制剂的临床研究进展
8.Synergistic Effect of Histone Deacetylase Inhibitor SBHA with Proteasome Inhibitors Bortezomib or MG-132 on Breast Cancer Cells;组蛋白去乙酰化酶抑制剂与蛋白酶体抑制剂协同抑制乳腺癌细胞及分子机制研究
9.Inhibition Effect of Histone Deacetylase Inhibitor FK228 on Prostate Cancer Cells;组蛋白去乙酰化酶抑制剂FK228对前列腺癌细胞的抑制作用
10.Experimental Study on the Synergistic Inhibition of Hepatoma Cell Lines with Histone Deacetylase Inhibitor and 5-FU;组蛋白去乙酰化酶抑制剂与5-FU协同抑制肝癌细胞的实验研究
11.Immunosuppressive function of histone deacetylases inhibitors:recent progress组蛋白去乙酰化酶抑制剂的免疫抑制功能研究进展
12.Anticancer Activities of Histone Deacetylase and DNA Methyltransferase Inhibitors on Pancreatic Cancer;DNA甲基化酶和组蛋白去乙酰化酶抑制剂治疗胰腺癌的实验研究
13.The Establishment of Screening Models for Histone Deacetylase Inhibitors and Their Application in Screening of the Chinese Traditional Medicine Effective Components;组蛋白去乙酰化酶抑制剂筛选模型的建立及中药有效组分的筛选
14.Histone Deacetylase Inhibitor and Methylase Inhibitor Repress Synergistically Differentiation of HSC;组蛋白去乙酰化酶抑制剂及甲基转移酶抑制剂协同抑制造血干细胞分化
15.Molecular Mechanisms of Histone Deacetylase Inhibitors Induced Mitotic Catastrophe in Tumor Cells;组蛋白去乙酰化酶抑制剂诱导细胞有丝分裂灾变的分子机制探讨
16.Study on the Inhibitory Action of HDACI on Choriocarcinoma Cell JAR Lines in Vitro组蛋白去乙酰基酶抑制剂对绒癌JAR细胞的影响
17.Histone Deacetylase Inhibitors of Polyoxometalates: Screening and Anti-Tumor Activity;多酸类组蛋白去乙酰化酶抑制剂的筛选及抗肿瘤活性研究
18.The Screening and Primary Functional Study of Histone Deacetylase Inhibitors from Polyoxometallates;多酸类组蛋白去乙酰化酶抑制剂的筛选及初步功能研究
相关短句/例句
Histone Deacetylase Inhibitor组蛋白脱乙酰酶抑制剂
3)histone deacetylase inhibitor组蛋白脱乙酰基酶抑制剂
4)histone deacetylase inhibitors组蛋白去乙酰酶抑制剂
1.Progress in the research of histone deacetylase inhibitors;组蛋白去乙酰酶抑制剂的研究进展
5)histone deacetylase(HDAC) inhibitor组蛋白乙酰酶抑制剂
6)histone deacetylase inhibitors组蛋白去乙酰化酶抑制剂
1.Mechanism of histone deacetylase inhibitors for treatment of hematological cancer and their clinical research;组蛋白去乙酰化酶抑制剂治疗血液系统肿瘤的作用机制及临床应用
2.Molecular mechanism of p21~(WAF1/CIP1) expression induced by histone deacetylase inhibitors in HeLa cell line;组蛋白去乙酰化酶抑制剂诱导H eLa细胞p21~(WAF1/CIP1)表达的分子机制研究
3.Mechanism of regulating multidrug resistances by histone deacetylase inhibitors in tumor cells;组蛋白去乙酰化酶抑制剂调节肿瘤细胞多药耐药性的机制
延伸阅读
多巴脱羧酶抑制剂分子式：CAS号：性质：能够抑制多巴脱羧酶活性的一类化学物质，如在曲霉和链霉菌发酵液中发现的一类异黄酮，能够非特异性地抑制多巴脱羧酶活性，对自发性高血压的大鼠有降压作用，活性大小与α-甲基多巴胺相当。
