纯合性缺失,Homozygous deletion
1)Homozygous deletion纯合性缺失
1.Detection of homozygous deletion and mutation of exon 5 and exon 8 of FHIT gene in differentiated thyroid carcinoma tissue;分化型甲状腺癌组织中脆性组氨酸三联体基因外显子5、8纯合性缺失及突变检测
2.The homozygous deletion was detectyed by multiple PCR analysis and mutation by PCR-SSCP and DNA sequencing followed.方法采用多重PCR、PCR-SSCP和DNA测序对62例胃癌、癌旁组织及10例正常胃黏膜标本中p16INK4a基因纯合性缺失和突变进行检测。
3.Aim: To investigate the frequencies of homozygous deletion of entire coding exons of fragile histidine triad (FHIT) gene in laryngeal squamous cell carcinoma (LSCC) tissue and its clinical significance.目的:探讨喉鳞癌(LSCC)组织中脆性组氨酸三联体(FHIT)基因编码外显子纯合性缺失及其临床意义。
英文短句/例句

1.The Clinical Significance of the Detection of Homozygous Deletion of p16 Gene in Pleural Effusion;胸水p16基因纯合性缺失的检测及其临床意义
2.A Simplified Approach for Detecting Homologous Deletion of SMN1 Genes in Spinal Muacular Atrophy一种简化的检测SMN1基因纯合性缺失的方法
3.Homozygous Deletion, Methylation, Expression and Microsatellite Instability of FHIT Gene in Laryngeal Squamous Cell Carcinoma;喉鳞癌中FHIT基因纯合性缺失、甲基化、表达及其微卫星不稳定性研究
4.Study on the Homozygous Deletion and Point Mutation of P16 Gene Exons of Keratinocytes in Psoriasis;银屑病角质形成细胞p16基因外显子纯合性缺失与点突变的研究
5.Homozygous deletion of FHIT gene exon5,8 and the expression of FHIT protein in gastric carcinoma胃癌中FHIT基因外显子5、8纯合性缺失及其蛋白表达的研究
6.Homozygous Deletions of Exon5, 8 and Protein Expression of the Tumor-suppressor Gene FHIT in Endometrial Carcinomas;子宫内膜癌中抑癌基因FHIT第5和第8外显子纯合性缺失与蛋白表达的研究
7.The Study of Death-Associated Protein Kinase Alterations in Circulating DNA of Transitional Cell Carcinoma of the Bladder: Promoter Methylation and Homozygous Deletion;膀胱移行细胞癌患者外周血循环DNA死亡相关蛋白激酶的甲基化与纯合性缺失的研究
8.Study on the Relationship between 22q11 Microdeletion and Simple Congenital Heart Disease;单纯性先天性心脏病22q11微缺失的研究
9.On Fault after "Straightforwardness" and "Naivety"-More Discussion on Post 80 Writing Trend of Thought;“率性”、“纯真”后的缺失——“80后”写作思潮再论
10.Prokaryotic Expression, Purification and Antibody Production of sp56-lost of Rat Sperm ZP3 Binding Protein sp56;大鼠精子ZP3结合蛋白sp56缺失肽的原核表达、纯化及其抗体的制备
11.Frequency of 22q11 deletions in children with isolated conotruncal defects单纯性圆锥动脉干畸形患者染色体22q11.2微缺失的研究
12.Experimental Study of Loss of Heterozygosity and Imprinting of CDKN1C on Laryngeal Squamous Cell Carcinoma;喉鳞状细胞癌中CDKN1C基因杂合性缺失和印记缺失的实验研究
13.The Relationship between the Loss of Heterozygosity and Loss of Expression of p57~(kip2) mRNA人肝癌p57~(kip2)基因表达缺失与杂合性缺失的关系研究
14.It also expounds Bahkin's discussion about three errors in formalism.巴赫金从三个方面指出了形式方法的“纯技术(言)错误:本体化悖谬、美性缺失、新性丧失。
15.The Legitimacy Defect and Integration of the System of "Deferred Prosecution";“暂缓不起诉”制度的合法性缺失及其整合
16.Study of the Combination of Acupuncture and Chinese Medicine in Treating Acute Ischemic Stroke Patients with Aphasia;针药结合治疗急性缺血性中风失语症研究
17.Loss of Heterozygosity Analysis at 6q16-q23 in Pathogenesis of Non-Hodgkin Lymphomas;6q16-q23杂合性缺失与NHL发病相关性的初步研究
18.Investigation of the Loss of the Heterozygosity to nm23-H_1 Gene and Its Association with the Biocharicteristics of Lung Cancer;nm23-H_1基因杂合性缺失与肺癌生物学特性
相关短句/例句

homozygous deletion纯合缺失
1.RESULTS: No homozygous deletion of p16 gene exon 1, 2 and 3 was observed in any of the 33 cases and no point mutation of p16 gene exon 2 was detected in 10 specimens.结果:所有标本均未检出纯合缺失,10例标本进行了外显子2的序列测定,也未发现点突变。
2.Methods: Polymerase chain reaction (PCR) and sequencing analysis were used to detect the homozygous deletion and point mutation of p16 gene in 84 cases of primary hepatocellular carcinomas and their adjacent liver tissues.方法采用聚合酶链反应(PCR)和全自动序列分析的方法,研究84例肝癌和癌旁肝组织中pl6基因第1、2外显子纯合缺失和点突变的情况。
3.The frequency of homozygous deletion was 8.结果发现2例弥漫型胃癌有 p16基因的纯合缺失,缺失频率为8。
3)homozygous mutant gene基因纯合缺失
4)homozygous deletions纯合性丢失
5)loss of heterozygosity杂合性缺失
1.Identification of some macrosatillite sites of chromosome 19 in primary gastric carcinoma with loss of heterozygosity;19号染色体微卫星杂合性缺失与原发性胃癌的临床关系
2.Analysis of loss of heterozygosity in tk gene of L5178Y mouse lymphoma cells induced by colchicine and vincristine;秋水仙碱和长春新碱诱导L5178Y小鼠淋巴瘤细胞tk基因杂合性缺失分析
3.Study of loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma;胃癌FHIT基因杂合性缺失及微卫星不稳定性的研究
6)LOH杂合性缺失
1.Study on 10q23 LOH and Both Mutation and Expression of PTEN Gene of the Oesophageal Squamous Cell Carcinomas in Chinese Population;中国人食管癌10q23杂合性缺失和PTEN基因突变及表达研究
2.Methods PCR-denaturing polyacrylamide gel electrophoresis-silver staining method was used to detect LOH of three mic- rusatellite locus located in the WWOX gene site of 31 breast cancer tissues.目的检测乳腺癌组织中WWOX基因的杂合性缺失(LOH)状况及WWOX蛋白的表达状况,并探讨其与乳腺癌临床病理参数之间的关系。
3.Objective:To detect the loss of heterozygosity(LOH) of ING1 gene microsatellite and the expression of p33ING1b protein in lung carcinoma and to investigate their association with the carcinogenesis of lung cancer.目的:检测肺癌中抑癌基因ING1微卫星杂合性缺失(LOH)及其主要蛋白产物p33ING1b的表达情况,以探讨ING1基因改变与肺癌发生发展的关系。
延伸阅读

中枢性感觉缺失中枢性感觉缺失central anesthesia  脊髓或脑病变引起的感觉障碍。可分为传导束型(脊髓脑干损伤伤及感觉传导束)、丘脑型(丘脑痛)、内囊型(三偏症)和皮质型(单肢麻木)等不同类型。