1)promoter methylation启动子区甲基化
1.Objective to investigate the relationship between the promoter methylation of RASSF1A and expression of RASSF1A proteins and tumorigenesis and development in hepatocellular carcinoma,and The significance and value of the promoter methylation of RASSF1A as a new tumor molecule marker in early diagnosis or no wound diagnosis of HCC.方法应用甲基化特异性PCR(MSP)技术检测35例HCC患者癌和癌旁组织及其相应血清、5例正常肝组织和10例健康对照血清中RASSF1A启动子区甲基化状况,同时应用组织芯片技术检测98例HCC患者癌和癌旁组织中RASSF1A蛋白的表达。
2.【Objective】To research the regulation of ABCG2 expression by promoter methylation.【目的】研究ABCG2在多发性骨髓瘤细胞株中的表达及该基因启动子区甲基化状态对ABCG2表达的影响。
3.METHODS: Promoter methylation of RASSF1A status in the serum of HCC patients (n = 35) and normal controls (n = 10) were detected by methylation-specific PCR (MSP).方法:应用甲基化特异性PCR(MSP)技术检测35例HCC患者血清和10例健康对照血清中RASSF1A启动子区甲基化状况。
英文短句/例句
1.Correlation between Gastric Carcinoma and Methylation on Promoter Region of p15 and p16 Genes;胃癌与p15、p16基因启动子区甲基化的关系
2.Detection Aberrant Promoter Methylation of GSTP1 Gene in Hepatocellular Carcinoma;肝细胞癌GSTP1基因启动子区甲基化的研究
3.RASSF1A Promoter Region CpG Methylation in Nephroblastoma;肾母细胞瘤RASSF1A基因启动子区甲基化研究
4.The Research of Promoter Methylation in Glioma MGMT Gene脑胶质瘤MGMT基因启动子区甲基化作用研究
5.Detection of RASSF1A promoter methylation in gastric cancerRASSF1A基因启动子区甲基化在胃癌组织中的检测
6.Methylation status of pig adiponectin promoter and its expression猪脂联素基因启动子区甲基化与其mRNA表达分析
7.Promoter hypermethylation of ID4 gene in pediatric leukemia and its expression白血病ID4基因核心启动子区甲基化及其表达
8.Promoter Hypermethylation of SOCS-1 in Gastric CancerSOCS-1基因启动子区甲基化与胃癌的关系
9.Research on the Promoter Methylation of Apaf-1 Gene in Gliomas人脑胶质瘤中Apaf-1基因启动子区甲基化的研究
10.Promoter Hypermethylation of the Runx3 Gene in Hepatocellular Carcinoma肝细胞癌中Runx3基因启动子区甲基化研究
11.Methylation and mRNA expression of promoter region of apoptotic protease activating factor-1 gene in pituitary adenomas垂体腺瘤凋亡蛋白酶活化因子-1基因启动子区甲基化与其mRNA表达
12.The Relationship between Atherosclerosis and the Status of 12/15-lipoxygenase Gene Promoter Methylation动脉粥样硬化与12/15-LOX基因启动子区甲基化状态的关系
13.Expression and Promoter Methylation of Apaf-1 Gene and DAPK Gene in Oral Squamous Cell Carcinoma口腔鳞状细胞癌中Apaf-1基因、DAPK基因表达及启动子区甲基化研究
14.The Research on Expression and Promoter Methylation of RASSF1A Gene in Gastric-Carcinoma;RASSF1抑癌基因在胃癌中的表达及其启动子区甲基化的研究
15.Detection of Methylation of the p16 and p15 Gene Promoter in Hepatocellular Carcinoma;原发性肝细胞癌中p16、p15基因启动子区甲基化状态检测
16.Promoter Hypermethylation of DNA Repaired Gene MGMT in Gliomas;DNA修复基因MGMT启动子区过甲基化与脑胶质瘤
17.Study on methylation of CpG island in the promoter region of DAPK gene in gastric cancer胃癌中DAPK基因启动子区CpG岛高甲基化的研究
18.Detection of Promoter Hypermethylation of WIF-1 Gene by Nested Methylation Specific Polymerase Chain Reaction in Lung Cancer Patients巢式甲基化特异性PCR检测肺癌病人WIF-1基因启动子区异常甲基化
相关短句/例句
promoter methylationDNA启动子区甲基化
1.Objective: To study the expression of Cdc42,Survivin,P16 and promoter methylation in Hazak’s esophageal cancer.方法:用RT-PCR方法测定mRNA表达,甲基化特异PCR方法检测DNA启动子区甲基化。
3)Promoter Methylation启动子甲基化
1.Effects of hMLH1 promoter methylation on esophageal carcinoma;错配修复基因启动子甲基化对食管癌发生的作用
2.Promoter methylation and mRNA expression of DKK-3 gene in hepatocellular carcinomaDKK-3和WIF-1基因启动子甲基化状态与肝细胞癌的关系研究
3.The promoter methylation status of the genes was assessed by methylation-specific PCR(MSP).01),且其启动子甲基化程度明显增强。
4)methylation of hMLH1 and hMSH2 promoterhMLH1和hMSH2基因启动子区甲基化
5)gene promoter methylation基因启动子甲基化
6)Hypermethylated GSTP1 promoter高甲基化GSTP1启动子
延伸阅读
启动子分子式：CAS号：性质：(一)在DNA分子上，可被RNA聚合酶识别并与之结合的一段序列，位于结构基因的上游，在那里使转录起动。强的启动子可转录出更多的nRNA。因而在重组工作菌中常使用强制的启动子，以期取得更多的表达量。（二）一种致癌因素，在癌变过程的第二阶段或多阶段机制中造成第二阶段（促进阶段）；一种辅助致癌物。
