萘啶,naphthyridine
1)naphthyridine[n?f'θiridin]萘啶
1.7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxyl.本文以氟乙酸甲酯和甲酸乙酯、氰乙酰胺为原料,经缩合、环合反应制得2,6-二羟基-5-氟菸腈,再经氯化、水解反应得到2,6-二氯-5-氟菸酸,该产物经酰化反应得到2,6-二氯-5-氟-吡啶-3-甲酰氯,再经取代、缩合、环合反应得到7-氯-1-环丙基-6-氟-1,4-二氢-4-氧代-1,8-萘啶-3-羧酸乙酯,再经哌嗪缩合、水解、酸化得到目标化合物。
2.Methods Based on several ARIs existed,three naphthyridine derivatives have been designed and synthesized via four steps of reaction,and the ALR2 activity of them three were tested.方法基于几种已存在的醛糖还原酶抑制剂的结构,经过4步反应,合成了三种萘啶衍生物,并对其进行体外ALR2活性测试。
3.A new way for synthesizing bromo-、chloro-naphthyridine was repord in this thsisi.采用新的路线合成溴代、氯代萘啶,以氨基吡啶为原料,利用氨基的强定位效应得到单取代的溴代、氯代氨基吡啶,再通过Skraup关环得到不同位置、单一取代的溴代、氯代萘啶
英文短句/例句

1.Study on Pharmaconkinetics of Pyronaridine in Mice磷酸咯萘啶在小鼠体内的药动学过程
2.Study on the preparative procedure of inclusion compound of PND-HP-β-CD咯萘啶-羟丙基-β-环糊精包合物的制备
3.The FIC obtained confirmed the synergism between PND and S/P.同时证明 ,咯萘啶与磺胺多辛 /乙胺嘧啶之间有协同效应。
4.CRYSTAL STRCTURE OF BIS(1,8-NAPHTHYRIDINE-N-OXIDE)COPPER(Ⅱ)NITRATE二(1,8-萘啶氮氧化物)合硝酸铜(Ⅱ)的晶体结构
5.Synthesis, Photochemical and Photophysical Properties of 1, 8-Naphthyridine Derivetives;1,8-萘啶衍生物的合成、光化学和光物理性质
6.Gene gyrA Mutation in Nalidixic acid-resistant Salmonella paratyphi A耐萘啶酸甲型副伤寒沙门菌gyrA基因突变研究
7.RP-HPLC determination of malaridine phosphate injection and its related substancesRP-HPLC法测定磷酸咯萘啶注射液含量及有关物质
8.Solvent effect on hydroxyl-1,8 naphthyridine derivatives fluorescence properties溶剂效应对1,8-萘啶衍生物荧光性质的影响
9.OBSERVATION ON EFFICACY OF PYRONARIDINE PHOSPHATE AND IT COMBINED WITH DIHYDROARTEMISININ FOR TREATMENT OF MALARIA IN ERITREA, AFRICA磷酸咯萘啶及其合并双氢青蒿素治疗疟疾效果观察
10.1, 8-Naphthyridine-based d~(10) Complexes: Synthesis, Structures and Photophysical Proprerties;1,8-萘啶衍生物及其d~(10)金属配合物:合成、结构及光物理性质
11.The Study of a New Oral Preparation of Tumorous Multidrug-Resistance Inhibit Agent-Pyronaridine Phosphate;肿瘤多药耐药逆转剂—磷酸咯萘啶口服新剂型的研究
12.Study on Polypyridine Derivatives/complexes, Anthracene Derivatives and 1,8-naphthyridine Complexes as Optical Chemosensors;多联吡啶衍生物/配合物、蒽衍生物和1,8-萘啶配合物作为光化学敏感器的研究
13.Study on the Complex of Bi(Ⅲ) with PAN铋(Ⅲ)与1-(2-吡啶偶氮)-2-萘酚配合物的研究
14.Photochemical properties of naphthalimide derivative grafted in MCM-41 by covalent bond键连在MCM-41哌啶萘酰亚胺的光化学性能
15.Effective Preparation and Fluorescent Properties of Novel Naphthooxepinoquinolinones and Naphthoacridinediones新型萘并氧杂并喹啉酮和萘并吖啶二酮的合成及其荧光性质的研究
16.She received nalidixic acid treatment for two weeks, then the urine was normal. She was advised to keep on nitrofuradantin treatment for three months.使用萘丁酸治疗二周后,尿检正常。建议继续应呋喃旦啶3个月。
17.Spectrophotometric Determination Of Micro 1-(5-Nitro-2-Pyridylazo)-2.7-DihydroxyNaphthalene;1-(5-硝基2-吡啶偶氮)-2.7-萘二酚分光光度法测定微量铜的研究
18.Synthesis of Osmafuran, Osmanaphthalene and Osmapyridine by [4+1], [5+1] and [4+2] Cyclization Methods[4+1]、[5+1]和[4+2]关环法合成锇呋喃、锇萘和锇吡啶
相关短句/例句

naphthyridinone萘啶酮
3)Naphthyridine[n?f'θiridin]1,8-萘啶
1.The research progression of the compounds and coordination compounds of 1,8-Naphthyridine and its derivative;1,8-萘啶类化合物及其配合物的研究进展
4)nalidixic acid萘啶酸
1.A method for the determination of cinoxacin and nalidixic acid in human plasma by reverse-phase high performance liquid chromatography is introduced.提出了同时测定人血浆中的西诺沙星和萘啶酸的高效液相色谱方法。
2.enterocolitica isolates to quinolones and other antibiotics,and to explore the quinolone resistance determining region (QRDR) mutations in nalidixic acid-resistant Y.结果通过对该菌喹诺酮耐药决定区gyrA和parC基因的变异情况检测发现,在22株萘啶酸耐药的菌株中,有20株gyrA基因检出氨基酸变异,其中83位点共检出Ser(AGC)→Arg(AGA或AGG)突变12株,Ile(ATC)突变3株,Cys(TGC)1株,87位点检出Gly(GGC)突变2株,Tyr(TAC)和Asn(AAC)突变各1株;3株萘啶酸敏感O∶3血清型小肠结肠炎耶尔森菌未检出上述氨基酸位点突变,而parC基因无论耐药株或敏感株均未检出突变。
5)Nalidixic acid萘啶酮酸
1.Research on Effect of Nalidixic acid defending Bombys mori against Bombys mori Nucleopolyhedrosis Virus;萘啶酮酸对家蚕血液型脓病防治效果的研究
6)1,6-naphthyridine1,6-萘啶
延伸阅读

萘啶分子式:CAS号:性质:又名吡啶并吡啶(pyridopyridine)或二氮杂萘(diazanaphthalene)。由两个吡啶环稠合而成。有多种异构体,其中:1,5-萘啶,淡黄色针状晶体。有苦味。熔点75℃。沸点112℃(1.99kPa)。1,8-萘啶,针状晶体,有苦味,熔点98~99℃。两者均易溶于水、乙醇、乙醚和苯。具碱性,性质稳定。用作有机合成试剂。