1)naphthyridine[n?f'θiridin]萘啶
1.7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxyl.本文以氟乙酸甲酯和甲酸乙酯、氰乙酰胺为原料,经缩合、环合反应制得2,6-二羟基-5-氟菸腈,再经氯化、水解反应得到2,6-二氯-5-氟菸酸,该产物经酰化反应得到2,6-二氯-5-氟-吡啶-3-甲酰氯,再经取代、缩合、环合反应得到7-氯-1-环丙基-6-氟-1,4-二氢-4-氧代-1,8-萘啶-3-羧酸乙酯,再经哌嗪缩合、水解、酸化得到目标化合物。
2.Methods Based on several ARIs existed,three naphthyridine derivatives have been designed and synthesized via four steps of reaction,and the ALR2 activity of them three were tested.方法基于几种已存在的醛糖还原酶抑制剂的结构,经过4步反应,合成了三种萘啶衍生物,并对其进行体外ALR2活性测试。
3.A new way for synthesizing bromo-、chloro-naphthyridine was repord in this thsisi.采用新的路线合成溴代、氯代萘啶,以氨基吡啶为原料,利用氨基的强定位效应得到单取代的溴代、氯代氨基吡啶,再通过Skraup关环得到不同位置、单一取代的溴代、氯代萘啶。
英文短句/例句
1.Study on Pharmaconkinetics of Pyronaridine in Mice磷酸咯萘啶在小鼠体内的药动学过程
2.Study on the preparative procedure of inclusion compound of PND-HP-β-CD咯萘啶-羟丙基-β-环糊精包合物的制备
3.The FIC obtained confirmed the synergism between PND and S/P.同时证明 ,咯萘啶与磺胺多辛 /乙胺嘧啶之间有协同效应。
4.CRYSTAL STRCTURE OF BIS(1,8-NAPHTHYRIDINE-N-OXIDE)COPPER(Ⅱ)NITRATE二(1,8-萘啶氮氧化物)合硝酸铜(Ⅱ)的晶体结构
5.Synthesis, Photochemical and Photophysical Properties of 1, 8-Naphthyridine Derivetives;1,8-萘啶衍生物的合成、光化学和光物理性质
6.Gene gyrA Mutation in Nalidixic acid-resistant Salmonella paratyphi A耐萘啶酸甲型副伤寒沙门菌gyrA基因突变研究
7.RP-HPLC determination of malaridine phosphate injection and its related substancesRP-HPLC法测定磷酸咯萘啶注射液含量及有关物质
8.Solvent effect on hydroxyl-1,8 naphthyridine derivatives fluorescence properties溶剂效应对1,8-萘啶衍生物荧光性质的影响
9.OBSERVATION ON EFFICACY OF PYRONARIDINE PHOSPHATE AND IT COMBINED WITH DIHYDROARTEMISININ FOR TREATMENT OF MALARIA IN ERITREA, AFRICA磷酸咯萘啶及其合并双氢青蒿素治疗疟疾效果观察
10.1, 8-Naphthyridine-based d~(10) Complexes: Synthesis, Structures and Photophysical Proprerties;1,8-萘啶衍生物及其d~(10)金属配合物:合成、结构及光物理性质
11.The Study of a New Oral Preparation of Tumorous Multidrug-Resistance Inhibit Agent-Pyronaridine Phosphate;肿瘤多药耐药逆转剂—磷酸咯萘啶口服新剂型的研究
12.Study on Polypyridine Derivatives/complexes, Anthracene Derivatives and 1,8-naphthyridine Complexes as Optical Chemosensors;多联吡啶衍生物/配合物、蒽衍生物和1,8-萘啶配合物作为光化学敏感器的研究
13.Study on the Complex of Bi(Ⅲ) with PAN铋(Ⅲ)与1-(2-吡啶偶氮)-2-萘酚配合物的研究
14.Photochemical properties of naphthalimide derivative grafted in MCM-41 by covalent bond键连在MCM-41哌啶萘酰亚胺的光化学性能
15.Effective Preparation and Fluorescent Properties of Novel Naphthooxepinoquinolinones and Naphthoacridinediones新型萘并氧杂并喹啉酮和萘并吖啶二酮的合成及其荧光性质的研究
16.She received nalidixic acid treatment for two weeks, then the urine was normal. She was advised to keep on nitrofuradantin treatment for three months.使用萘丁酸治疗二周后,尿检正常。建议继续应呋喃旦啶3个月。
17.Spectrophotometric Determination Of Micro 1-(5-Nitro-2-Pyridylazo)-2.7-DihydroxyNaphthalene;1-(5-硝基2-吡啶偶氮)-2.7-萘二酚分光光度法测定微量铜的研究
18.Synthesis of Osmafuran, Osmanaphthalene and Osmapyridine by [4+1], [5+1] and [4+2] Cyclization Methods[4+1]、[5+1]和[4+2]关环法合成锇呋喃、锇萘和锇吡啶
相关短句/例句
naphthyridinone萘啶酮
3)Naphthyridine[n?f'θiridin]1,8-萘啶
1.The research progression of the compounds and coordination compounds of 1,8-Naphthyridine and its derivative;1,8-萘啶类化合物及其配合物的研究进展
4)nalidixic acid萘啶酸
1.A method for the determination of cinoxacin and nalidixic acid in human plasma by reverse-phase high performance liquid chromatography is introduced.提出了同时测定人血浆中的西诺沙星和萘啶酸的高效液相色谱方法。
2.enterocolitica isolates to quinolones and other antibiotics,and to explore the quinolone resistance determining region (QRDR) mutations in nalidixic acid-resistant Y.结果通过对该菌喹诺酮耐药决定区gyrA和parC基因的变异情况检测发现,在22株萘啶酸耐药的菌株中,有20株gyrA基因检出氨基酸变异,其中83位点共检出Ser(AGC)→Arg(AGA或AGG)突变12株,Ile(ATC)突变3株,Cys(TGC)1株,87位点检出Gly(GGC)突变2株,Tyr(TAC)和Asn(AAC)突变各1株;3株萘啶酸敏感O∶3血清型小肠结肠炎耶尔森菌未检出上述氨基酸位点突变,而parC基因无论耐药株或敏感株均未检出突变。
5)Nalidixic acid萘啶酮酸
1.Research on Effect of Nalidixic acid defending Bombys mori against Bombys mori Nucleopolyhedrosis Virus;萘啶酮酸对家蚕血液型脓病防治效果的研究
6)1,6-naphthyridine1,6-萘啶
延伸阅读
萘啶分子式:CAS号:性质:又名吡啶并吡啶(pyridopyridine)或二氮杂萘(diazanaphthalene)。由两个吡啶环稠合而成。有多种异构体,其中:1,5-萘啶,淡黄色针状晶体。有苦味。熔点75℃。沸点112℃(1.99kPa)。1,8-萘啶,针状晶体,有苦味,熔点98~99℃。两者均易溶于水、乙醇、乙醚和苯。具碱性,性质稳定。用作有机合成试剂。