1)High Mobility Group Box-1 Protein高迁移率族蛋白B1
1.Effects of NF-κB inhibitor pyrrolidine dithiocarbamate (PDTC) on mRNA expression of high mobility group box-1 protein in organs of rats with endotoxic shock;NF-κB抑制剂对内毒素休克大鼠高迁移率族蛋白B1表达的影响
2.Effect of lipopolysaccharide on stimulating high mobility group box-1 protein expression in peritoneal macrophages in rats and its potential signaling mechanism;大鼠腹腔巨噬细胞高迁移率族蛋白B1诱生机制的初步探讨
3.Study on high mobility group box-1 protein inducing endothelial cell activation in vitro;高迁移率族蛋白B1对血管内皮细胞ECV-304活化作用的研究
英文短句/例句
1.Influence of High Mobility Group Box 1 on Migration of Human Cord Blood CD34~+ Cells高迁移率族蛋白B1对人脐血CD34~+细胞迁移的影响
2.Role of HMGB1 in ischemia/reperfusion injury高迁移率族蛋白B1在缺血再灌注损伤中的作用
3.Investigation Progress of the Correlation between HMGB1 and Sepsis高迁移率族蛋白B1与脓毒症关系的研究进展
4.Change in High Mobility Group Box-1 Protein Expression and Its Role in Mediated Multiple Organs Dysfunction after Severe Injury.;严重损伤后高迁移率族蛋白B1的改变及其与多器官损害的关系
5.The Effect of High Mobility Group Box-1 Protein on Dendritic Cells after Thermal Injury in Rats;烧伤后高迁移率族蛋白B1对树突状细胞免疫功能影响的实验研究
6.High Mobility Group Box-1 Protein Acts as a Co-activator of Nuclear Factor of Activated T Cells -2 in Promoting Interleukin-2 Transcription;高迁移率族蛋白B1通过与NFAT2相互作用增强IL-2的转录表达
7.The Expression and Clinical Significance of High Mobility Group Protein B1 in Acute Obstructive Suppurative Cholangitis;高迁移率族蛋白B1在急性梗阻性化脓性胆管炎中表达及临床意义
8.Preparation of HMGB1 Monoclonal Antibody and Its Application in Competitive ELISA;高迁移率族蛋白B1单克隆抗体的制备及其在竞争ELISA中的应用
9.Study for the Relationship between the Level of High Mobility Group Protein B1 with the Theory of Wei Qi Ying Xue;脓毒症患者高迁移率族蛋白B1水平与卫气营血辨证相关性探讨
10.Preparation and Identification of Human HMGB1 and Anti-human HMGB1 Polyclonal Antibody;人高迁移率族蛋白B1及其多克隆抗体的制备与鉴定
11.High Mobility Group Box 1 Protein as an Immune-modulating Factor for Cytokine Gene Expression and Th1/Th2 Polarization in Human T Lymphocytes;高迁移率族蛋白B1对人T淋巴细胞免疫功能影响的体外研究
12.The Role of HMGB1 in Acute Lung Injury after Hemorrhage;高迁移率族蛋白B1在失血性休克所致急性肺损伤中的作用
13.The Potential Mechanism of High Mobility Group Box 1 Protein on Meningioma Pathogenesis and Invasion;高迁移率族蛋白B1诱导脑膜瘤发生及侵袭生长的机制研究
14.The Role of High Mobility Group Box Protein 1 in the Progress of Hepatic Fibrosis高迁移率族蛋白B1在肝纤维化发生发展中的作用及其机制的研究
15.High Mobility Group Protein Box 1 on the Impact of Periodontal Ligament Fibroblasts高迁移率族蛋白B1对牙周膜成纤维细胞影响的研究
16.Immunohistochemistry study of high mobility group box-1 protein in autoimmune hepatitis自身免疫性肝炎肝穿标本中高迁移率族蛋白B1免疫组织化学研究
17.Expression of HMGB1 and NF-κB in cultured neurons of rat after hypoxia/reoxygenation大鼠缺氧/复氧皮质神经元高迁移率族蛋白B1和核因子κB的表达
18.Effect of berberine on serum HMGB1 level of sepsis mice小檗碱对脓毒症小鼠血清高迁移率族蛋白B1水平的影响
相关短句/例句
high mobility group box 1 protein高迁移率族蛋白B1
1.Effects of Xuebijing injection(血必净注射液) on plasma high mobility group box 1 protein in rats after severe scald injury;血必净注射液对烫伤大鼠高迁移率族蛋白B1的影响
2.Changes in high mobility group box 1 protein levels after scald injury and its effect on splenic lymphocyte immunity in rats;烫伤大鼠高迁移率族蛋白B1的变化及其对脾淋巴细胞免疫反应的影响
3.Objective: High mobility group box 1 protein (HMGB1) as a late-acting cytokine mediates lethality of sepsis and systemic inflammation.目的:高迁移率族蛋白B1(HMGB1)作为一种晚期炎症介质,介导了脓毒症和其他系统性炎症的致死性效应。
3)high mobility group protein B1高迁移率族蛋白B1
1.Relation between level of expression of high mobility group protein B1 in hepatic tissue with the severity and prognosis of sepsis in rat;高迁移率族蛋白B1表达水平与大鼠脓毒症严重程度及预后关系的实验研究
2.Study of localization and translocation of human high mobility group protein B1 in eukaryotic cells;人高迁移率族蛋白B1细胞内定位及移位研究
3.Effects of staphylococcal enterotoxin B on high mobility group protein B1 in a guinea pig asthma model and its significance金葡菌肠毒素B对哮喘豚鼠高迁移率族蛋白B1表达的影响及意义
4)HMGB1高迁移率族蛋白B1
1.Preparation of HMGB1 Monoclonal Antibody and Its Application in Competitive ELISA;高迁移率族蛋白B1单克隆抗体的制备及其在竞争ELISA中的应用
2.Objective:To investigate the effect of shuxuening parenteral solution on the changes of HMGB1 and C response protein and lipid peroxidation in the blood of COPD patients.目的:观察舒血宁注射液对COPD患者血液高迁移率族蛋白B1(high mobility group protein box-1,HMGB1)水平、血清脂质过氧化反应程度及C反应蛋白(Creactive protein,CRP)含量的影响。
3.Objective To prepare monoclonal antibody specific for HMGB1 and establish a direct competitive ELISA for assaying serum HMGB1.目的制备高迁移率族蛋白B1(HMGB1)单克隆抗体和建立HMGB1的直接竞争ELISA测定方法。
5)high mobility group box 1高迁移率族蛋白B1
1.Objective To investigate the influence of Ethyl pyruvate(EP) on the level of high mobility group box 1 (HMGB1) in brain injury of infant rats induced by lipopolysaccharide (LPS) and its significance.目的探讨丙酮酸乙酯(EP)对脂多糖(LPS)致幼年大鼠脑损伤中高迁移率族蛋白B1(HMGB1)表达水平的影响及意义。
2.Objective:To study the effects of Salvia miltiorrhiza on the release of high mobility group box 1(HMGB1) from endotoxin-stimulated macrophages and serum HMGB1 level of endotoxemia mice.目的:研究丹参对内毒素脂多糖(lipopolysaccharide,LPS)激活后巨噬细胞高迁移率族蛋白B1(high mob-ility group box 1,HMGB1)释放和内毒素血症小鼠血清HMGB1水平的影响。
6)human high-mobility group box-1(HMGB1)人高迁移率族蛋白B1(HMGB1)
延伸阅读
高迁移率蛋白质分子式:CAS号:性质:真核生物细胞核内的一组含量丰富的染色质非组蛋白。分子中含有25%碱性氨基酸和30%酸性氨基酸,分子量一般小于30 000。由于其在聚丙烯酰胺凝胶电泳中迁移率高而得名。从不同核酸酶选择性地水解有转录活性的染色质的实验中,发现HMG1和HMG2结合在链节DNA上,而HMG14和HMG17常与核小体核心部分的组蛋白八聚体和DNA结合。认为前者在链节处取代组蛋白亚基H1,后者则作用于核小体的核心颗粒,使之修饰成对DNase I等核酸酶更敏感的转录活性染色质,对基因表达起调控作用。荧光免疫法发现,细胞S期的HMG含量高于丝裂期。HMG14和HMG17还可用作亲和层析配体,分离有转录活性的染色质。
